2 research outputs found
Consumers’ Willingness to Pay for Cassava Flour Inclusion in Bread, a Case Study of Lagos State, Nigeria
The study was conducted to address the issue of consumers’ willingness to pay for inclusion of cassava flour in bread in Lagos State. The data were collected randomly from a sample of 300 respondents in the state through the use of a well structured questionnaire. The contingent valuation method was adopted to estimate both the mean willingness to pay of consumers and the factors that affect their willingness to pay and these were analyzed using the bivariate probit model. The most significant model was the 10percent cassava flour inclusion as it has the highest number of significant variables (eight) followed by 20percent cassava flour inclusion with seven significant variables and 30 and 40percent cassava flour inclusion with six significant variables each. The factors that influenced consumers’ willingness to pay for CCW bread were the respondent’s age, gender, respondents’ awareness, married respondents, respondents with head position,and bread share which is the proportion of respondents income spent on bread to total income. The mean willingness to pay for bread with an inclusion of cassava flour at 10, 20, 30, and 40percent cassava flour inclusion were ?172.70, ?165.00, ?154.07, and ?142.78 respectively for initial bid while the mean willingness-to-pay at 10, 20, 30, and 40percent cassava flour inclusion were ?180.20, ?150.41, ?143.35, and ?127.36 respectively for subsequent bid. Arising from the result of this study, birth control policies were recommended among respondents in the study area
Second asymptomatic carotid surgery trial (ACST-2) : a randomised comparison of carotid artery stenting versus carotid endarterectomy
Background: Among asymptomatic patients with severe carotid artery stenosis but no recent stroke or transient cerebral ischaemia, either carotid artery stenting (CAS) or carotid endarterectomy (CEA) can restore patency and reduce long-term stroke risks. However, from recent national registry data, each option causes about 1% procedural risk of disabling stroke or death. Comparison of their long-term protective effects requires large-scale randomised evidence.
Methods: ACST-2 is an international multicentre randomised trial of CAS versus CEA among asymptomatic patients with severe stenosis thought to require intervention, interpreted with all other relevant trials. Patients were eligible if they had severe unilateral or bilateral carotid artery stenosis and both doctor and patient agreed that a carotid procedure should be undertaken, but they were substantially uncertain which one to choose. Patients were randomly allocated to CAS or CEA and followed up at 1 month and then annually, for a mean 5 years. Procedural events were those within 30 days of the intervention. Intention-to-treat analyses are provided. Analyses including procedural hazards use tabular methods. Analyses and meta-analyses of non-procedural strokes use Kaplan-Meier and log-rank methods. The trial is registered with the ISRCTN registry, ISRCTN21144362.
Findings: Between Jan 15, 2008, and Dec 31, 2020, 3625 patients in 130 centres were randomly allocated, 1811 to CAS and 1814 to CEA, with good compliance, good medical therapy and a mean 5 years of follow-up. Overall, 1% had disabling stroke or death procedurally (15 allocated to CAS and 18 to CEA) and 2% had non-disabling procedural stroke (48 allocated to CAS and 29 to CEA). Kaplan-Meier estimates of 5-year non-procedural stroke were 2·5% in each group for fatal or disabling stroke, and 5·3% with CAS versus 4·5% with CEA for any stroke (rate ratio [RR] 1·16, 95% CI 0·86-1·57; p=0·33). Combining RRs for any non-procedural stroke in all CAS versus CEA trials, the RR was similar in symptomatic and asymptomatic patients (overall RR 1·11, 95% CI 0·91-1·32; p=0·21).
Interpretation: Serious complications are similarly uncommon after competent CAS and CEA, and the long-term effects of these two carotid artery procedures on fatal or disabling stroke are comparable