The atmospheric effects of stratospheric aircraft. Report of the 1992 Models and Measurements Workshop. Volume 1: Workshop objectives and summary

This Workshop on Stratospheric Models and Measurements (M&M) marks a significant expansion in the history of model intercomparisons. It provides a foundation for establishing the credibility of stratospheric models used in environmental assessments of chlorofluorocarbons, aircraft emissions, and climate-chemistry interactions. The core of the M&M comparisons involves the selection of observations of the current stratosphere (i.e., within the last 15 years): these data are believed to be accurate and representative of certain aspects of stratospheric chemistry and dynamics that the models should be able to simulate

The atmospheric effects of stratospheric aircraft. Report of the 1992 Models and Measurements Workshop. Volume 3: Special diagnostic studies

This Workshop on Stratospheric Models and Measurements (M&M) marks a significant expansion in the history of model intercomparisons. It provides a foundation for establishing the credibility of stratospheric models used in environmental assessments of chlorofluorocarbons, aircraft emissions, and climate-chemistry interactions. The core of the M&M comparisons involves the selection of observations of the current stratosphere (i.e., within the last 15 years): these data are believed to be accurate and representative of certain aspects of stratospheric chemistry and dynamics that the models should be able to simulate

Dynamic reorganization of the middle fusiform gyrus: long-term bird expertise predicts decreased face selectivity

What is the functional relationship between face-selective and expertise-predicated object-selective regions in the human middle fusiform gyrus? In two separate fMRI experiments, superior behaviorally-measured bird expertise predicts both higher middle fusiform gyrus selectivity for birds and, concomitantly, lower selectivity for faces. This finding suggests a long-term dynamic reorganization of the neural mechanisms underlying the visual recognition of faces and non-face

Current activities in standardization of high-temperature, low-cycle-fatigue testing techniques in the United States

The American Society for Testing and Materials (ASTM) standard E606-80 is the most often used recommended testing practice for low-cycle-fatigue (LCF) testing in the United States. The standard was first adopted in 1977 for LCF testing at room temperature and was modified in 1980 to include high-temperature testing practices. Current activity within ASTM is aimed at extending the E606-80 recommended practices to LCF under thermomechanical conditions, LCF in high-pressure hydrogen, and LCF in metal-matrix composite materials. Interlaboratory testing programs conducted to generate a technical base for modifying E606-80 for the aforementioned LCF test types are discussed

Riboregulation of Bacterial Transposons

Bacterial transposons typically exist in a mutually beneficial relationship with the host cell. Limited transposition can benefit the host while also ensuring the survival of the element. An important component of this relationship is that transposition must be tightly regulated. In this thesis I explore ways that the host and transposon each control transposition in E. coli and provide evidence that a transposon can also control host gene expression in S. enterica Typhimurium. Post-transcriptional regulation with small non-coding RNAs (sRNA) has emerged as a key way that bacteria respond to stress and regulate many cellular processes. The RNA-binding protein Hfq is the nexus of sRNA regulatory networks and acts by promoting base-pairing interactions between sRNAs and their target mRNAs. Previous work found that Hfq is a potent negative regulator of IS10 transposition in E. coli and suggested that Hfq inhibited transposase translation using an IS10-encoded sRNA (RNA-OUT) as well as an undefined mechanism that was independent of RNA-OUT. I show that Hfq promotes base-pairing between RNA-OUT and IS10 transposase mRNA (RNA-IN) by melting the secondary structure of both RNAs to expose residues involved in intermolecular base-pairing. I also investigated how Hfq can repress translation of RNA-IN in the absence of RNA-OUT and demonstrate that Hfq-binding to an mRNA can directly repress translation in the absence of any sRNA. The data suggested Hfq may regulate other transposons and I show that the unrelated IS200 element is also subject to Hfq regulation. In contrast to the IS10 system, Hfq represses IS200 transposase (tnpA) translation completely independent of the IS200-encoded sRNA (art200). Translation initiation on tnpA is inhibited \u3e350-fold by the cooperation of Hfq, art200, and an RNA structural element in the tnpA 5’UTR illustrating how host- and transposon-encoded factors can coordinate to repress transposition. Lastly, I demonstrate that tnpA is processed to produce an sRNA that alters transcript abundance \u3e2-fold for 73 S. enterica Typhimurium genes, which provides a new twist on our understanding of host-transposon interactions. Taken together, this work suggests that RNA transactions play an important role in governing host-transposon relationships in bacteria

Thermomechanical testing techniques for high-temparature composites: TMF behavior of SiC(SCS-6)/Ti-15-3

Thermomechanical testing techniques recently developed for monolithic structural alloys were successfully extended to continuous fiber reinforced composite materials in plate form. The success of this adaptation was verified on a model metal matrix composite (MMC) material, namely SiC(SCS-6)/Ti-15V-3Cr-3Al-3Sn. Effects of heating system type and specimen preparation are also addressed. Cyclic lives determined under full thermo-mechanical conditions were shown to be significantly reduced from those obtained under comparable isothermal and in-phase bi-thermal conditions. Fractography and metallography from specimens subjected to isothermal, out-of-phase and in-phase conditions reveal distinct differences in damage-failure modes. Isothermal metallography revealed extensive matrix cracking associated with fiber damage throughout the entire cross-section of the specimen. Out-of-phase metallography revealed extensive matrix damage associated with minimal (if any) fiber cracking. However, the damage was located exclusively at surface and near-surface locations. In-phase conditions produced extensive fiber cracking throughout the entire cross-section, associated with minimal (if any) matrix damage

Potentials between D-Branes in a Supersymmetric Model of Space-Time Foam

We study a supersymmetric model of space-time foam with two stacks each of eight D8-branes with equal string tensions, separated by a single bulk dimension containing D0-brane particles that represent quantum fluctuations. The ground-state configuration with static D-branes has zero vacuum energy, but, when they move, the interactions among the D-branes and D-particles due to the exchanges of strings result in a non-trivial, positive vacuum energy. We calculate its explicit form in the limits of small velocities and large or small separations between the D-branes and/or the D-particles. This non-trivial vacuum energy appears as a central charge deficit in the non-critical stringy $\sigma$ model describing perturbative string excitations on a moving D-brane. These calculations enable us to characterise the ground state of the D-brane/D-particle system, and provide a framework for discussing brany inflation and the possibility of residual Dark Energy in the present-day Universe.Comment: 26 pages Latex, four eps figures incorporated, minor typos corrected, no effects on conclusion

Exocentric direction judgements in computer-generated displays and actual scenes

One of the most remarkable perceptual properties of common experience is that the perceived shapes of known objects are constant despite movements about them which transform their projections on the retina. This perceptual ability is one aspect of shape constancy (Thouless, 1931; Metzger, 1953; Borresen and Lichte, 1962). It requires that the viewer be able to sense and discount his or her relative position and orientation with respect to a viewed object. This discounting of relative position may be derived directly from the ranging information provided from stereopsis, from motion parallax, from vestibularly sensed rotation and translation, or from corollary information associated with voluntary movement. It is argued that: (1) errors in exocentric judgements of the azimuth of a target generated on an electronic perspective display are not viewpoint-independent, but are influenced by the specific geometry of their perspective projection; (2) elimination of binocular conflict by replacing electronic displays with actual scenes eliminates a previously reported equidistance tendency in azimuth error, but the viewpoint dependence remains; (3) the pattern of exocentrically judged azimuth error in real scenes viewed with a viewing direction depressed 22 deg and rotated + or - 22 deg with respect to a reference direction could not be explained by overestimation of the depression angle, i.e., a slant overestimation