Democratization and foreign policy in Southeast Asia: the case of the ASEAN Inter-Parliamentary Myanmar Caucus

This is an Author's Accepted Manuscript of an article published in Cambridge Review of International Affairs Vol. 22, Iss. 3, 2009 as published in the CAMBRIDGE REVIEW OF INTERNATIONAL AFFAIRS, 2009, copyright Taylor & Francis, available online at: http://www.tandfonline.com/10.1080/09557570903104008

Multiple novel prostate cancer susceptibility signals identified by fine-mapping of known risk loci among Europeans

Genome-wide association studies (GWAS) have identified numerous common prostate cancer (PrCa) susceptibility loci. We have fine-mapped 64 GWAS regions known at the conclusion of the iCOGS study using large-scale genotyping and imputation in 25 723 PrCa cases and 26 274 controls of European ancestry. We detected evidence for multiple independent signals at 16 regions, 12 of which contained additional newly identified significant associations. A single signal comprising a spectrum of correlated variation was observed at 39 regions; 35 of which are now described by a novel more significantly associated lead SNP, while the originally reported variant remained as the lead SNP only in 4 regions. We also confirmed two association signals in Europeans that had been previously reported only in East-Asian GWAS. Based on statistical evidence and linkage disequilibrium (LD) structure, we have curated and narrowed down the list of the most likely candidate causal variants for each region. Functional annotation using data from ENCODE filtered for PrCa cell lines and eQTL analysis demonstrated significant enrichment for overlap with bio-features within this set. By incorporating the novel risk variants identified here alongside the refined data for existing association signals, we estimate that these loci now explain ∼38.9% of the familial relative risk of PrCa, an 8.9% improvement over the previously reported GWAS tag SNPs. This suggests that a significant fraction of the heritability of PrCa may have been hidden during the discovery phase of GWAS, in particular due to the presence of multiple independent signals within the same regio

Indonesia's Elite: Political Culture and Cultural Politics

281 hal.: 21 cm; Index; Bibliography

Power and pancaroba: Indonesia in a changing world of states. by Donald K. Emmerson

tag=1 data=Power and pancaroba: Indonesia in a changing world of states. by Donald K. Emmerson tag=2 data=Emmerson, Donald K. tag=3 data=International Journal, tag=4 data=46 tag=5 data=3 tag=6 data=Summer 1991 tag=7 data=449-474. tag=8 data=SOUTH-EAST ASIA tag=10 data=Pancaroba: Politically the term can refer, for example, to the proliferation of uncertainty - dangers alongside opportunities - in the pregnant vacuum between former and future regimes. Provided by MICAH, Canberra. tag=11 data=1992/4/5 tag=12 data=92/0281 tag=13 data=CABPancaroba: Politically the term can refer, for example, to the proliferation of uncertainty - dangers alongside opportunities - in the pregnant vacuum between former and future regimes. Provided by MICAH, Canberra

Indonesia beyond Soeharto. : Negara, ekonomi, masyarakat, transisi.

Jakartaxxvi, 678 p.; 24 cm

Indonesia in 1990: a foreshadow play. Donald K. Emmerson

Repeatedly in 1990 in foreign, political, and economic affairs, Indonesians made statements and took steps in anticipation of things to come. Provided by MICAH, Canberr

Indonesia's Elite: Political Culture and Cultural Politics

iv.80 hal.;ill.;21 c

Debating Artificial Intelligence : The Fox versus the Hedgehog

Singapore in Southeast Asia and Stanford University in the United States are focal points for discussions of AI and how it can be made to help not hurt human beings. A recent panel at Stanford illustrates the difficulty and necessity of bringing both generalist and specialist perspectives to bear on the problem

Indonesia Beyond Soeharto : Negara, Ekonomi, Masyarakat, Transisi

xxvi, 678 hlm., bibl., 23 c