850 research outputs found
A major role for intestinal epithelial nucleotide oligomerization domain 1 (NOD1) in mediating host bactericidal activity against Campylobacter jejuni
Perbandingan Pembelajaran Metode Praktikum Berbasis Keterampilan Proses dan Metode Praktikum Biasa terhadap Prestasi Belajar Siswa
Tujuan dari penelitian ini adalah untuk mengetahui pembelajaran metode praktikum berbasis keterampilan proses lebih baik dibandingkan dengan metode praktikum biasa terhadap hasil belajar siswa SMPN 2 Montasik.. Penelitian ini menggunakan metode eksperimen dengan pendekatan kuantitatif. Subjek penelitian ini adalah siswa kelas IX1 dan IX2 SMP 2 Montasik. Sampel penelitian ini diperoleh dari kelas IX1 dan IX2 dengan jumlah 36 siswa. Teknik pengumpulan data berupa tes yang dilakukan secara objektif terhadap aspek yang akan diamati berupa data. Alat pengumpulan data berupa soal. Indikator kinerja diharapkan yaitu siswa dapat meningkat prestasi belajar dengan menggunakan metode praktikum berbasis keterampilan proses. Hasil penelitian menunjukkan, bahwa nilai rata-rata siswa kelas eksperimen = 75,05 dan nilai siswa kelas kontrol = 66. Dengan demikian terlihat bahwa metode praktikum berbasis keterampilan proses lebih baik dari pada metode praktikum biasa.Kata Kunci : Prestasi belajar, metode, keterampilan proses, praktikum AbstrackThe purpose of this study was to determine the learning process skills-based lab method is better than the usual practical method for learning outcomes of students of SMPN 2 Montasik .. This study used an experimental method with quantitative approach. The subjects were students of class IX1 and IX2 SMP 2 Montasik. The research sample was obtained from the class IX1 and IX2 with the number of 36 students. Data collection techniques in the form of tests carried out objectively against aspects that will be observed in the form of data. Data collection tools in the form of matter. The performance indicators is expected that students can increase learning achievement using the skills-based lab. The results showed that the average value grade students experiment = 75.05 and the value control class = 66. Thus seen that the method practical skills-based process is better than the usual practical method
Persepsi Mahasiswa Program Studi Pendidikan Fisika Fkip Unsyiah Terhadap Tindakan Plagiat Dalam Penulisan Skripsi
The purpose of this study was to determine students' perceptions of Unsyiah FKIP physical education courses against plagiarism in the thesis. The study population included 30 students who were menyusuk thesis. In this study, use data collection tool was a questionnaire. The data collection is done by giving questionnaires to the population, this research data processing using a percentage formula p = f / n x100%. These results indicate a physical education students did not agree with plagiarism, and student plagiarism mesih perform a variety of reasons
Efektivitas Ekstrak Biji Jintan Hitam (Nigella Sativa Linn.) Terhadap Infeksi Bakteri Streptococcus Agalactiae Pada Ikan Nila (Oreochromis Niloticus Linn.)
Black Cumin Seeds (Nigella sativa L.), commonly known as black seed, have been used in traditional medicine.Streptococcus agalactiae is a Gram-positive bacteria that causes the disease Streptococcosis in nile tilapia(Oreochromis niloticus L.). This study aims to find the bioactivity of black cumin seeds (N. sativa L.) againstbacterial pathogens in nile tilapia (O. niloticus L.). The research activities include preparation of samples blackcumin seeds (N. sativa L.), extraction with kinetic maceration method using solvents from different polarity (nhexane,ethanol and methanol), determination of antibacterial activity and minimum inhibition concentration(MIC) by agar diffusion method. The results of antibacterial activity against S. agalactiae of pathogenic bacteriashowed that the highest activity was performed by semi-polar extract ethanol (inhibition zone diameter of 15.33mm), followed by extract polar methanol with inhibition zone diameter of 12.67 mm. Extract non-polar nhexanedid not show any activities against the bacterial test. Determination of the minimum inhibitoryconcentration (MIC) of ethanol extract against S. agalactiae showed a value of 250 ppm
Expertise and Trust-Aware Social Web Service Recommendation
With the increasing number of Web services, the personalized recommendation of Web services has become more and more important. Fortunately, the social network popularity nowadays brings a good alternative for social recommendation to avoid the data sparsity problem that is not treated very well in the collaborative filtering approach. Since the social network provides a big data about the users, the trust concept has become necessary to filter this abundance and to foster the successful interactions between the users. In this paper, we firstly propose a trusted friend detection mechanism in a social network. The dynamic of the users’ interactions over time and the similarity of their interests have been considered. Secondly, we propose a Web service social recommendation mechanism which considers the expertise of the trusted friends according to their past invocation histories and the active user’s query. The experiments of each mechanism produced satisfactory results
Hubungan Derajat Klinis dengan Kadar Feritin Penyandang Thalassemia Β di RSUD Arifin Achmad
