A knowledge broken. Essay writing and human science in Montaigne and Bacon”

Literary theory and criticism over the last three decades have shown an increasing interest in studying the cognitive and critical relevance of the “essay” for modern history and culture . This paper aims to supply supporting evidence for this perspective, examining the function of essay writing for both Montaigne and Francis Bacon's conception of human thought and knowledge. In particular, I will focus on the epistemological implications of the essay and fragmentary prose, both considered forms of writing that express a particular way of thinking

« Je ne vois rien… où je me puis tenir »

L’inquiétude occupe une place capitale dans l’anthropologie montanienne des passions. Cette étude analyse les assises naturelles et les rapports avec le corps et l’âme. Face à l’inquiétude, la posture de Montaigne s’écarte de celle de ses contemporaines, tels Louis Le Caron et Pierre de Lancre, qui neutralisent ses effets dans un hors-texte théologique et providentiel. De ce fait, les Essais peuvent être envisagés comme un véritable « livre de l’inquiétude ».Anxiety occupies a central place in Montaigne’s anthropology of the passions. This study analyzes its natural foundations and its relationship with the body and the soul. Montaigne’s stance in relation to anxiety departs from that of his contemporaries, such as Louis Le Caron and Pierre de Lancre, who create a theological and providential subtext to counteract the effects of anxiety. In this light, the Essays can be considered a true “Book of anxiety”

Ce que les Essais de Montaigne nous apprennent sur la valeur cognitive et morale de la littérature

De Martha Nussbaum à Terence Cave, la critique littéraire et la théorie philosophique contemporaines s’interrogent sur la valeur cognitive et morale de la littérature. Fondant leur enquête anthropologique et morale sur un usage cognitif et pragmatique de la littérature fictionnelle et non fictionnelle, les Essais de Montaigne nous offrent un exemple marquant des rapports étroits et féconds entre la littérature, la philosophie et la vie.From Martha Nussbaum to Terence Cave, contemporary literary criticism and philosophy question the moral and cognitive value of literature. Founding their anthropological and moral investigation on a cognitive and pragmatic usage of fictional and non-fictional literature, Montaigne’s Essais offers a striking example of the productive and close relations between literature, philosophy and life

Silk reinforced with graphene or carbon nanotubes spun by spiders

Here, we report the production of silk incorporating graphene and carbon nanotubes directly by spider spinning, after spraying spiders with the corresponding aqueous dispersions. We observe a significant increment of the mechanical properties with respect to the pristine silk, in terms of fracture strength, Young's and toughness moduli. We measure a fracture strength up to 5.4 GPa, a Young's modulus up to 47.8 GPa and a toughness modulus up to 2.1 GPa, or 1567 J/g, which, to the best of our knowledge, is the highest reported to date, even when compared to the current toughest knotted fibres. This approach could be extended to other animals and plants and could lead to a new class of bionic materials for ultimate applications

Adicción a redes sociales y procrastinación académica : estudio a realizarse con estudiantes de la carrera Lic. en Enfermería de la Escuela de Enfermería – FCM – UNC, durante el segundo semestre del 2022

A lo largo del siglo XXI, y más aún en los últimos dos años, se han establecido una serie de encuentros y desencuentros entre educación y el uso de las Tics como facilitador de la misma. El aprendizaje en ámbitos formales, utilizando los nuevos cambios que introducen las tecnologías de comunicación e información (con internet como su máximo exponente), requiere de un proceso de articulación entre ambos para que la educación no sea desplazada en su protagonismo, ya que con la irrupción de éstas tecnologías se produjeron modificaciones en el proceso tradicional de enseñanza y transmisión de conocimientos. Sin embargo, gran parte de los estudiantes pueden presentar conductas inadecuadas frente al uso de las nuevas tecnologías, como el abuso del internet y la procrastinación académica. La constatación de la existencia de procrastinación académica en universitarios en relación al uso y dependencia de las TICs, no presenta hasta la fecha suficientes investigaciones, sin embargo, se empieza a vislumbrar como un problema emergente, producto de la nueva modernidad. El objetivo de este estudio es Identificar la presencia de adicción a redes sociales y procrastinación académica en los estudiantes de 5to año de la Escuela de Enfermería de la Universidad Nacional de Córdoba, durante el año 2022, con el propósitode generar conocimientos que resulten beneficiosos para todo el ámbito académico local y sea extensivo a demás instituciones educativas. El tipo de estudio a realizar será cuantitativo, descriptivo y transversal, la técnica de recolección de datos será de fuentes primarias a través de cuestionarios autoadministrados basados en los instrumentos relacionados a las variables: Adicción a Redes Sociales, donde sus dimensiones son Obsesión por las redes sociales, Falta de control personal y Uso excesivo; y Procrastinación académica que se dimensiona en la Autorregulación académica y la Postergación de actividades. La población estará compuesta por una muestra aleatoria de estudiantes de 5to año de la carrera de Licenciatura en Enfermería de la Universidad Nacional de Córdoba. El Proyecto consta de 2 capítulos: El Capítulo I: El problema de investigación, donde se encuentra la contextualización temática enmarcando Adicción a redes sociales y Procrastinación académica a nivel mundial, nacional y local. Y el Capítulo II: El Diseño Metodológico, aplicación práctica de la teoría expuesta, recolección, representación y análisis de los datos.Fil: Calderón, Florencia. Universidad Nacional de Córdoba. Facultad de Ciencias Médicas. Escuela de Enfermería; Argentina.Fil: Ducca, Emiliano. Universidad Nacional de Córdoba. Facultad de Ciencias Médicas. Escuela de Enfermería; Argentina.Fil: Ferrari, Enzo. Universidad Nacional de Córdoba. Facultad de Ciencias Médicas. Escuela de Enfermería; Argentina.Fil: Heredia, Gimena. Universidad Nacional de Córdoba. Facultad de Ciencias Médicas. Escuela de Enfermería; Argentina

