The Ellis Archives-1972 to 1981: An Early View from the Parkdale Trenches

The author was intimately involved with PCLS from 1972 to 1981. Significant extracts from a recently uncovered, personal horde of archival materials--framed by the author\u27s description and explication of the materials\u27 original context--provide old perspectives on a wide range of surprisingly current issues--perspectives which the author believes readers will find still useful. The subject matter includes: the private bar\u27s role in the ultimate success of PCLS and the clinic system; legal aid services; the bar\u27s role in the legal aid system; the need for customized legal services in low-income communities; the role and operation of community based legal clinics; a closely considered analysis of a law school\u27s fundamental goals; and, finally, clinical education. The archival materials also provide unique windows on various facets of the PCLS program during its first decade

Field Evaluation of Herbicides on Rice 2003

Herbicide evaluation studies on rice were conducted in 2003 at the Rice Research and Extension Center near Stuttgart, Ark., in an effort to evaluate new herbicides, herbicide mixtures, and their application timings for weed control efficacy and crop tolerance. Results of these studies, in part, provide useful information to producers, fellow researchers, and the crop protection industry for the potential use of new herbicide programs for successful rice production in Arkansas

Field Evaluation of Herbicides on Vegetables, Small Fruit, and Ornamental Crops 2003

Herbicide evaluation studies on vegetables, small fruit, and ornamental crops were conducted in 2003 at the Arkansas Agricultural Experiment Station in Fayetteville, Ark., and the Vegetable Substation near Kibler, Ark., in an effort to evaluate new herbicides, herbicide mixtures, and their application timings for weed control efficacy and crop tolerance. Results of these studies, in part, provide useful information to producers, fellow researchers, the Crop Protection Industry, and the IR-4 Minor Crop Pest Management Program in the development of potential new herbicide uses in vegetable, fruit, and ornamental production

Economic and Financial Methodology for South Texas Irrigation Projects – RGIDECON©

(originally published October 2002

Criticality benchmark calculations using PARTISN: Comparisons using MENDF5 and MENDF6 nuclear data libraries.

A project was undertaken to assess the MENDF5 and MENDF6 nuclear data libraries through the analysis of 86 critical assembly benchmarks using the LANL discrete ordinates transport code PARTISN. As an initial analysis of the effects of some limitations in the MENDF libraries, this current work assesses differences in k,,a calculations between the PARTISN cases (with MENDF5 and MENDF6 nuclear data libraries) and MCNP cases, and compares these results to the experimental data

Structural basis for the RING catalyzed synthesis of K63 linked ubiquitin chains

This work was supported by grants from Cancer Research UK (C434/A13067), the Wellcome Trust (098391/Z/12/Z) and Biotechnology and Biological Sciences Research Council (BB/J016004/1).The RING E3 ligase catalysed formation of lysine 63 linked ubiquitin chains by the Ube2V2–Ubc13 E2 complex is required for many important biological processes. Here we report the structure of the RING domain dimer of rat RNF4 in complex with a human Ubc13~Ub conjugate and Ube2V2. The structure has captured Ube2V2 bound to the acceptor (priming) ubiquitin with Lys63 in a position that could lead to attack on the linkage between the donor (second) ubiquitin and Ubc13 that is held in the active “folded back” conformation by the RING domain of RNF4. The interfaces identified in the structure were verified by in vitro ubiquitination assays of site directed mutants. This represents the first view of the synthesis of Lys63 linked ubiquitin chains in which both substrate ubiquitin and ubiquitin-loaded E2 are juxtaposed to allow E3 ligase mediated catalysis.PostprintPeer reviewe

National Telemedicine Initiatives: Essential to Healthcare Reform

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/78116/1/tmj.2009.9960.pd

The Las Campanas Infrared Survey. IV. The Photometric Redshift Survey and the Rest-frame R-band Galaxy Luminosity Function at 0.5 <= z <= 1.5

