1,297 research outputs found
High-dimensional unitary transformations and boson sampling on temporal modes using dispersive optics
A major challenge for postclassical boson sampling experiments is the need for a large number of coupled optical modes, detectors, and single-photon sources. Here we show that these requirements can be greatly eased by time-bin encoding and dispersive optics-based unitary transformations. Detecting consecutively heralded photons after time-independent dispersion performs boson sampling from unitaries for which an efficient classical algorithm is lacking. We also show that time-dependent dispersion can implement general single-particle unitary operations. More generally, this scheme promises an efficient architecture for a range of other linear optics experiments.United States. Air Force Office of Scientific Research. Multidisciplinary University Research Initiative (Grant FA9550-14-1-0052
Characterising seizures in anti-NMDA-receptor encephalitis with dynamic causal modelling
We characterised the pathophysiology of seizure onset in terms of slow fluctuations in synaptic efficacy using EEG in patients with anti-N-methyl-d-aspartate receptor (NMDA-R) encephalitis. EEG recordings were obtained from two female patients with anti-NMDA-R encephalitis with recurrent partial seizures (ages 19 and 31). Focal electrographic seizure activity was localised using an empirical Bayes beamformer. The spectral density of reconstructed source activity was then characterised with dynamic causal modelling (DCM). Eight models were compared for each patient, to evaluate the relative contribution of changes in intrinsic (excitatory and inhibitory) connectivity and endogenous afferent input. Bayesian model comparison established a role for changes in both excitatory and inhibitory connectivity during seizure activity (in addition to changes in the exogenous input). Seizures in both patients were associated with a sequence of changes in inhibitory and excitatory connectivity; a transient increase in inhibitory connectivity followed by a transient increase in excitatory connectivity and a final peak of excitatory-inhibitory balance at seizure offset. These systematic fluctuations in excitatory and inhibitory gain may be characteristic of (anti NMDA-R encephalitis) seizures. We present these results as a case study and replication to motivate analyses of larger patient cohorts, to see whether our findings generalise and further characterise the mechanisms of seizure activity in anti-NMDA-R encephalitis
Theory of Pump Depletion and Spike Formation in Stimulated Raman Scattering
By using the inverse spectral transform, the SRS equations are solved and the
explicit output data is given for arbitrary laser pump and Stokes seed profiles
injected on a vacuum of optical phonons. For long duration laser pulses, this
solution is modified such as to take into account the damping rate of the
optical phonon wave. This model is used to interprete the experiments of Druhl,
Wenzel and Carlsten (Phys. Rev. Lett., (1983) vol. 51, p. 1171), in particular
the creation of a spike of (anomalous) pump radiation. The related nonlinear
Fourier spectrum does not contain discrete eigenvalue, hence this Raman spike
is not a soliton.Comment: LaTex file, includes two figures in LaTex format, 9 page
A bright nanowire single photon source based on SiV centers in diamond
The practical implementation of many quantum technologies relies on the
development of robust and bright single photon sources that operate at room
temperature. The negatively charged silicon-vacancy (SiV-) color center in
diamond is a possible candidate for such a single photon source. However, due
to the high refraction index mismatch to air, color centers in diamond
typically exhibit low photon out-coupling. An additional shortcoming is due to
the random localization of native defects in the diamond sample. Here we
demonstrate deterministic implantation of Si ions with high conversion
efficiency to single SiV- centers, targeted to fabricated nanowires. The
co-localization of single SiV- centers with the nanostructures yields a ten
times higher light coupling efficiency than for single SiV- centers in bulk
diamond. This enhanced photon out-coupling, together with the intrinsic
scalability of the SiV- creation method, enables a new class of devices for
integrated photonics and quantum science.Comment: 15 pages, 5 figure
INVERSE SCATTERING TRANSFORM ANALYSIS OF STOKES-ANTI-STOKES STIMULATED RAMAN SCATTERING
Zakharov-Shabat--Ablowitz-Kaup-Newel-Segur representation for
Stokes-anti-Stokes stimulated Raman scattering is proposed. Periodical waves,
solitons and self-similarity solutions are derived. Transient and bright
threshold solitons are discussed.Comment: 16 pages, LaTeX, no figure
Fast thermal relaxation in cavity-coupled graphene bolometers with a Johnson noise read-out
Since the invention of the bolometer, its main design principles relied on
efficient light absorption into a low-heat-capacity material and its
exceptional thermal isolation from the environment. While the reduced thermal
coupling to its surroundings allows for an enhanced thermal response, it in
turn strongly reduces the thermal time constant and dramatically lowers the
detector's bandwidth. With its unique combination of a record small electronic
heat capacity and a weak electron-phonon coupling, graphene has emerged as an
extreme bolometric medium that allows for both, high sensitivity and high
bandwidths. Here, we introduce a hot-electron bolometer based on a novel
Johnson noise readout of the electron gas in graphene, which is critically
coupled to incident radiation through a photonic nanocavity. This
proof-of-concept operates in the telecom spectrum, achieves an enhanced
bolometric response at charge neutrality with a noise equivalent power NEP <
5pW/ Sqrt(Hz), a thermal relaxation time of {\tau} < 34ps, an improved light
absorption by a factor ~3, and an operation temperature up to T=300K
The risk of knee osteoarthritis after different types of knee injuries in young adults: a population-based cohort study
Objectives
To estimate the risk of clinically-diagnosed knee osteoarthritis (OA) after different types of knee injuries in young adults.