Phantom validation of quantitative Y-90 PET/CT based dosimetry in liver radioembolisation

Background PET/CT has recently been shown to be a viable alternative to traditional post-infusion imaging methods providing good quality images of 90Y-laden microspheres after selective internal radiation therapy (SIRT). In the present paper, first we assessed the quantitative accuracy of 90Y-PET using an anthropomorphic phantom provided with lungs, liver, spine, and a cylindrical homemade lesion located into the hepatic compartment. Then, we explored the accuracy of different computational approaches on dose calculation, including (I) direct Monte Carlo radiation transport using Raydose, (II) Kernel convolution using Philips Stratos, (III) local deposition algorithm, (IV) Monte Carlo technique (MCNP) considering a uniform activity distribution, and (V) MIRD (Medical Internal Radiation Dose) analytical approach. Finally, calculated absorbed doses were compared with those obtained performing measurements with LiF:Mg,Cu,P TLD chips in a liquid environment. Results Our results indicate that despite 90Y-PET being likely to provide high-resolution images, the 90Y low branch ratio, along with other image-degrading factors, may produce non-uniform activity maps, even in the presence of uniform activity. A systematic underestimation of the recovered activity, both for the tumor insert and for the liver background, was found. This is particularly true if no partial volume correction is applied through recovery coefficients. All dose algorithms performed well, the worst case scenario providing an agreement between absorbed dose evaluations within 20%. Average absorbed doses determined with the local deposition method are in excellent agreement with those obtained using the MIRD and the kernel-convolution dose calculation approach. Finally, absorbed dose assessed with MC codes are in good agreement with those obtained using TLD in liquid solution, thus confirming the soundness of both calculation approaches. This is especially true for Raydose, which provided an absorbed dose value within 3% of the measured dose, well within the stated uncertainties. Conclusions Patient-specific dosimetry is possible even in a scenario with low true coincidences and high random fraction, as in 90Y–PET imaging, granted that accurate absolute PET calibration is performed and acquisition times are sufficiently long. Despite Monte Carlo calculations seeming to outperform all dose estimation algorithms, our data provide a strong argument for encouraging the use of the local deposition algorithm for routine 90Y dosimetry based on PET/CT imaging, due to its simplicity of implementation

Vicarious Learning from Human Models in Monkeys

We examined whether monkeys can learn by observing a human model, through vicarious learning. Two monkeys observed a human model demonstrating an object–reward association and consuming food found underneath an object. The monkeys observed human models as they solved more than 30 learning problems. For each problem, the human models made a choice between two objects, one of which concealed a piece of apple. In the test phase afterwards, the monkeys made a choice of their own. Learning was apparent from the first trial of the test phase, confirming the ability of monkeys to learn by vicarious observation of human models

Harmonizing neuropsychological assessment for mild neurocognitive disorders in Europe

INTRODUCTION Harmonized neuropsychological assessment for neurocognitive disorders, an international priority for valid and reliable diagnostic procedures, has been achieved only in specific countries or research contexts. METHODS To harmonize the assessment of mild cognitive impairment in Europe, a workshop (Geneva, May 2018) convened stakeholders, methodologists, academic, and non-academic clinicians and experts from European, US, and Australian harmonization initiatives. RESULTS With formal presentations and thematic working-groups we defined a standard battery consistent with the U.S. Uniform DataSet, version 3, and homogeneous methodology to obtain consistent normative data across tests and languages. Adaptations consist of including two tests specific to typical Alzheimer's disease and behavioral variant frontotemporal dementia. The methodology for harmonized normative data includes consensus definition of cognitively normal controls, classification of confounding factors (age, sex, and education), and calculation of minimum sample sizes. DISCUSSION This expert consensus allows harmonizing the diagnosis of neurocognitive disorders across European countries and possibly beyond

PTX3 Polymorphisms and Invasive Mold Infections After Solid Organ Transplant

Donor PTX3 polymorphisms were shown to influence the risk of invasive aspergillosis among hematopoietic stem cell transplant recipients. Here, we show that PTX3 polymorphisms are independent risk factors for invasive mold infections among 1101 solid organ transplant recipients, thereby strengthening their role in mold infection pathogenesis and patients' risk stratificatio