(Abridged) We present rest-frame R-band galaxy luminosity function measurements for three different redshift ranges: 0.5<=z<=0.75, 0.75<=z<=1.0, and 1.0<=z<=1.5. Our measurements are based on photometric redshifts for ~3000 H-band selected galaxies with apparent magnitudes 17<=H<=20 from the Las Campanas Infrared Survey. We show that our photometric redshifts are accurate with an RMS dispersion between the photometric and spectroscopic redshifts of \sigma_z/(1+z)~0.08. Using galaxies identified in the Hubble Deep Field South and Chandra Deep Field South regions, we find, respectively, that (7.3\pm 0.2) % and (16.7\pm 0.4)% of the H=1. We first demonstrate that the systematic uncertainty inherent in the luminosity function measurements due to uncertainties in photometric redshifts is non-negligible and therefore must be accounted for. We then develop a technique to correct for this systematic error by incorporating the redshift error functions of individual galaxies in the luminosity function analysis. The redshift error functions account for the non-gaussian characteristics of photometric redshift uncertainties. They are the products of a convolution between the corresponding redshift likelihood functions of individual galaxies and a Gaussian distribution function that characterizes template-mismatch variance. We demonstrate, based on a Monte Carlo simulation, that we are able to completely recover the bright end of the intrinsic galaxy luminosity function using this technique. Finally, we calculate the luminosity function separately for the total H-band selected sample and for a sub-sample of early-type galaxies that have a best-fit spectral type of E/S0 or Sab from the photometric redshift analysis.Comment: 42 pages and 12 figures; Accepted for publication in the Astrophysical Journa

Polymer-based paclitaxel-eluting stents reduce in-stent neointimal tissue proliferation A serial volumetric intravascular ultrasound analysis from the TAXUS-IV trial

ObjectivesThe aim of this study was to use serial volumetric intravascular ultrasound (IVUS) to evaluate the effects of polymer-based, paclitaxel-eluting stents on in-stent neointima formation and late incomplete stent apposition.BackgroundThe TAXUS-IV trial demonstrated that the slow-release, polymer-based, paclitaxel-eluting stent reduces angiographic restenosis and the need for repeat revascularization procedures. Serial IVUS studies reveal details of the pattern of vascular responses provoked by stent implantation that provide insight into device safety and efficacy.MethodsIn the TAXUS-IV trial, patients were randomized to the slow-release, polymer-based, paclitaxel-eluting TAXUS stent or a bare-metal EXPRESS stent (Boston Scientific Corp., Natick, Massachusetts). As part of a formal substudy, complete volumetric IVUS data were available in 170 patients, including 88 TAXUS patients and 82 controls, at implantation and at nine-month follow-up.ResultsNo baseline differences were present in the clinical characteristics or IVUS parameters between the control and TAXUS groups. At nine-month follow-up, IVUS lumen volumes were larger in the TAXUS group (123 ± 43 mm3vs. 104 ± 44 mm3, p = 0.005), due to a reduction in neointimal volume (18 ± 18 mm3vs. 41 ± 23 mm3, p < 0.001). Millimeter-by-millimeter analysis within the stent demonstrated uniform suppression of neointimal growth along the entire stent length. Late lumen loss was similar at the proximal edge of the stent between the two groups, and reduced with the TAXUS stent at the distal edge (p = 0.004). Incomplete stent apposition at nine months was observed in only 3.0% of control and 4.0% of TAXUS stents (p = 0.12).ConclusionsPolymer-based, paclitaxel-eluting TAXUS stents are effective in inhibiting neointimal tissue proliferation, and do not result in late incomplete stent apposition

Financing Direct Democracy: Revisiting the Research on Campaign Spending and Citizen Initiatives

The conventional view in the direct democracy literature is that spending against a measure is more effective than spending in favor of a measure, but the empirical results underlying this conclusion have been questioned by recent research. We argue that the conventional finding is driven by the endogenous nature of campaign spending: initiative proponents spend more when their ballot measure is likely to fail. We address this endogeneity by using an instrumental variables approach to analyze a comprehensive dataset of ballot propositions in California from 1976 to 2004. We find that both support and opposition spending on citizen initiatives have strong, statistically significant, and countervailing effects. We confirm this finding by looking at time series data from early polling on a subset of these measures. Both analyses show that spending in favor of citizen initiatives substantially increases their chances of passage, just as opposition spending decreases this likelihood