STATE OF ART ON TRANSCATHETER AORTIC VALVE IMPLANTATION (TAVI) FOR THE TREATMENT OF AORTIC STENOSIS

Transcatheter Aortic Valve Implantation (TAVI) technique represents a real revolution in the field of interventional cardiology and medicine, in particularly for the treatment of aortic valve stenosis in elderly patients, or in patients when the periprocedural risk for the traditional surgical option is considered too high, as an alternative to the traditional aortic valve replacement. From the year 2002, when Cribier, in France, performed the first transcatheter aortic valve implantation (TAVI), in a period of just over a decade, this technique has become a reality in clinical practice of cardiologists interventionists worldwide. The data of follow-up in the long term are currently available mainly for the valves of the first generation. These data show an excellent, also at long term, hemodynamic performance. Although experience on the valves of the last generation is still limited in time, the data currently available are definitely in the direction of a minimum hospital mortality (1%), as well as to a drastic reduction in the incidence of complications, compared to the devices of the previous generation. Finally, the evolution of specified materials of the newest generation have greatly enhanced safety and efficacy of TAVI procedures in the last year

Coronary tortuosity: normal variant or pathological condition?

HighlightsCoronary tortuosity is a common coronary angiography finding. The aetiology and the clinical significant are not well defined, generally considered a normal variant. We showed a case of marked tortuosity of all coronary arteries associated with myocardial ischemia. </p

percutaneous approach to a tight post isthmic aortic coarctation a case report and literature review

Correction: Figure 1 and Figure 2 were omitted from the PDF. On 5th June 2017, the new PDF including the figures was uploaded and the page numbers of the article changed from 41-44 TO 41-45.A 17 years-old boy with hypertension underwent cardiology assessment for episodes of dyspnoea and palpitations. Cardiac angiography showed post-istmic severe aortic coarctation. The malformation was successful treated by implanting a covered stent in aorta. The manuscript describes in detail this case and analyzes the available literature on the topic.Journal of Advances in Internal Medicine Vol.5(2) 2016: 41-4

Accuracy of Intravascular Ultrasound Evaluation for the Assessment of Native Valve Measures in Patients Undergoing TAVI: Preliminary Results

Transcatheter aortic valve implantation (TAVI) technique represents a real revolution in the field of interventional cardiology and medicine, in particular for the treatment of severe aortic valve stenosis in elderly patients or in patients when the periprocedural risk for the traditional surgical option is considered too high, as an alternative to the traditional aortic valve replacement. Although experience on the valves of the last generation is still limited in terms of time, the data currently available are definitely moving in the direction of a minimum hospital mortality (1%) as well as a drastic reduction in the incidence of complications when compared to the devices of the previous generation. Finally, the evolution of specified materials of the newest generation have greatly enhanced safety and efficacy of TAVI procedures in the last years. In order to ensure the selection of the most appropriate valve and the success of the procedure, the role of cardiac imaging (computed tomography scan evaluation and angiography) is crucial. These examinations require the use of contrast medium in patients suffering from renal dysfunction at the baseline. The need for fluoroscopy and angiography using contrast agents to aid positioning of the valve may lead to contrast-induced nephropathy (CIN) as one form or one etiology of acute kidney injury (AKI), which is associated with increased morbidity and mortality. The aim of our study is to investigate the accuracy of intravascular ultrasound (IVUS-a technique which does not need contrast) for the assessment of native valve measures in patients undergoing TAVI by comparing values obtained with IVUS to those ones previously obtained in the same patients with computed tomography (CT) scans

Modulation of kinins tissue system through pulsatile antagonism of BK2 receptors confers the most effective kinin-dependent postconditioning cardioprotection

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