Research Report 2008–2009

The NHMRC Clinical Trials Centre at the University of Sydney runs large multicentre investigator-initiated clinical trials, takes part in trials of national and international collaborative trial groups and contributes expertise to trials run by others. It also: • undertakes research into trial methods and is recognised through publications as a leader in trial methodology • reviews and synthesises evidence from completed trials, and is at the forefront of developments in methods, such as prospective meta-analysis • advises on trial design and operation, and randomises patients and analyses data for other groups conducting trials, particularly through its Outreach program • takes a lead in proposing new directions for trial research in Australia, particularly with regard to integrating clinical trials with national policy and clinical practice • offers placements for postgraduate students in all of these areas • runs short courses in the design and conduct of clinical trials as part of its undertaking to train people for Australian medical research. Core funding is provided by the NHMRC, and specific projects are funded by government, public and private institutions and the pharmaceutical industry. The CTC is at two sites in Camperdown in inner Sydney — the Medical Foundation Building on Parramatta Road and on Mallett Street. This report covers the CTC’s achievements for the biennium 2008–200

A new type of maxillofacial dysostosis, inherited as an X-linked or autosomal recessive trait

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Congenital conductive hearing loss in the lacrimoauriculodentodigital syndrome

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The chondrosarcoom van de Larynx

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Hearing loss in the Saethre-Chotzen syndrome

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Het alveolaire rabdomyosarcoom met leukemische presentatie

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Notes on Hobson-Jobson

Reprinted from the Indian Antiquary