The Ax of Gilgamesh: Splitting Naure and Culture

The first volume of four issues addressing nature and its cultural expression. Contributors include: J.R. McNeil, Sharif S. Elmusa, Robert Switzer, E.M. Sartain, Maysa Abou-Youssef Yaywardhttps://fount.aucegypt.edu/faculty_book_chapters/2032/thumbnail.jp

Introduction

The fourth of four volumes, this volume covers resource problems in the Middle East. Contributors include: Amita Baviskar, Ana E. Cascao, Ibrahim Elnur, Robert Mabro, Greg Muttitt, MOhamed Suliman, Richard N. Tutwiler.https://fount.aucegypt.edu/faculty_book_chapters/2046/thumbnail.jp

The Ecological Bedouin: Toward Environmental Principles for the Arab Region / البدوي البيئي: نحو مبادئ بيئية للمنطقة العربية

[This article introduces a previously unexamined figure — the Ecological Bedouin (itself a take on the Ecological Indian ) — in three Arabic desert novels by Ibrahim Al-Koni, Abd al-Rahman Munif, and Sabri Moussa. The author sets up three encounters between the Ecological Bedouin and other figure types: the Bedouin of Ibn Khaldun\u27s Muqaddima, the Ecological Indian, and city interlopers. Conclusions are drawn from these encounters as to the historical circumstances of the appearance of this figure in Arabic literature, the empirical validity of the figure, and his relevance to ecological principles in the Arab region. تقيّم هذه المقالة شخصية مجازية لم تُدرَس من قبل وهي شخصية «البدوي البيئي» - التي هي بدورها تبنﹴ لمفهوم «الهندي البيئي» - في ثلاثة «روايات صحراء» عربية، للكُتاب إبراهيم الكوني، وعبد الرحمن منيف، وصبري موسى. يعقد الكاتب ثلاثة «لقاءات» بين البدوي البيئي وشخصيات أخرى: البدوي في مقدمة ابن خلدون، الهندي البيئي، والدخلاء على الصحراء من أهل الحضر. وتتوصل المقالة، بناء على هذه اللقاءات، إلى استنتاجات عن الظروف التاريخية لظهور هذه الشخصية في الأدب العربي، ومدى تطابقها مع الواقع، وصلتها بمبادئ بيئية للمنطقه العربية .

Chance Favors the Prepared Mind: Oil and Water Wars in the Middle East

The fourth of four volumes, this volume covers resource problems in the Middle East. Contributors include: Amita Baviskar, Ana E. Cascao, Ibrahim Elnur, Robert Mabro, Greg Muttitt, MOhamed Suliman, Richard N. Tutwiler.https://fount.aucegypt.edu/faculty_book_chapters/2053/thumbnail.jp

Introduction

The first volume of four issues addressing nature and its cultural expression. Contributors include: J.R. McNeil, Sharif S. Elmusa, Robert Switzer, E.M. Sartain, Maysa Abou-Youssef Yaywardhttps://fount.aucegypt.edu/faculty_book_chapters/2030/thumbnail.jp

One-pot three-component synthesis of novel pyrazolo-acridine derivatives and assessment of their acetylcholinesterase inhibitory properties: An in vitro and in silico study

In this study, the synthesis and characterization of newly designed compounds containing pyrazole, acridine, and benzothiazole groups with their biological activity potentials were evaluated. For this purpose, the starting compound of our study, 1-(benzo[d]thiazol-2-yl)-3-(4-chlorophenyl)-1H-pyrazole-4-carbaldehyde (4), was synthesized according to the Vilsmeier-Haack method. Afterward, a series of new pyrazolo-acridine derivatives (7a-l) were obtained as a result of one-pot three-component reaction of compound 1 with 5,5-dimethyl cyclohexane-1,3?dione and various aromatic amines. The structures of the synthesized compounds were characterized using FT-IR, 1H NMR, 13C NMR, Mass spectroscopy techniques, and elemental analysis. Then, the enzyme inhibition effects of these compounds on acetylcholinesterase (AChE) were investigated. According to the in vitro AChE enzyme activity studies, the most effective inhibitions of the compounds 7f (0.76±0.19 µM), 7d (0.82±0.33 µM), and 7e (1.70±1.66 µM) were determined from their low Ki values. On the other hand, in silico molecular docking interactions of the respective compounds with AChE (pdb id: 4EY9) were carried out by using AutoDock Vina software. The molecular docking analyses showed the effective molecular interactions of all compounds (7a-7l) with the AChE enzyme from their low binding energy values. © 2022 Elsevier B.V.2016-87; Çankiri Karatekin ÜniversitesiThis research has been supported by Kütahya Dumlupınar University Scientific Research Projects Coordination Office under grant number 2016-87. Also, authors would like to thank Cankırı Karatekin University for providing spectroanalytical facilities and Kütahya Dumlupınar University, Faculty of Arts and Sciences, Department of Physics for FT-IR measurements.This research has been supported by Kütahya Dumlupınar University Scientific Research Projects Coordination Office under grant number 2016-87 . Also, authors would like to thank Cankırı Karatekin University for providing spectroanalytical facilities and Kütahya Dumlupınar University, Faculty of Arts and Sciences, Department of Physics for FT-IR measurements

