Helicobacter pylori infection is associated with decreased serum levels of high density lipoprotein, but not with the severity of coronary atherosclerosis

<p>Abstract</p> <p>Objective</p> <p>The objective of this survey was to study the association between <it>Helicobacter pylori </it>infection and the severity of coronary atherosclerosis.</p> <p>Methods</p> <p>The study population consisted of 961 consecutive patients (711 males and 250 females) who underwent coronary angiography for suspected or known coronary atherosclerosis. The patients' body mass index, blood pressure, the blood lipid, blood glucose, leukocyte count (10⁹/L), neutrophil count (10⁹/L), and Helicobacter <it>pylori</it>-specific IgG antibodies were performed. Coronary angiograms were scored according to vessel score and Gensini's score.</p> <p>Results</p> <p>A significant association between <it>H. pylori </it>infection and coronary atherosclerosis as well as its severity was not find in this cross section study (<it>p </it>= 0.858). And, the level distribution of vessel score (<it>p </it>= 0.906) and Gensini's score (<it>p </it>= 0.905) were similar in the seropositivity group and seronegativity group of Helicobacter <it>pylori </it>infection. However, the level of fasting high-density lipoprotein cholesterol (mmol/L) (<it>p </it>= 0.013) was significantly lower in the seropositivity group than that in the seronegativity group of Helicobacter <it>pylori </it>infection.</p> <p>Conclusions</p> <p>In conclusion, in the present study, a significantly correlation between Helicobacter <it>pylori </it>seropositivity and angiographically evaluated severity of atherosclerosis was not find. And, the present study showed a good correlation between Helicobacter <it>pylori </it>infection and decreased HDL cholesterol. However, the exact mechanisms need further study.</p

An innovative approach to multi-method integrated assessment modelling of global climate change

© 2020, University of Surrey. All rights reserved. Modelling and simulation play an increasingly significant role in exploratory studies for informing policy makers on climate change mitigation strategies. There is considerable research being done in creating Integrated Assessment Models (IAMs), which focus on examining the human impacts on climate change. Many popular IAMs are created as steady state optimisation models. They typically employ a nested structure of neoclassical production functions to represent the energy-economy system, holding aggregate views on variables, and hence are unable to capture a finer level of details of the underlying system components. An alternative approach that allows modelling populations as a collection of individual and unevenly distributed entities is Agent-Based Modelling, often used in the field of Social Simulation. But simulating huge numbers of individual entities can quickly become an issue, as it requires large amounts of computational resources. The goal of this paper is to introduce a conceptual framework for developing hybrid IAMs. This novel modelling approach allows us to reuse existing rigid, but well-established IAMs, and adds more flexibility by replacing aggregate stocks with a community of vibrant interacting entities. We provide a proof-of-concept of the application of this conceptual framework in form of an illustrative example. Our test case takes the settings of the US. It is solely created for the purpose of demonstrating our hybrid modelling approach; we do not claim that it has predictive powers

Worming the Circular Economy for Biowaste and Plastics: Hermetia illucens, Tenebrio molitor, and Zophobas morio

The negative impact of the modern-day lifestyle on the environment was aggravated during the COVID-19 pandemic through the increased use of single-use plastics from food take-aways to medical supplies. Similarly, the closure of food outlets and disrupted supply chains have also resulted in significant food wastage. As the pandemic rages on, the aggravation of increased waste becomes an increasingly urgent problem that threatens the biodiversity, ecosystems, and human health worldwide through pollution. While there are existing methods to deal with organic and plastic waste, many of the solutions cause additional problems. Increasingly proposed as a natural solution to man-made problems, there are insect solutions for dealing with the artificial and organic waste products and moving towards a circular economy, making the use of natural insect solutions commercially sustainable. This review discusses the findings on how some of these insects, particularly Hermetia illucens, Tenebrio molitor, and Zophobas morio, can play an increasingly important role in food and plastics, with a focus on the latter

INVESTIGATING THE INFLUENCE OF AUTHORITARIAN LEADERSHIP AND SUPERVISOR SATISFACTION ON TURNOVER INTENTION: THE MODERATING ROLE OF EMPLOYEE UPBRINGING

Authoritarian leadership is prevalent in the Asian region, and previous research has found a positive correlation between authoritarian leadership and employees' intention to leave their jobs. However, there are employees in the workplace who can adapt to such supervisors. Therefore, we approach this study from the perspective of "fit theory" to explore whether employees with authoritarian family upbringing can match with authoritarian leadership. This study aims to investigate the impact of authoritarian leadership on employees' intention to leave, with supervisor satisfaction as the mediator and employees' authoritarian family upbringing as the moderator. A total of 232 valid questionnaires were collected in this study. The results revealed that the level of authoritarian family upbringing among employees has a moderating effect on the relationship between authoritarian leadership and supervisor satisfaction

Event Rate of Fast Radio Burst from Binary Neutron-star Mergers

It is proposed that one-off fast radio burst (FRB) with periodic structures may be produced during the inspiral phase of a binary neutron-star (BNS) merger. In this paper, we study the event rate of such kind of FRB. We first investigate the properties of two one-off FRBs with periodic structures (i.e., FRB~20191221A and FRB~20210213A) in this scenario, by assuming the fast magnetosonic wave is responsible for their radio emission. For the luminosities and periods of these bursts, it is found that the pre-merger BNS with magnetic field strength $B\gtrsim 10^{12}\,{\rm Gs}$ is required. This is relatively high compared with that of the most of the BNSs observed in our Galaxy, of which the magnetic field is around $10^{9}\,{\rm Gs}$. Since the observed BNSs in our Galaxy are the binaries without suffering merger, a credited event rate of BNS-merger originated FRBs should be estimated by considering the evolution of both the BNS systems and their magnetic fields. Based on the population synthesis and adopting a decaying magnetic field of NSs, we estimate the event rate of BNS-mergers relative to their final magnetic fields. We find that the rapid merged BNSs tend to merge with high magnetization, and the event rate of BNS-merger originated FRBs, i.e., the BNS-mergers with both NSs' magnetic field being higher than $10^{12}\,{\rm Gs}$ is $\sim8\times10^{4}\,\rm{yr}^{-1}$ ($19 \%$ of the total BNS-mergers) in redshift $z<1$.Comment: 11 pages, 2 figures, accepted for publication in Astrophysical Journa