1,005 research outputs found
The 15-meter diameter hoop/column antenna surface control actuator system
The design, development, and implementation status of the Surface Control Actuator System (SCAS) for the Hoop/Column Antenna are described with the primary focus on the design of the mechanical element. The SCAS is an electromechanical system that will automatically adjust the antenna shape by changing the length of control cords. Achieving and maintaining the proper surface shape and smoothness are critical to optimizing the electromagnetic characteristics of the antenna
MS 082 Guide to Elvin L. Shelton, Jr., MD Papers (1948-1990)
The Elwin L. Shelton, Jr., MD papers consists largely of materials related to his professional life, such as presentations and publications, published and unpublished papers, and accreditations. There are copies of Medical Director\u27s Notebook from 1957-1960. There are also materials on topics such as philosophy, hypnosis, intestinal by-pass, GI, breast, and peritoneal dialysis research. Some items pertain to the Texas Surgical Society, Southern Society of Clinical Surgeons, and Houston Gastroenterological Society. The collection ranges in dates from 1948-1990. See more at MS 082
Surface control system for the 15 meter hoop-column antenna
The 15-meter hoop-column antenna fabricated by the Harris Corporation under contract to the NASA Langley Research Center is described. The antenna is a deployable and restowable structure consisting of a central telescoping column, a 15-meter-diameter folding hoop, and a mesh reflector surface. The hoop is supported and positioned by 48 quartz cords attached to the column above the hoop, and by 24 graphite cords from the base of the antenna column. The RF reflective surface is a gold plated molybdenum wire mesh supported on a graphite cord truss structure which is attached between the hoop and the column. The surface contour is controlled by 96 graphite cords from the antenna base to the rear of the truss assembly. The antenna is actually a quadaperture reflector with each quadrant of the surface mesh shaped to produce an offset parabolic reflector. Results of near-field and structural tests are given. Controls structures and electromagnetics interaction, surface control system requirements, mesh control adjustment, surface control system actuator assembly, surface control system electronics, the system interface unit, and control stations are discussed
Deep Statistical Solver for Distribution System State Estimation
Implementing accurate Distribution System State Estimation (DSSE) faces
several challenges, among which the lack of observability and the high density
of the distribution system. While data-driven alternatives based on Machine
Learning models could be a choice, they suffer in DSSE because of the lack of
labeled data. In fact, measurements in the distribution system are often noisy,
corrupted, and unavailable. To address these issues, we propose the Deep
Statistical Solver for Distribution System State Estimation (DSS), a deep
learning model based on graph neural networks (GNNs) that accounts for the
network structure of the distribution system and for the physical governing
power flow equations. DSS leverages hypergraphs to represent the
heterogeneous components of the distribution systems and updates their latent
representations via a node-centric message-passing scheme. A weakly supervised
learning approach is put forth to train the DSS in a learning-to-optimize
fashion w.r.t. the Weighted Least Squares loss with noisy measurements and
pseudomeasurements. By enforcing the GNN output into the power flow equations
and the latter into the loss function, we force the DSS to respect the
physics of the distribution system. This strategy enables learning from noisy
measurements, acting as an implicit denoiser, and alleviating the need for
ideal labeled data. Extensive experiments with case studies on the IEEE 14-bus,
70-bus, and 179-bus networks showed the DSS outperforms by a margin the
conventional Weighted Least Squares algorithm in accuracy, convergence, and
computational time, while being more robust to noisy, erroneous, and missing
measurements. The DSS achieves a competing, yet lower, performance compared
with the supervised models that rely on the unrealistic assumption of having
all the true labels.Comment: 10 pages, manuscript is under revie
A murine herpesvirus closely related to ubiquitous human herpesviruses causes T-cell depletion
ABSTRACT
The human roseoloviruses human herpesvirus 6A (HHV-6A), HHV-6B, and HHV-7 comprise the
Roseolovirus
genus of the human
Betaherpesvirinae
subfamily. Infections with these viruses have been implicated in many diseases; however, it has been challenging to establish infections with roseoloviruses as direct drivers of pathology, because they are nearly ubiquitous and display species-specific tropism. Furthermore, controlled study of infection has been hampered by the lack of experimental models, and until now, a mouse roseolovirus has not been identified. Herein we describe a virus that causes severe thymic necrosis in neonatal mice, characterized by a loss of CD4
+
T cells. These phenotypes resemble those caused by the previously described mouse thymic virus (MTV), a putative herpesvirus that has not been molecularly characterized. By next-generation sequencing of infected tissue homogenates, we assembled a contiguous 174-kb genome sequence containing 128 unique predicted open reading frames (ORFs), many of which were most closely related to herpesvirus genes. Moreover, the structure of the virus genome and phylogenetic analysis of multiple genes strongly suggested that this virus is a betaherpesvirus more closely related to the roseoloviruses, HHV-6A, HHV-6B, and HHV-7, than to another murine betaherpesvirus, mouse cytomegalovirus (MCMV). As such, we have named this virus murine roseolovirus (MRV) because these data strongly suggest that MRV is a mouse homolog of HHV-6A, HHV-6B, and HHV-7.
IMPORTANCE
Herein we describe the complete genome sequence of a novel murine herpesvirus. By sequence and phylogenetic analyses, we show that it is a betaherpesvirus most closely related to the roseoloviruses, human herpesviruses 6A, 6B, and 7. These data combined with physiological similarities with human roseoloviruses collectively suggest that this virus is a murine roseolovirus (MRV), the first definitively described rodent roseolovirus, to our knowledge. Many biological and clinical ramifications of roseolovirus infection in humans have been hypothesized, but studies showing definitive causative relationships between infection and disease susceptibility are lacking. Here we show that MRV infects the thymus and causes T-cell depletion, suggesting that other roseoloviruses may have similar properties.
</jats:p
Recommended from our members
Reinforced composite flywheels and shafts
The maximum safe operating speed or flywheels and shafts made of low tensile strength material is often determined by the speed at which radial tensile stress exceeds a radial tensile stress limit for the material. Circumferentially wound fiber composite material, for example, has a relatively low tensile strength along the radial direction perpendicular to the fibers. To increase the maximum safe operating speed, it is therefore desirable to form a fiber composite flywheel or shaft with radial compressive prestress. Such a prestressed flywheel or shaft has an outer annulus and an inner cylinder disposed in the outer annulus, and an annular layer of solidified bonding agent within an annular region between the outer annulus and the inner cylinder, wherein the outer annulus and the inner cylinder include substantial radial prestress induced by the bonding agent. The rim portion of a flywheel, for example, is formed from an outer ring (the annulus) and an inner ring (the cylinder, which is hollow in this case). Large, thick flywheels preferably have multiple cylindrical sections joined by such layers of bonding agent, and a plurality of the cylindrical sections each including an outer layer of relatively stiff fiber-composite material, and an inner layer of relatively compliant fiber-composite material within an integral matrix material.Board of Regents, University of Texas Syste
- …