Mortality causes in goldsmiths of Bangladesh: Findings from verbal autopsy

Background: Information on the mortality causes of goldsmiths in Bangladesh is limited. This study aimed to find out the mortality causes in a selected group of goldsmiths. Methods: A World Health Organization recommended questionnaire was adapted to conduct verbal autopsy of 20 deceased goldsmiths. Death-related information was gathered from the family members present during deceased’s illness preceding death. The mortality causes were determined by the interview outcomes and medical records-review. Results: The mean age of the goldsmiths at death was 59.2± 9.3 years. Among then, 70.0% were smokers and 50.0% were alcohol consumers. Cardiovascular diseases (CVD) were the most common immediate and underlying cause of death (60.0% and 45.0%, respectively). Conclusion: The life expectancy of goldsmiths was much lower than the average life expectancy of Bangladeshi population, where CVD was the primary cause of death. Smoking and alcohol consumption were prevalent among them. Awareness about healthy lifestyles should be prioritized for highly CVD prevention among the goldsmiths.  Bangabandhu Sheikh Mujib Medical University Journal 2023;16(2): 87-9

Types and distribution of cancer patients attending in a tertiary care hospital of Bangladesh

Bangladesh, similar to other countries is experiencing an increased burden of cancer. Absence of a national cancer registry has created a gap in the information regarding the presentation of cancer statistics of the country. The objective of this study was to assess the types and distribution of the cancer patients attending a tertiary academic medical center hospital in Bangladesh. A cross-sectional study was conducted among all the confirmed cancer patients attending the in-patient and out-patient, and daycare facilities in Bangabandhu Sheikh Mujib Medical University in October, 2019. A validated questionnaire, recommended by International Agency for the Cancer Registry was used to collect data. Written informed consent was obtained from every respondent. This study had received its ethical clearance from Institutional Review Board of BSMMU. Among the 1656 respondents, 78.8% were adult and 25.2% were from paediatric age groups. Leading cancer for adult males were lung cancer (9.6%), leukaemia (9.4%) and lymphoma (9.0%); and breast cancer (28.1%), thyroid cancer (16.1%), and cervical cancer (12.2%) for females. Leukaemia was the most frequent cancer in the paediatric group for both males (71.5%) and females (66.5%). Establishing a hospital-based cancer registry with high quality data in an academic medical center setting is feasible and can set the stage for establishing nationwide hospital-based as well as establishing a popula- tion-based cancer registry in Bangladesh, which is necessary to identify and tackle the rising burden of cancer in this country. BSMMU J 2022; 15(1): 43-4

Comparative genomics of two jute species and insight into fibre biogenesis

Jute (Corchorus sp.) is one of the most important sources of natural fibre, covering ∼80% of global bast fibre production1. Only Corchorus olitorius and Corchorus capsularis are commercially cultivated, though there are more than 100 Corchorus species2 in the Malvaceae family. Here we describe high-quality draft genomes of these two species and their comparisons at the functional genomics level to support tailor-designed breeding. The assemblies cover 91.6% and 82.2% of the estimated genome sizes for C. olitorius and C. capsularis, respectively. In total, 37,031 C. olitorius and 30,096 C. capsularis genes are identified, and most of the genes are validated by cDNA and RNA-seq data. Analyses of clustered gene families and gene collinearity show that jute underwent shared whole-genome duplication ∼18.66 million years (Myr) ago prior to speciation. RNA expression analysis from isolated fibre cells reveals the key regulatory and structural genes involved in fibre formation. This work expands our understanding of the molecular basis of fibre formation laying the foundation for the genetic improvement of jute. Bast (phloem) fibres are obtained from the stem of the plants such as jute, flax, hemp, ramie and kenaf. The annual global production of jute generates a farm value of ∼US$2.3 billion1. The cultivated species of jute, C. olitorius and C. capsularis, are morphologically and physiologically distinct (Supplementary Fig. 1), and a combination of useful traits from these species into a single genotype is highly desirable3. However, interspecific hybridization is limited because of their cross-incompatibility4,5. To facilitate comparative functional genomics and to understand the molecular basis of bast fibre biogenesis, genomes of two popular jute cultivars C. olitorius var. O-4 and C. capsularis var. CVL-1 are sequenced and analysed

Shades of grey:risk-related agency conflicts and corporate innovation

We investigate how risk-related agency conflicts affect valuable risky investments. Using an exogenous negative shock to shareholders' litigation rights from an unanticipated court ruling that exacerbates risk-related agency conflicts by shielding managers from shareholders' governance through litigation, we show that innovation inputs and quality decline significantly for treated firms. Small firms lacking counteracting governance mechanisms, such as institutional investors, suffer significantly, while large firms with high institutional investments emerge unscathed. Our results are consistent with theories that predict managerial incentives for ‘playing safe’ lead to value-destroying and risk-reducing actions, especially when counteracting incentive mechanisms are muted.</p

Climate Variability, Dengue Vector Abundance and Dengue Fever Cases in Dhaka, Bangladesh: A Time-Series Study

Numerous studies on climate change and variability have revealed that these phenomena have noticeable influence on the epidemiology of dengue fever, and such relationships are complex due to the role of the vector—the Aedes mosquitoes. By undertaking a step-by-step approach, the present study examined the effects of climatic factors on vector abundance and subsequent effects on dengue cases of Dhaka city, Bangladesh. Here, we first analyzed the time-series of Stegomyia indices for Aedes mosquitoes in relation to temperature, rainfall and relative humidity for 2002–2013, and then in relation to reported dengue cases in Dhaka. These data were analyzed at three sequential stages using the generalized linear model (GLM) and generalized additive model (GAM). Results revealed strong evidence that an increase in Aedes abundance is associated with the rise in temperature, relative humidity, and rainfall during the monsoon months, that turns into subsequent increases in dengue incidence. Further we found that (i) the mean rainfall and the lag mean rainfall were significantly related to Container Index, and (ii) the Breteau Index was significantly related to the mean relative humidity and mean rainfall. The relationships of dengue cases with Stegomyia indices and with the mean relative humidity, and the lag mean rainfall were highly significant. In examining longitudinal (2001–2013) data, we found significant evidence of time lag between mean rainfall and dengue cases

