Principales características de las biopelículas relacionadas con procesos patológicos descritos en humanos en los últimos 10 años, revisión sistemática

Introduction: One of the greatest advances in microbiology has been the knowledge of growth and development of microorganisms on surfaces forming biofilms, and its behavior and physiology are significantly different from those microorganisms that have an individual or planktonic growth. In this study, we describe the main characteristics of biofilms related to pathological processes in humans.Methods: A systematic literature review was conducted in the databases ScienceDirect, PubMed and the generic search engine Google Scholar. In the study were included 35 articles, which met the specific inclusion and exclusion criteria.Results: We describe the etiologic agents involved in the formation of biofilms, the characterization of these organic sites where these can be formed and the pathogenic factors related to the formation of biofilms.Conclusion: Biofilm formation is influenced by animate and inanimate factors involved in the host.Introducción. Uno de los mayores avances en microbiología ha sido el conocimiento del crecimiento de microorganismos sobre diferentes superficies, formando biopelículas, en donde su comportamiento y fisiología es significativamente diferente de aquellos microorganismos que crecen de forma individual o planctónica. En este estudio se describen las principales características de las biopelículas relacionadas con procesos patológicos en humanos.Métodos. Se realizó una revisión sistemática de la literatura relacionada en las bases de datos ScienceDirect, PubMed y el buscador genérico Google Scholar. Se incluyeron en el estudio 35 artículos, los cuales cumplieron con los criterios de inclusión y de exclusión determinados.Resultados. Se describieron los agentes etiológicos involucrados en la formación de biopelículas, así como la caracterización acorde con los sitos orgánicos donde se pueden establecer, y los factores patogénicos relacionados con la formación.Conclusión. En la formación de biopelículas influyen factores animados e inanimados relacionados con características específicas del hospedero

Serological evidence of exposure to some zoonotic microorganisms in cattle and humans with occupational exposure to livestock in Antioquia, Colombia

Bacteria belonging to Anaplasma, Ehrlichia, Rickettsia and Coxiella genera are considered emerging pathogens and livestock is one of the contexts where the transmission of these microorganisms can occur. The goal of this study was to determine serological evidence for the exposure to these bacteria in cattle and humans with occupational exposure to livestock in the subregions North and Magdalena Medio, Antioquia, Colombia, and to explore related factors. A cross-sectional study was conducted in 48 livestock farms distributed in six municipalities from both subregions: Belmira, Entrerríos and San Pedro de los Milagros (North), and Puerto Berrío, Puerto Nare and Puerto Triunfo (Magdalena Medio). Blood samples from 332 people and 384 bovines were evaluated by serology (IgM and IgG) screening for bacteria from the Anaplasma, Ehrlichia, Rickettsia, and Coxiella genera. Seropositivity in humans from both regions was 42.4% (95%CI: 31.2-55.1) for Anaplasma, 74.2% (95%CI: 66.0-84.4) for Ehrlichia, 72.5% (95%CI: 62.1-82.0) for Rickettsia, and 60.7% (95%CI: 59.7-69.1) for Coxiella burnetii. In cattle, seropositivity was 31.6% (95%CI: 19.9-44.2), 66.8% (95%CI: 55.2-78.1), 64.6% (95%CI: 53.8-74.5), and 61.6% (95%CI: 51.9-69.2), respectively. History of biting by ticks, milking, vaccination, having dogs and hens in the residence, as well as the consumption of raw milk derivatives were some factors associated with the infection by the bacteria studied. The results suggest a previous and recent exposure to these zoonotic bacteria genera in people with occupational exposure to livestock, as well as in cattle in the two studied subregions