19,347 research outputs found

    Oesophageal ulceration in HIV-infected patients

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    Objective. To determine the aetiology of oesophageal ulceration in HIV-infected patients. Design. A retrospective clinical, endoscopic and histopathological analysis of patients with confirmed HIV infection and an oesophageal ulcer diagnosed on endoscopy. Setting. A tertiary referral, gastrointestinal clinic in Cape Town. Results. Fifty-one patients with HIV infection and oesophageal ulceration were seen from January 2001 to December 2007. Median CD4 count was 26 cells/µl. Mean age was 35.5 years. Sixty per cent of patients were female. Forty-nine per cent of oesophageal ulcers were idiopathic while 23% were caused by cytomegalovirus infection. The remainder were due to miscellaneous causes. Conclusion. A surprisingly small number of patients with HIV associated oesophageal ulceration were seen during the study period. This may reflect local referral practices or the fact that patients with severe immunosuppression succumb before developing oesophageal ulcers. As in other series, idiopathic oesophageal ulcers and cytomegalovirus ulcers made up the majority of cases. Correct biopsy technique and appropriate histological and microbiological investigations are associated with improved diagnostic yield in these patients

    A Robust AFPTAS for Online Bin Packing with Polynomial Migration

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    In this paper we develop general LP and ILP techniques to find an approximate solution with improved objective value close to an existing solution. The task of improving an approximate solution is closely related to a classical theorem of Cook et al. in the sensitivity analysis for LPs and ILPs. This result is often applied in designing robust algorithms for online problems. We apply our new techniques to the online bin packing problem, where it is allowed to reassign a certain number of items, measured by the migration factor. The migration factor is defined by the total size of reassigned items divided by the size of the arriving item. We obtain a robust asymptotic fully polynomial time approximation scheme (AFPTAS) for the online bin packing problem with migration factor bounded by a polynomial in 1ϵ\frac{1}{\epsilon}. This answers an open question stated by Epstein and Levin in the affirmative. As a byproduct we prove an approximate variant of the sensitivity theorem by Cook at el. for linear programs

    Investment under ambiguity with the best and worst in mind

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    Recent literature on optimal investment has stressed the difference between the impact of risk and the impact of ambiguity - also called Knightian uncertainty - on investors' decisions. In this paper, we show that a decision maker's attitude towards ambiguity is similarly crucial for investment decisions. We capture the investor's individual ambiguity attitude by applying alpha-MEU preferences to a standard investment problem. We show that the presence of ambiguity often leads to an increase in the subjective project value, and entrepreneurs are more eager to invest. Thereby, our investment model helps to explain differences in investment behavior in situations which are objectively identical

    Instability and spatiotemporal rheochaos in a shear-thickening fluid model

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    We model a shear-thickening fluid that combines a tendency to form inhomogeneous, shear-banded flows with a slow relaxational dynamics for fluid microstructure. The interplay between these factors gives rich dynamics, with periodic regimes (oscillating bands, travelling bands, and more complex oscillations) and spatiotemporal rheochaos. These phenomena, arising from constitutive nonlinearity not inertia, can occur even when the steady-state flow curve is monotonic. Our model also shows rheochaos in a low-dimensional truncation where sharply defined shear bands cannot form

    COVID-19 Presenting as Acute Hepatitis

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    Polarization and readout of coupled single spins in diamond

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    We study the coupling of a single nitrogen-vacancy center in diamond to a nearby single nitrogen defect at room temperature. The magnetic dipolar coupling leads to a splitting in the electron spin resonance frequency of the nitrogen-vacancy center, allowing readout of the state of a single nitrogen electron spin. At magnetic fields where the spin splitting of the two centers is the same we observe a strong polarization of the nitrogen electron spin. The amount of polarization can be controlled by the optical excitation power. We combine the polarization and the readout in time-resolved pump-probe measurements to determine the spin relaxation time of a single nitrogen electron spin. Finally, we discuss indications for hyperfine-induced polarization of the nitrogen nuclear spin

    On the Stability of Gas Bubbles in Liquid-Gas Solutions

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    With the neglect of the translational motion of the bubble, approximate solutions may be found for the rate of solution by diffusion of a gas bubble in an undersaturated liquid-gas solution; approximate solutions are also presented for the rate of growth of a bubble in an oversaturated liquid-gas solution. The effect of surface tension on the diffusion process is also considered

    Expanding direction of the period doubling operator

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    We prove that the period doubling operator has an expanding direction at the fixed point. We use the induced operator, a ``Perron-Frobenius type operator'', to study the linearization of the period doubling operator at its fixed point. We then use a sequence of linear operators with finite ranks to study this induced operator. The proof is constructive. One can calculate the expanding direction and the rate of expansion of the period doubling operator at the fixed point

    Causal perturbation theory in terms of retarded products, and a proof of the Action Ward Identity

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    In the framework of perturbative algebraic quantum field theory a local construction of interacting fields in terms of retarded products is performed, based on earlier work of Steinmann. In our formalism the entries of the retarded products are local functionals of the off shell classical fields, and we prove that the interacting fields depend only on the action and not on terms in the Lagrangian which are total derivatives, thus providing a proof of Stora's 'Action Ward Identity'. The theory depends on free parameters which flow under the renormalization group. This flow can be derived in our local framework independently of the infrared behavior, as was first established by Hollands and Wald. We explicitly compute non-trivial examples for the renormalization of the interaction and the field.Comment: 76 pages, to appear in Rev. Math. Phy
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