Discourse of Flood Management Approaches and Policies in Bangladesh: Mapping the Changes, Drivers, and Actors

The fundamental processes of policy shifts emphasize how policy problems emerge and how policy decisions are made to overcome previous shortcomings. In Bangladesh, flood management policies may also have been driven by policy failures and flood-disaster events. In this context, we examined how policy shifts occurred in the country from 1947 to 2019 in areas of water management and flood prevention, control, and risk mitigation. To understand the nature of these policy shifts, we examined the evolutionary processes of flood management policies, the associated drivers, and the roles of key actors. Our findings reveal that policy transitions were influenced primarily by the predominance of the structural intervention paradigm and by catastrophic flood events. Such transitions were nonlinear due to multiple interest groups who functioned as contributors to, as well as barriers against, flood prevention policies. Policy debates over environmental concerns helped bring about a shift from a primary focus on structural intervention to a mixed approach incorporating various nonstructural interventions. Furthermore, our results suggest that the shifts in flood management policies have resulted in some degree of reliance on a &ldquo;people-centered&rdquo; approach rather than solely an &ldquo;engineering coalition&rdquo;, which emphasizes the pivotal role of community members in decision making and the implementation of flood policies and programs

Social learning-based disaster resilience : collective action in flash flood-prone Sunamganj communities in Bangladesh

Despite widespread recognition that social learning can potentially contribute toward enhancing community resilience to climate-induced disaster shocks, studies on this process remain few and far between. This study investigates the role of local institutions (formal, informal, and quasi-formal) in creating learning arenas and translating social learning into collective action in flash flood-prone Sunamganj communities in Bangladesh. We follow a Case Study approach using qualitative research methods. Primary data were collected through 24 key informant interviews, 10 semi-structured interviews, six focus-group discussions, and two participant observations events. Our results reveal that the diversity and flexibility of local-level institutions creates multiple learning platforms in which social interaction, problem formulation, nurturing diverse perspectives, and generating innovative knowledge for collective action can take place. Within these formal and informal learning arenas, communities’ desire and willingness to be self-reliant and to reduce their dependency on external funding and assistance is clearly evident. Social learning thus paves the way for institutional collaboration, partnership, and multi-stakeholder engagement, which facilitates social learning-based collective action. Nurturing institutional diversity and flexibility at the local level is therefore recommended for transforming social learning into active problem-solving measures and to enhance community resilience to disaster shocks.Social Science and Humanities Research Council (SSHRC), Ottawa, Canad

Jute CDPK genes and their role in stress tolerance and fiber development: a\ua0genome-wide bioinformatic investigation of Chorchorus capsularis and C. olitorius

Calcium-dependent protein kinases (CDPKs) are plant-specific calcium sensors, which regulate plant growth and development and induce protective responses to environmental stresses. To date, no information on jute\ua0CDPKs\ua0is available and their uses in the genetic improvement program is underutilized. In this study, we exploited recently available genome sequence information of two jute species:\ua0Corchorus olitorius\ua0and\ua0C. capsularis\ua0to identify, characterise, and functional analysis. Using bioinformatics tools, 16 and 18\ua0CDPK\ua0genes with serine/threonine protein kinase along with EF-hand calcium-binding domain were identified from the genomes of\ua0C. olitorius\ua0and\ua0C. capsularis,\ua0respectively. Different chromosomes harboured different\ua0CDPK\ua0genes. Four distinct clades of\ua0CDPK\ua0genes were identified by phylogenetic analysis. Protein of each clade showed higher conservation in length, structure, and presence of motif. The most prominent transcriptional responses were detected in saline and drought conditions where more than half of the\ua0CDPKs were upregulated, suggesting their important roles in abiotic stress responses of jute. Specifically,\ua0CoCDPK6, 11, 12, and their corresponding homologs\ua0CcCDPK18, 10, 8 were highly expressed in saline and drought conditions. On the other hand,\ua0CoCDPK6, 7, 11, 12, and their homologs\ua0CcCDPK18, 17, 10, 8 were highly expressed in fiber cell indicating their involvement in fiber cell development. Our results provide an important foundation for further functional dissection of\ua0CDPKs of\ua0C. olitorius\ua0and\ua0C. capsularis\ua0for salinity and drought stress adaptation and fiber quality improvement

Effects of Yarn, Fabric and Machine Parameters on the Dimensional Properties of Weft Knitted Single Jersey Fabric

Weft knit fabrics are popular for traditional wear because of their elastic and light structures, gentle smoothness, low production costs, and high productivity. However, due to asymmetrical loop formation, spirality causes serious dimensional problems in single jersey fabrics (SJF). This study investigates the effects of various parameters on spirality, including yarn count, yarn tension, tightness factor, stitch length, fabric weight per unit area, machine speed, needle gauge, and number of feeders. All the sample fabrics were knitted with Z-twisted, combed, 100% cotton yarns and went through a scouring, bleaching, and whitening process before being dried in the same conditions. Fabric spirality was found to increase as stitch length, number of feeders, yarn count, and twists per unit length in constituent yarn increased whereas the tightness factor and needle gauge, on the other hand, had opposite effects on spirality. The test results were analyzed statistically, and a significant impact was discovered