Proportion of perfectly phased SNP pairs and vector error rate for RL (solid line) and MEC (dashed line) optimization in 10000 trials over 5×, 10×, 20× and 100× coverage.

<p>Proportion of perfectly phased SNP pairs and vector error rate for RL (solid line) and MEC (dashed line) optimization in 10000 trials over 5×, 10×, 20× and 100× coverage.</p

Loss of function in different polyplotypes of a sample pentaploid genome.

<p>As the loss of function is often determined by whether a healthy copy of a gene exists, knowing the genotype vector is sufficient if there is a single SNP site. In the case of two SNP sites however, the genotype vector cannot be used to unambiguously determine loss of function, and phasing is required.</p

HapTree (solid lines) and HapCompass (dashed lines) on simulated triploid genomes: Likelihood of Perfect Solution and Vector Error Rates, 1000 Trials, Block lengths: 10, 20, and 40.

<p>HapTree (solid lines) and HapCompass (dashed lines) on simulated triploid genomes: Likelihood of Perfect Solution and Vector Error Rates, 1000 Trials, Block lengths: 10, 20, and 40.</p

Examples of <i>Vector Error</i> in a sample tetraploid genome; the true phase is on the left and examples with two, three, and four vector errors are on the right.

<p>Examples of <i>Vector Error</i> in a sample tetraploid genome; the true phase is on the left and examples with two, three, and four vector errors are on the right.</p

HapTree (solid line) and HapCompass (dashed line) on simulated tetraploid genomes: Likelihood of Perfect Solution and Vector Error Rates, 1000 Trials, Block length: 10.

<p>HapTree (solid line) and HapCompass (dashed line) on simulated tetraploid genomes: Likelihood of Perfect Solution and Vector Error Rates, 1000 Trials, Block length: 10.</p

Results of switch error (switch) and MEC score for HapTree and HapCUT of whole-genome phasing using 454 and Illumina data.

<p>Results of switch error (switch) and MEC score for HapTree and HapCUT of whole-genome phasing using 454 and Illumina data.</p

HapTree performance over varied error rates (.001, .02, .05, .1) and coverages (10×, 20×, 40×) on simulated triploid genomes: Likelihood of Perfect Solution and Vector Error Rates, 10000 Trials, Block length: 10.

<p>HapTree performance over varied error rates (.001, .02, .05, .1) and coverages (10×, 20×, 40×) on simulated triploid genomes: Likelihood of Perfect Solution and Vector Error Rates, 10000 Trials, Block length: 10.</p

Table_1_A systematic review of the long-term benefits of school mental health and wellbeing interventions for students in Australia.docx

BackgroundOver the last decade there has been increased recognition about the role of school staff in preventing mental ill health and promoting wellbeing in young people. Despite this, information regarding the long-term benefits of school mental health programs is not widely available.AimsThe aim of this systematic review was to synthesize the evidence for school-based mental health and wellbeing programs which are available in Australia and have been shown to have long-term benefits for children and adolescents.ResultsThis systematic review of the literature identified 74 articles reporting long-term outcomes for student mental health and wellbeing, distributed across 29 unique programs. Common features of efficacious programs included cognitive behavioral interventions, mental health literacy, and social-emotional skills programs.ConclusionsSome of the identified school-based interventions for student mental health and wellbeing demonstrated long-term positive impacts on students' physical and psychological health and wellbeing.</p