Platelet reactivity related to macrophage levels.

<p>Comparison of the AUC after ADP stimulation between low (n = 67) versus high macrophage levels in atherosclerotic carotid plaques (n = 24). Grey bars represent means with standard deviations. MFI = mean fluorescence intensity, AUC = area under curve, ADP = adenosine diphosphate.</p

Histology of macrophage levels in atherosclerotic carotid plaques.

<p>Macrophage staining (brown), nucleus staining with haematoxylin (blue). (<b>a</b>) Low macrophage levels (40× magnification). (<b>b</b>) Higher magnification of the indicated area in (a) (100× magnification). (<b>c</b>) High macrophage levels (40× magnification). (<b>d</b>) Higher magnification of the indicated area in (c) (100× magnification).</p

Conversion of dose-response curve into area under the curve.

<p>In order to compare total platelet reactivity between patients, we derived the area under the curve from each dose response curve. MFI = mean fluorescence intensity, AUC = area under curve, ADP = adenosine diphosphate.</p

Baseline characteristics.

<p>Continuous values are expressed as mean ± standard deviation (unless specified otherwise). Categorical values are expressed as number of total (percentage).</p><p>CG = Cockroft-Gault, CEA = carotid endarterectomy, IQR = interquartile range.</p

Platelet reactivity related to platelet-monocyte complexes.

<p>Comparison of the AUC after ADP stimulation between low (n = 122) versus high levels of platelet-monocyte complexes (n = 122). Grey bars represent medians with interquartile ranges. MFI = mean fluorescence intensity, AUC = area under curve, ADP = adenosine diphosphate.</p