Temporal development of plasma levels of MMP-9 (ng/ml) in burn patients.

<p>Blue bars represent TBSA<20% patients and green bars TBSA>20% patients. The gray bar represents values from six healthy controls. Samples are grouped in time intervals, calculated from the time of injury. A Kruskall-Wallis test was performed for each time group, except time group 12 (1 patient). After using the Bonferroni correction for multiple comparisons, significance was set at <i>P</i><0.003. No significant differences were found at any time-point.</p

MMP-9 in plasma and burn blister fluid.

<p>The boxplot demonstrates the relationship between MMP-9 levels (ng/ml) in plasma and burn blister fluid, of patients (N = 14, five TBSA<20%, nine TBSA>20%) on admission. Patients with blister fluid samples were included in the comparison.</p

Baseline and burn characteristics of patients.

<p>Baseline and burn characteristics of patients.</p

Temporal development of plasma levels of MMP-8 (ng/ml) in burn patients.

<p>Blue bars represent TBSA<20% patients and green bars TBSA>20% patients. The gray bar represents the values from six healthy controls. Samples are grouped in time intervals, calculated from the time of injury. A black asterisk indicates a statistically significant difference compared with healthy controls. A Kruskall-Wallis test was performed for each time group, except time group 12 (1 patient). After using the Bonferroni correction for multiple comparisons, significance was set at <i>P</i><0.003. No significant differences were found between the TBSA>20% and TBSA>20% groups at any time-point.</p

Comparison of TIMP-1 in 90-day survivors and 90-day non-survivors.

<p>Plasma levels of TIMP-1 (ng/ml) at a 24- to 48-hour time interval in 90-day survivors and non-survivors.</p

Temporal development of plasma levels of TIMP-1 (ng/ml) in burn patients.

<p>Blue bars represent TBSA<20% patients and green bars TBSA>20% patients. The gray bar represents values from six healthy controls. Samples are grouped in time intervals, calculated from the time of injury. A black asterisk indicates a statistically significant difference compared with healthy controls. A Kruskall-Wallis test was performed for each time group, except time group 12 (1 patient). After using the Bonferroni correction for multiple comparisons, significance was set at <i>P</i><0.003.</p

MMP-8, MMP-9, and TIMP-1 peak and time-adjusted mean concentrations and timing of the peak levels within 72 hours of burn injury.

<p>MMP-8, MMP-9, and TIMP-1 peak and time-adjusted mean concentrations and timing of the peak levels within 72 hours of burn injury.</p

Correlation of TIMP-1 and SOFA score.

<p>Scatter plot represents the correlation between plasma TIMP-1 (ng/ml) and SOFA score in TBSA>20% patients.</p

Temporal development of plasma TIMP-1 (ng/ml) in 90-day survivors and 90-day non-survivors.

<p>TIMP-1 plasma concentrations in 90-day survivors (blue) and non-survivors (red) are shown as a function of time. Samples are grouped in time intervals, calculated from the time of injury. A black asterisk indicates a statistically significant difference between groups. A Kruskall-Wallis test was performed for each time group, except time group 12 (1 patient). After using the Bonferroni correction for multiple comparisons, significance was set at <i>P</i><0.003.</p

Comparison of 90-day survivors and 90-day non-survivors.

<p>Comparison of 90-day survivors and 90-day non-survivors.</p