Additional file 1: of Association between troponin-I levels and outcome in critically ill patients admitted to non-cardiac intensive care unit with high prevalence of cardiovascular risk factors

Table S1. Categories of main reasons of ICU admission. Table S2. Baseline characteristics of the four troponin-I groups based on troponin-I measured in the first 24 h. Table S3. Multivariate analysis of the four troponin-I groups and different clinical outcomes based on troponin-I measured in the first 24-h. Table S4. Subgroup analysis for the association between different levels of troponin-I measured in the first 24 h (all compared to Group I as a reference) and hospital mortality. The following variables were used as covariates in the model: age, APACHE II, sex, admission diagnosis, diabetes, chronic liver disease, chronic respiratory disease, chronic renal diseases, chronic immunosuppression, vasopressor use, sepsis, cardiac arrest, acute kidney injury, Glasgow Coma Scale, platelet, INR, bilirubin and lactic acid levels) Interaction test was performed for each subgroup. (DOCX 45 kb

Minimal underlying data.

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Outcomes.

Outcomes.</p

Change of daily process measures over the study period among the whole cohort and in subgroups of ICUs with baseline spontaneous trial (SAT) compliance of >50% and ≤50.

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Map of Saudi Arabia with distribution of participating ICUs.

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Distribution of compliance, non-compliance and contraindications (with reasons) to the interventions.

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List of participating sites and ethics committee approvals.

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Data measures definitions.

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Characteristics of participating sites.

IQR: interquartile range. (PDF)</p

CONSORT 2010 checklist of information to include when reporting a randomised trial*.

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