Lichen planus pigmentosus inversus: 3 cases

Lichen planus pigmentosus-inversus is a rare variant of lichen planus pigmentosus. The eruption of lichen planus pigmentosus-inversus occurs mainly in the flexural regions and presents with brownish macules and patches. Here we describe three cases of woman who presented with hyperpigmented lesions at the different body folds. Physical examination revealed multiple brownish macules and patches on the intertriginous area without pruritis, and histologic findings showed a regressive pattern of lichen planus. These clinical and histological findings were consistent with a diagnosis of lichen planus pigmentosus-inversus

Atypical presentation of a pediatric Pyoderma gangrenosum in an immunocompetent child: Case report

Pyoderma gangrenosum is relatively rare in the pediatric population with only 4% cases, the most common presentation in children is in the form of disseminated ulcerative lesions. The pathophysiology of PG is still poorly understood. Its diagnosis is often delayed, with an average of 2 months; This is explained by the low prevalence of the disease in children and the fact that it is misdiagnosed on the one hand and by confusion with an ecthymagangrenosum. The PG is in fact a diagnosis of exclusion in histology; non-specific aseptic neutrophil infiltration, once the diagnosis of pediatric PG has been confirmed, the search for an underlying etiology should be undertaken. In our case, the balance of immune deficiency was normal

Evolution spectaculaire d’un pemphigus végétant réfractaire aux thérapies conventionnelles sous Rituximab: à propos d’un cas

Le pemphigus végétant est une variété rare de pemphigus. Il n'y représente que 2%. Plusieurs traitements sont de mise pour traiter cette entité, on retrouve les corticostéroïdes topiques et/ou oraux en 1ère intension, les immunosuppresseurs tels que l'Azathioprine, la Cyclosporine, le Méthotrexate, le Cyclophosphamide et le Mycophénolate mofétil pour remédier au effet secondaires des stéroides. Certains cas restent réfractaires à tous ces traitements, l'utilisation du Rituximab a fait révolutionner la prise en charge du pemphigus, en particulier sa forme végétante. Nous rapportons le cas d'une patiente de 42ans, admise pour prise en charge d'un pemphigus végétant confirmé histologiquement et mise initialement sous corticothérapie en association avec immunosuppresseur sans amélioration, puis fut mise sous Rituximab avec une évolution spectaculaire

Kaposi’s sarcoma complicating long-term corticotherapy for rheumatoid arthritis

Kaposi’s sarcoma (KS) is a lymphoangioproliferative neoplasm induced by human herpes virus 8 (HHV-8). KS caused by iatrogenic immunosuppression is rare. Iatrogenic KS can present a therapeutic dilemma, as decreasing the level of immunosuppression may not be possible or may come at the high cost of organ rejection, such as in the case of organ transplant recipients or organ damage in the case of patients with autoimmune disorders. We report a new case of Kaposi’s sarcoma induced by corticosteroids

Sclérodermie localisée: à propos de 24 cas

La morphée ou sclérodermie localisée est définie par un état scléreux de la peau pouvant s’étendre aux tissus sous-cutanés mais sans phénomène de Raynaud ni atteinte viscérale. Certaines formes cliniques peuvent avoir un retentissement fonctionnel et esthétique, d’où l’intérêt d’une prise en charge précoce au stade inflammatoire. Nous décrivons les caractéristiques épidémio-cliniques, thérapeutiques et évolutives des différentes formes de morphée à travers une série de 24 cas

A painless glomus tumor: a case report

Abstract Background Glomus tumor is a benign and vascular hamartoma that originates from the neuromyoarterial cells of the normal glomus apparatus in the reticular dermis. The etiology of glomus tumors is unknown. It usually presents as a small, slightly raised, bluish or pinkish-red, painful nodule of the fingertips and the pulp. we report an atypical case of a patient of painless glomus tumor. Case presentation Our patient, a 60-year-old Moroccan man, had a 2.5 cm purplish painless soft tumor, covered with melliciric and hemorrhagic crusts, involving the first phalanx of his right index finger. This tumor was compressing his nail plate. No bony lesions were identified by radiographic studies, but magnetic resonance imaging was suggestive of glomus tumor. Surgical excision was performed with directed healing. Conclusions The diagnosis of a glomus tumor is an eventuality even in the absence of pain