Main effect <i>p-values</i> for bladder cancer risk (overall and for each subphenotype) for each tag-SNP under the additive mode of inheritance.

<p>A SNP <i>p-value</i> above the red line is considered as associated with the phenotype after multiple testing correction by Bonferroni (4.2 for main effects and 3.6 for subtypes). All models are adjusted for age, gender, region and cigarette smoking status.</p

Significant SNPs at α = 0.05 in the logistic regression main effect models.

<p><i>MAF(a)</i>, minor allele frequency); <i>pHWE</i>, <i>p-value</i> from the Hardy Weinberg equilibrium test; <i>MOI</i>, Mode of Inheritance.</p><p><i>Repr. (%)</i>, percentage reproducibility assessing the robustness of each SNP by LASSO.</p><p>All models are adjusted for age, gender, region and smoking status.</p><p>Odd ratio and 95%CI under the model of inheritance that provided the lowest <i>p-value</i>, and percentage reproducibility from LASSO under the additive mode of inheritance.</p