SIRNAK PROVİNCE FİRST TRİMESTER PRENATAL SCREENİNG TEST CURRENT MEDİAN VALUES

Purpose: We aimed to compare the current median values of hormone levels used in screening tests performed during the first trimester in pregnant women in Şırnak with the medians of standard software used in hormone devices and to reveal the differences between them. Materials and Methods: In the study, the data of 301 pregnant women who applied to the hospital in Şırnak province between 01/05/2021 and 01/05/2022 were used by pulling prenatal dual screening test measurements from the hospital database after the hospital permission and ethics committee approval were obtained. The MoM levels found according to the median values calculated by the device software and the multiples of the medians (MoM) calculated according to the weekly median levels entered in the program were compared. Results: Current median levels of free β-HCG were found to be statistically significantly different and lower than those used in screening tests at 11, 12, and 13 weeks of gestation (p<0.01). Current median levels of PAPP-A were statistically significantly different from the software median levels of 11 and 12 weeks of gestation (p<0.01). Free β-HCG and PAPP-A Current MoM averages were statistically significantly different and lower than software MoM levels in both (p<0.01). Conclusion: In this study, it was discussed that comparative data using the current median and local levels of the calculations made to reveal the risk levels of risky pregnancies would also increase the importance and performance of prenatal screening tests

Evaluation of the level of serum Interleukins (IL-2, IL-4, IL-15 andIL-17) and its relationship with disease severity in patients with alopecia areata

Background: Alopecia areata (AA) is a hair disease that causes hair loss without scarring. The etiopathogenesis of AA has not been fully understood yet