Vital Attitude of the Poet: Interview with Naomi Shihab Nye / ﺍﻟﻤﻮﻗﻒ ﺍﻟﺤﻴﻮﻱ ﻟﻠﺸﻌﺮﺍﺀ: ﻣﻘﺎﺑﻠﺔ ﻣﻊ ﻧﻌﻮﻣﻲ ﺷﻬﺎﺏ ﻧﺎﻱ

[This interview with poet Naomi Shihab Nye explores how her poems are informed by an inquisitive, child-like spirit and an ever-watchful eye of a mother. Such \u27vital attitude\u27 uniquely enables her to write poetry for all ages. It has also propelled her to travel across the United States and five continents, teaching the craft of poetry, and inviting audiences to experience how poems possess the power to connect people, to illuminate the mysteries of things, and to avail us of moments for self-restoration. ﺗﺴﺘﻜﺸﻒ ﻫﺬﻩ ﺍﻟﻤﻘﺎﺑﻠﺔ ﻣﻊ ﺍﻟﺸﺎﻋﺮﺓ ﻧﻌﻮﻣﻲ ﺷﻬﺎﺏ ﻧﺎﻱ ﻛﻴﻔﻴﺔ ﺗَﺸَﻜﱡﻞ ﻗﺼﺎﺋﺪﻫﺎ ﺍﻟﺘﻲ ﺗﻐﻠﺐ ﻋﻠﻴﻬﺎ ﺭﻭﺡ ﺣﺐ ﺍﺳﺘﻄﻼﻉ ﻃﻔﻮﻟﻴﺔ، ﻭﻋﻴﻦ ﺃﻡ ﻳﻘﻈﺔ٠ﻫﺬﺍ ﺍﻟﻤﻮﻗﻒ ﺍﻷﺳﺎﺳﻲ ﻟﻠﺸﺎﻋﺮﺓ ﻳﻌﻄﻴﻬﺎ ﻗﺪﺭﺓ ﻓﺮﻳﺪﺓ ﻋﻠﻰ ﻛﺘﺎﺑﺔ ﺷﻌﺮ ﻟﻜﻞ ﺍﻷﺟﻴﺎﻝ٠ ﻛﻤﺎ ﻳﺪﻓﻌﻬﺎ ﺫﺍﺕ ﺍﻟﻤﻮﻗﻒ ﺃﻥ ﺗﺠﻮﻝ ﺃﻧﺤﺎﺀ ﺍﻟﻮﻻﻳﺎﺕ ﺍﻟﻤﺘﺤﺪﺓ ﻭﺍﻟﻌﺎﻟﻢ ﻟﺘُﻌﻠﱢﻢ ﺻﻨﻌﺔ ﺍﻟﺸﻌﺮ، ﺩﺍﻋﻴﺔ ﺍﻟﺤﻀﻮﺭ ﺃﻥ ﻳﺨﺘﺒﺮﻭﺍ ﻗﺪﺭﺓ ﺍﻟﻘﺼﺎﺋﺪ ﻋﻠﻰ ﺧﻠﻖ ﺍﻟﺘﻮﺍﺻﻞ ﺑﻴﻦ ﺍﻟﻨﺎﺱ، ﻭﺇﻧﺎﺭﺓ ﺧﻔﺎﻳﺎ ﺍﻷﺷﻴﺎﺀ، ﻭﺗﻬﻴﺌﺔ ﻟﺤﻈﺎﺕ ﻻﺳﺘﻌﺎﺩﺓ ﺍﻟﻨَﻔْﺲ٠