Thalassemia is a genetic disorder which there is interference with the synthesis of hemoglobin that causes a decreased of synthesis of α or β chain, If the abnormalities are β chain called β thalassemia. People with thalassemia need transfusion of red blood in rest of their life to maintain sufficient hemoglobin level, but the result in increased level of iron overload in body which can cause complication. This study aims to see the description and the correlation between clinical severity with ferritin level of β thalassemia at Arifin Achmad Hospital in Riau province. The method used is analytic with cross sectional approach. Disease severity assessed by Thailand score whereas ferritin level through laboratory test. Of 59 people with thalassemia there are as many as 49 people (83.1%) with moderate disease severity and 10 people (16.9%) with severe disease severity, whereas ferritin levels 2500 ng/ml as many as 39 people (66.1%). After analysis, there is no correlation between disease severity with ferritin level (p>0.05). The conclusion of this study, the highest data are thalassemia with moderate disease severity and ferritin level >2500 ng/ml, also there is no correlation between disease severity with ferritin level
Early changes in rpS6 phosphorylation and BH3 profiling predict response to chemotherapy in AML cells
Blasts from different patients with acute myeloid leukemia (AML) vary in the agent(s) to which they are most responsive. With a myriad of novel agents to evaluate, there is a lack of predictive biomarkers to precisely assign targeted therapies to individual patients. Primary AML cells often survive poorly in vitro, thus confounding conventional cytotoxicity assays. The purpose of this work was to assess the potential of two same-day functional predictive assays in AML cell lines to predict long-term response to chemotherapy. (i) Ribosomal protein S6 (rpS6) is a downstream substrate of PI3K/akt/mTOR/ kinase and MAPK kinase pathways and its dephosphorylation is also triggered by DNA double strand breaks. Phospho-rpS6 is reliably measurable by flow cytometry and thus has the potential to function as a biomarker of responsiveness to several therapeutic agents. (ii) A cell’s propensity for apoptosis can be interrogated via a functional assay termed “Dynamic BH3 Profiling” in which mitochondrial outer membrane permeabilization in drug-treated cells can be driven by pro-apoptotic BH3 domain peptides such as PUMA-BH3. The extent to which a particular cell is primed for apoptosis by the drug can be determined by measuring the amount of cytochrome C released on addition of BH3 peptide. We demonstrate that phospho-rpS6 expression and PUMA-BH3 peptide-induced cytochrome C release after 4 hours both predict long term chemoresponsiveness to tyrosine kinase inhibitors and DNA double strand break inducers in AML cell lines. We also describe changes in expression levels of the prosurvival BCL-2 family member Mcl-1 and the pro-apoptotic protein BIM after short term drug culture
Međudjelovanje atmosfere s morem u Jadranu: simulacije bure i juga
Two simulations of the response of Adriatic Sea to severe wind performed by an atmosphere-ocean coupled model and the comparisons with observed data and modelled fields published in literature are presented. The model RAMS-DieCAST was applied to simulate the variations of sea currents and temperature profiles, from surface to bottom, induced by two episodes of intense wind over the Adriatic sea: a Bora wind event that occurred in January 1995 and a Sirocco wind event in November 2002. The results of the simulations are compared with observed data at the sea surface. In the Bora episode, the computed surface temperatures are compared with satellite SSTs and in situ observed temperatures; in the Sirocco event the simulated surface currents and temperatures are compared with experimental data collected by surface drifters released in different regions of the Adriatic Sea during the same Sirocco event. In both episodes the simulated temperature trends agree with the observed values and during the Sirocco episode the current fields are in quite good agreement with the drifter data. The modelled sea temperature and velocity fields show also a good concordance with other simulation results in literature.Dvije simulacije jakog vjetra nad Jadranom simuliraju se združenim atmosfersko-oceanografskim modelom te se analiziraju i uspoređuju s mjerenjima i drugim objavljenim modeliranim poljima. U tu svrhu se koristi model RAMS-DieCAST za simulaciju promjena morskih struja i temperaturnih profila po vertikali, uzrokovanih dvjema epizodama intenzivnog vjetra nad Jadranom: burom u siječnju 1995. godine i jugom u studenom 2002. godine. Rezultati simulacija se uspoređuju s opažanjima na morskoj površini. Tijekom bure, modelirana površinska temperatura uspoređuje se s površinskom temperaturom mora dobivene satelitskim mjerenjima i mjerenjima temperature u određenim točkama prostora. Tijekom juga, simulirane površinske struje i temperature se uspoređuju s eksperimentalnim mjerenjima dobivenih na temelju površinskih driftera koji su pušteni u različitim dijelovima Jadrana za istu epizodu. U obje epizode trendovi simulirane temperature dobro se podudaraju s opažanjima. Također se tijekom juga, površinske struje dobro podudaraju s mjerenjima driftera. Modelirana temperatura mora kao i vektorsko polje brzina pokazuju dobro slaganje s rezultatima sličnih simulacija u literaturi
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