Studies of Proton Induced Neutral Pion Production Near Threshold

Supported by the National Science Foundation and Indiana Universit

Development of a Pi° Detector System

This work was supported by National Science Foundation Grants PHY 76-84033A01, PHY 78-22774, and Indiana Universit

Studies of Proton-Induced Neutral Pion Production Near Threshold

This work was supported by the National Science Foundation Grant NSF PHY 81-14339 and by Indiana Universit

Fragmentation of High-spin Particle-hole States in 26-Mg

This research was sponsored by the National Science Foundation Grant NSF PHy 87-1440

Fragmentation of High-Spin Particle-Hole States in 26-Mg

This work was supported by the National Science Foundation Grants NSF PHY 78-22774 A03, NSF PHY 81-14339, and by Indiana Universit

Changes in Optical Conductivity due to Readjustments in Electronic Density of States

Within the model of elastic impurity scattering, we study how changes in the energy dependence of the electronic density of states (EDOS) $N(\epsilon)$ around the Fermi energy $\epsilon_F$ are reflected in the frequency-dependent optical conductivity $\sigma(\omega)$. While conserving the total number of states in $N(\epsilon)$ we compute the induced changes in $\sigma(\omega)$ as a function of $\omega$ and in the corresponding optical scattering rate $1/\tau_{\rm op}(\omega)$. These quantities mirror some aspects of the EDOS changes but the relationship is not direct. Conservation of optical oscillator strength is found not to hold, and there is no sum rule on the optical scattering rate although one does hold for the quasiparticle scattering. Temperature as well as increases in impurity scattering lead to additional changes in optical properties not seen in the constant EDOS case. These effects have their origin in an averaging of the EDOS around the Fermi energy $\epsilon_F$ on an energy scale set by the impurity scattering.Comment: 13 pages, 7 figure

Fragmentation of High-Spin Particle-Hole States in 26-Mg

This work was supported by the National Science Foundation Grant NSF PHY 81-14339 and by Indiana Universit

Report on Experiment CE06: Measurements of Nuclear Reactions using Recoil Detection

This research was sponsored by the National Science Foundation Grant NSF PHY-931478

Filgotinib Demonstrates Efficacy in Rheumatoid Arthritis Independent of Smoking Status: Post Hoc Analysis of Phase 3 Trials and Claims-Based Analysis

Objectives: To assess cigarette smoking’s effects on efficacy of the preferential Janus kinase (JAK) 1 inhibitor filgotinib and drug persistence in patients with rheumatoid arthritis (RA). Methods: Efficacy in non-smokers, former smokers, and current smokers from phase 3 filgotinib trials was analyzed, including patients with inadequate response (IR) to methotrexate (MTX) or biologic disease-modifying antirheumatic drugs (bDMARDs) or who were MTX-naïve. Proportions achieving Disease Activity Score in 28 joints with C-reactive protein (DAS28[CRP]) ≤ 3.2 were compared using logistic regression. Retrospective claims-based switching data were reviewed. Results: Week 12 (W12) DAS28(CRP) ≤ 3.2 was achieved by 50, 61, and 62% of MTX-IR non-smokers, former smokers, and current smokers taking filgotinib 200 mg (FIL200) + MTX vs. 23, 16, and 32% taking placebo + MTX (p < 0.001, < 0.001, and 0.001) and 50, 34, and 33% taking adalimumab + MTX (p = 0.97, 0.013, and 0.006 vs. FIL200 + MTX). W12 DAS28(CRP) ≤ 3.2 was achieved by 46, 48, and 32% of bDMARD-IR non-smokers, former smokers, and current smokers taking FIL200 + conventional synthetic disease-modifying antirheumatic drugs (csDMARDs) vs. 16, 23, and 5% taking placebo + csDMARD (p < 0.001, 0.077, and 0.051); 57, 58, and 59% of respective MTX-naïve smoking groups achieved W12 DAS28(CRP) ≤ 3.2 with FIL200 + MTX vs. 28, 37, and 18% with MTX (p < 0.001, 0.026, and < 0.001). Claims data showed former/current smokers were likelier than non-smokers to switch from adalimumab to other biologics or JAK inhibitors. Conclusions: Greater proportions of MTX-IR current/former smokers responded to FIL200 + MTX vs. adalimumab + MTX. In non-smoking MTX-IR, bDMARD-IR, and MTX-naïve patients with RA, FIL200 + MTX demonstrated increased response vs. controls. Current/former smokers were likelier to discontinue adalimumab vs. non-smokers in real-world clinical settings. Trial Registration: NCT02889796, NCT02873936, NCT02886728

Fluctuating diamagnetism in underdoped high temperature superconductors

The fluctuation induced diamagnetism of underdoped high temperature superconductors is studied in the framework of the Lawrence-Doniach model. By taking into account the fluctuations of the phase of the order parameter only, the latter reduces to a layered XY-model describing a liquid of vortices which can be either thermally excited or induced by the external magnetic field. The diamagnetic response is given by a current-current correlation function which is evaluated using the Coulomb gas analogy. Our results are then applied to recent measurements of fluctuation diamagnetism in underdoped YBCO. They allow to understand both the observed anomalous temperature dependence of the zero-field susceptibility and the two distinct regimes appearing in the magnetic field dependence of the magnetization.Comment: 12 pages, 4 figures included, accepted for publication in PR