Multivariate analysis of factors associated with the occurrence of Q151M and K65R mutations.

†<p>Odd ratio estimated using logistic analysis.</p>‡<p>95% Confident interval.</p

Substitutions and their positions in <i>ldh</i> nucleotide sequences (numbers correspond to base pair positions and were defined according to the complete sequence of the <i>P. falciparum ldh</i> gene PF13_0141).

<p>Non synonymous mutations are shown in brackets.</p

Parasite taxa, with host name, geographical location and GenBank accession number of the <i>cyt b</i> and <i>cox1</i> sequences used for the phylogenetic analysis

<p>Parasite taxa, with host name, geographical location and GenBank accession number of the <i>cyt b</i> and <i>cox1</i> sequences used for the phylogenetic analysis</p

Substitutions and their positions in <i>cox1</i> nucleotide sequences (numbers correspond to base pair positions and were defined according to the complete sequence of the <i>P. falciparum cox1</i> gene M76611).

<p>Non synonymous mutations are shown in brackets.</p

Substitutions and their positions in <i>cyt b</i> nucleotide sequences (numbers correspond to base pair positions and were defined according to the complete <i>P. falciparum cyt b</i> gene sequence M76611).

<p>Non synonymous mutation is shown in brackets.</p

Estimates of the proportion of the sampled genomic regions for which the most closely related haplotype comes from each study population, for chimpanzees and humans.

<p>Parentheses show the empirical central 95% region of the distribution of values for the 100 re-samples of the human data.</p

Human <i>P. ovale</i> strains, strain code, geographical location of origin, nucleotide sequence, type and GenBank accession number.

<p>Human <i>P. ovale</i> strains, strain code, geographical location of origin, nucleotide sequence, type and GenBank accession number.</p

Phylogeny of Haemosporidia inferred from <i>cyt b</i> and <i>cox1</i> nucleotide sequences.

<p>Values are bootstrap percentages obtained by maximum likelihood analysis (left of the slash, values under 70% not shown) and Bayesian posterior probabilities (right of the slash, values less then 0.7 not shown), <i>P</i>. = <i>Plasmodium</i>. In red: Human malaria parasite species. Usual hosts are presented on the right side.</p

Map of the geographic distribution of four populations of common chimpanzee.

<p><i>After </i><a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1002504#pgen.1002504-Gonder2" target="_blank">[<i>3</i>]</a><i>, Figure 6b</i>. Colours show the ranges of each population (yellow - <i>P. t. troglodytes</i>, red - <i>P. t. ellioti</i>, blue - <i>P. t. verus</i>, green - <i>P. t. schweinfurthii</i>) with major rivers indicated. The Sanaga River in Cameroon has been proposed to form the boundary between the ranges of <i>P. t. ellioti</i> and <i>P. t. troglodytes</i>.</p

Pairwise F_ST values for human samples.

<p>Parentheses show the empirical central 95% region of the distribution of values for the 100 re-samples of the human data.</p