1,102 research outputs found
Effects of Ox-LDL on Macrophages NAD(P)H Autofluorescence Changes by Two-photon Microscopy
Ox-LDL uptakes by macrophage play a critical role in the happening of
atherosclerosis. Because of its low damage on observed cells and better
signal-to- background ratio, two-photon excitation fluorescence microscopy is
used to observe NAD(P)H autofluorescence of macrophage under difference
cultured conditions- bare cover glass, coated with fibronectin or
poly-D-lysine. The results show that the optimal condition is fibronectin
coated surface, on which, macrophages profile can be clearly identified on
NAD(P)H autofluorescence images collected by two-photon microscopy. Moreover,
different morphology and intensities of autofluorescence under different
conditions were observed as well. In the future, effects of ox-LDL on
macrophages will be investigated by purposed system to research etiology of
atherosclerosis.Comment: Submitted on behalf of TIMA Editions
(http://irevues.inist.fr/tima-editions
Photocatalytic Transfer Hydrogenation Reactions Using Water as the Proton Source
Transfer hydrogenation using liquid hydrogen carriers as
the direct proton sources under mild conditions has received extensive
attention in the research area of organic synthesis. The emerging
photocatalytic water-donating transfer hydrogenation (PWDTH) is a
promising alternative over the conventional hydrogenation technology
due to the advantages of being eco-friendly. This paper focuses on the
recent advances in the rising and rapidly developing field of PWDTH
reactions, devoted to elucidating the mechanism of the hydrogen transfer
process and rationalizing the design principles of efficient photocatalysts.
Finally, the current challenges and future opportunities are described.Web of Science13117567755
Measuring the Hubble Constant Using Strongly Lensed Gravitational Wave Signals
The measurement of the Hubble constant plays an important role in the
study of cosmology. In this letter, we propose a new method to constrain the
Hubble constant using the strongly lensed gravitational wave (GW) signals. By
reparameterizing the waveform, we find that the lensed waveform is sensitive to
the . Assuming the scenario that no electromagnetic counterpart of the GW
source can be identified, our method can still give meaningful constraints on
the with the information of the lens redshift. We then apply Fisher
information matrix and Markov Chain Monte Carlo to evaluate the potential of
this method. For the space-based GW detector, TianQin, the can be
constrained within a relative error of 0.3-2\%, using a single strongly
lensed GW event. Precision varies according to different levels of
electromagnetic information.Comment: 8 pages, 4 figure
Experimental realization of quantum non-reciprocity based on cold atomic ensembles
In analog to counterparts widely used in electronic circuits, all optical
non-reciprocal devices are basic building blocks for both classical and quantum
optical information processing. Approaching the fundamental limit of such
devices, where the propagation of a single photon exhibits a good
non-reciprocal characteristic, requires an asymmetric strong coupling between a
single photon and a matter. Unfortunately it has been not realized yet. Here,
we propose and experimentally realize a quantum non-reciprocity device with low
optical losses and a high isolation of larger than 14 dB based on the cold
atoms. Besides, the non-reciprocal transmission of a quantum qubit and
non-reciprocal quantum storage of a true single photon are also realized. All
results achieved would be very promising in building up quantum non-reciprocal
devices for quantum networks.Comment: 7 pages, 4 figure
Intelligent diagnostic scheme for lung cancer screening with Raman spectra data by tensor network machine learning
Artificial intelligence (AI) has brought tremendous impacts on biomedical
sciences from academic researches to clinical applications, such as in
biomarkers' detection and diagnosis, optimization of treatment, and
identification of new therapeutic targets in drug discovery. However, the
contemporary AI technologies, particularly deep machine learning (ML), severely
suffer from non-interpretability, which might uncontrollably lead to incorrect
predictions. Interpretability is particularly crucial to ML for clinical
diagnosis as the consumers must gain necessary sense of security and trust from
firm grounds or convincing interpretations. In this work, we propose a
tensor-network (TN)-ML method to reliably predict lung cancer patients and
their stages via screening Raman spectra data of Volatile organic compounds
(VOCs) in exhaled breath, which are generally suitable as biomarkers and are
considered to be an ideal way for non-invasive lung cancer screening. The
prediction of TN-ML is based on the mutual distances of the breath samples
mapped to the quantum Hilbert space. Thanks to the quantum probabilistic
interpretation, the certainty of the predictions can be quantitatively
characterized. The accuracy of the samples with high certainty is almost
100. The incorrectly-classified samples exhibit obviously lower certainty,
and thus can be decipherably identified as anomalies, which will be handled by
human experts to guarantee high reliability. Our work sheds light on shifting
the ``AI for biomedical sciences'' from the conventional non-interpretable ML
schemes to the interpretable human-ML interactive approaches, for the purpose
of high accuracy and reliability.Comment: 10 pages, 7 figure
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