Methods
In a longitudinal cohort study based on population-based healthcare data from Skåne, Sweden, we included all persons aged 25-34 years in 1998-2007 (n=149,288) with and without diagnoses of knee injuries according to ICD-10. We estimated the hazard ratio of
future diagnosed knee OA in injured and uninjured persons using Cox regression, adjusted for potential confounders. We also explored the impact of type of injury (contusion, fracture, dislocation, meniscal tear, cartilage tear/other injury, collateral ligament tear, cruciate ligament tear, and injury to multiple structures) on diagnosed knee OA risk.
Results
We identified 5,247 persons (mean [SD] age 29.4 [2.9] years, 67% men) with a knee injury, and 142,825 persons (mean [SD] age 30.2 [3.0] years, 45% men) without. We found an adjusted hazard ratio of 5.7 (95%CI 5.0-6.6) for diagnosed knee OA in injured compared to uninjured persons during the first 11 years of follow-up and 2.7 (95%CI 2.3 – 3.1) during the following 8 years. The corresponding risk difference (RD) after 19 years of follow-up was 8.1% (95%CI 6.7%-9.4%). Cruciate ligament injury, meniscal tear, and fracture of the tibia plateau/patella were associated with greatest increase in risk (RD of 19.6% (95% CI 13.2%-25.9%), 10.5% (95%CI 6.4%-14.7%), and 6.6% (95%CI 1.1%-12.2%), respectively).
Conclusion
In young adults, knee injury increases the risk of future diagnosed knee OA about 6-fold with highest risks found after cruciate ligament injury, meniscal tear, and intraarticular fracture
Climbing the Jaynes-Cummings Ladder and Observing its Sqrt(n) Nonlinearity in a Cavity QED System
The already very active field of cavity quantum electrodynamics (QED),
traditionally studied in atomic systems, has recently gained additional
momentum by the advent of experiments with semiconducting and superconducting
systems. In these solid state implementations, novel quantum optics experiments
are enabled by the possibility to engineer many of the characteristic
parameters at will. In cavity QED, the observation of the vacuum Rabi mode
splitting is a hallmark experiment aimed at probing the nature of matter-light
interaction on the level of a single quantum. However, this effect can, at
least in principle, be explained classically as the normal mode splitting of
two coupled linear oscillators. It has been suggested that an observation of
the scaling of the resonant atom-photon coupling strength in the
Jaynes-Cummings energy ladder with the square root of photon number n is
sufficient to prove that the system is quantum mechanical in nature. Here we
report a direct spectroscopic observation of this characteristic quantum
nonlinearity. Measuring the photonic degree of freedom of the coupled system,
our measurements provide unambiguous, long sought for spectroscopic evidence
for the quantum nature of the resonant atom-field interaction in cavity QED. We
explore atom-photon superposition states involving up to two photons, using a
spectroscopic pump and probe technique. The experiments have been performed in
a circuit QED setup, in which ultra strong coupling is realized by the large
dipole coupling strength and the long coherence time of a superconducting qubit
embedded in a high quality on-chip microwave cavity.Comment: ArXiv version of manuscript published in Nature in July 2008, 5
pages, 5 figures, hi-res version at
http://www.finkjohannes.com/SqrtNArxivPreprint.pd
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