Tetracycline HCl solution as a root canal irrigant

The effect of tetracycline hydrochloride as an endodontic irrigant on smear layer removal was examined by scanning electron microscopy and compared with bidistilled water, 2.5% sodium hypochlorite (NaOCl), and 50% citric acid in 20 extracted teeth. Five teeth, as a control, were irrigated with bidistilled water only in group 1. All the other groups were irrigated with NaOCl during instrumentation. The final rinses were NaOCl in group 2, citric acid in group 3, and 1 % tetracycline hydrochloride in group 4. Scanning electron microscopic results and statistical analysis revealed that bidistilled water and NaOCl were ineffective in removing the smear layer, whereas citric acid and tetracycline hydrochloride were significantly more effective (p 0.05). However tetracycline hydrochloride demineralized less peritubular dentin

Comparison of four different suture materials in soft tissues of rats

OBJECTIVES: The purpose of this in vivo study was to histopathologically evaluate the inflammatory reaction incited by Vicryl in rats and compare this material with various suture materials that are widely used in the clinic. SUBJECTS AN

The frequency of lung cancer in patients with pulmonary hamartomas: An evaluation of clinical, radiological, and pathological features and follow-up data of 96 patients with pulmonary hamartomas

Purpose: To investigate the frequency of lung cancer in patients with pulmonary hamartomas and to evaluate clinical, radiological, and pathological characteristics of pulmonary hamartomas. Basic procedures: We reviewed pathology records of pulmonary hamartomas diagnosed between 2003 and 2014. Medical records and the hospital electronic database were also reviewed for each patient to obtain clinical, radiological, and pathological characteristics of pulmonary hamartomas and accompanying malignancies. Main findings: Ninety-six patients with pulmonary hamartomas were identified. There were 26 females (27%) and 70 males (73%), with a mean age of 56.2 years (range 22â87 years). Malignancies were detected in 23 patients (24%), which developed previously in five patients (1 synchronous, 4 metachronous lesions), and concomitantly in 18 patients (with origin from the lung in 17 patients and from the pleura in 1 patient). Principal conclusions: Our results show that patients with pulmonary hamartomas may have coexisting lung malignancies. Keywords: Hamartoma, Lung neoplasms, Diagnosi

Efficacy of hyaluronic acid spray on swelling, pain, and trismus after surgical extraction of impacted mandibular third molars.

The aim of this study was compare the efficacies of two oral sprays in reducing swelling, pain, and trismus after the extraction of impacted mandibular third molars. This prospective double-blind, randomized, crossover clinical trial included 34 patients with bilateral symmetrically impacted mandibular third molars of similar surgical difficulty. Hyaluronic acid or benzydamine hydrochloride spray was applied (two pumps) to the extraction area, three times daily for 7 days. Swelling was evaluated using a tape measure method, pain with a visual analogue scale (VAS), and trismus by measuring the maximum inter-incisal opening. Assessments were made on the day of surgery and on days 2 and 7 after surgery. Statistically significant differences were detected for the swelling and trismus values between the two treatment groups on the second postoperative day (P = 0.002 and P = 0.03, respectively). However, there was no statistically significant difference in VAS scores between the two groups. The administration of hyaluronic acid spray was more effective than benzydamine hydrochloride spray in reducing swelling and trismus. Although no evidence of a reduction in pain levels was detected, hyaluronic acid appears to offer a beneficial effect in the management of swelling and trismus during the immediate postoperative period following impacted third molar surgery