Insects of Western North America. 2. The cicadas of Colorado (Homoptera: Cicadidae, Tibicinidae)

May 15, 2002

New X-ray Clusters in the EMSS II: Optical Properties

We present optical images for 9 new clusters of galaxies we have found in a reanalysis of the Einstein IPC images comprising the Extended Medium Sensitivity Survey (EMSS). Based on the presence of a red sequence of galaxies in a color-magnitude (CM) diagram, a redshift is estimated for each cluster. Galaxy overdensities (cluster richnesses) are measured in each field using the B_gc statistic which allows their plausible identification with the X-ray emission. The nature of our X-ray detection algorithm suggests that most of these clusters have low X-ray surface brightness (LSB) compared to the previously known EMSS clusters. We compare the optical and X-ray observations of these clusters with the well-studied Canadian Network for Observational Cosmology (CNOC) subsample of the EMSS, and conclude that the new clusters exhibit a similar range of optical richnesses, X-ray luminosities, and, somewhat surprisingly, galaxy populations as the predominantly rich, relaxed EMSS/CNOC clusters.Comment: Accepted to ApJ, 17 pages, 14 figures, uses emulateapj5.st

Sensitive species and natural communities known to occur on the Picket Wire Canyonlands, Comanche National Grassland, Colorado

November 15, 1995.Christopher A. Pague ... [et al.]

The X-ray Size-Temperature Relation for Intermediate Redshift Galaxy Clusters

We present the first measurements of the X-ray size-temperature (ST) relation in intermediate redshift (z~0.30) galaxy clusters. We interpret the local ST relation (z~0.06) in terms of underlying scaling relations in the cluster dark matter properties, and then we use standard models for the redshift evolution of those dark matter properties to show that the ST relation does not evolve with redshift. We then use ROSAT HRI observations of 11 clusters to examine the intermediate redshift ST relation; for currently favored cosmological parameters, the intermediate redshift ST relation is consistent with that of local clusters. Finally, we use the ST relation and our evolution model to measure angular diameter distances; with these 11 distances we evaluate constraints on Omega_M and Omega_L which are consistent with those derived from studies of Type Ia supernovae. The data rule out a model with Omega_M=1 and Omega_L=0 with 2.5 sigma confidence. When limited to models where Omega_M+Omega_L=1, these data are inconsistent with Omega_M=1 with 3 sigma confidence.Comment: ApJ: submitted April 7, accepted June 28, to appear Dec 1 (vol 544

Natural heritage inventory of the town of Vail: final report

Prepared for: the town of Vail.March 29, 1994

New X-ray Clusters in the EMSS I: Modifications to the XLF

The complete ensemble of Einstein Imaging Proportional Counter (IPC) X-ray images has been re-processed and re-analyzed using a multi-aperture source detection algorithm. A catalog of 772 new source candidates detected within the central regions of the 1435 IPC fields comprising the Extended Medium Sensitivity Survey (EMSS) has been compiled. By comparison, 478 EMSS sources fall within the same area of sky. A randomly-selected subsample of 133 fields was first examined. We found that most of these sources are either the summation of two or more lower count rate point sources that fall within the larger detection apertures or are single point sources, while \leq 2.3% of the full catalog of sources are extrapolated to be actual distant (z > 0.14) clusters whose extended X-ray structure kept them from being detected in the EMSS despite having sufficient total flux. We then constructed other subsamples specifically selected to contain those X-ray sources most likely to be clusters. Both a database search and an optical imaging campaign have found several new distant clusters, setting a firm lower limit on the number of new clusters in the entire catalog. We estimate that the original EMSS cluster sample is 72-83% complete. We update the Henry et al. 1992 EMSS distant cluster sample with more recent information, and use the redshifts and X-ray luminosities for these new EMSS clusters to compute a revised X-ray Luminosity Function (XLF). The addition of these new high-z, high-L_X clusters to the EMSS is sufficient to remove the requirement for ``negative'' evolution at high-L_X out to z~0.5. We conclude that the EMSS has systematically missed clusters of low surface brightness.Comment: Accepted to ApJ, 32 pages, 8 figures, uses emulateapj5.sty, for associated data table see http://casa.colorado.edu/~lewisad/research/nemsscatalog.htm

Neoadjuvant anti-PD-1 immunotherapy promotes a survival benefit with intratumoral and systemic immune responses in recurrent glioblastoma.

Glioblastoma is the most common primary malignant brain tumor in adults and is associated with poor survival. The Ivy Foundation Early Phase Clinical Trials Consortium conducted a randomized, multi-institution clinical trial to evaluate immune responses and survival following neoadjuvant and/or adjuvant therapy with pembrolizumab in 35 patients with recurrent, surgically resectable glioblastoma. Patients who were randomized to receive neoadjuvant pembrolizumab, with continued adjuvant therapy following surgery, had significantly extended overall survival compared to patients that were randomized to receive adjuvant, post-surgical programmed cell death protein 1 (PD-1) blockade alone. Neoadjuvant PD-1 blockade was associated with upregulation of T cell- and interferon-γ-related gene expression, but downregulation of cell-cycle-related gene expression within the tumor, which was not seen in patients that received adjuvant therapy alone. Focal induction of programmed death-ligand 1 in the tumor microenvironment, enhanced clonal expansion of T cells, decreased PD-1 expression on peripheral blood T cells and a decreasing monocytic population was observed more frequently in the neoadjuvant group than in patients treated only in the adjuvant setting. These findings suggest that the neoadjuvant administration of PD-1 blockade enhances both the local and systemic antitumor immune response and may represent a more efficacious approach to the treatment of this uniformly lethal brain tumor

Reduced dielectric screening and enhanced energy transfer in single and few-layer MoS2

We report highly efficient non-radiative energy transfer from cadmium selenide (CdSe) quantum dots to monolayer and few-layer molybdenum disulfide (MoS2). The quenching of the donor quantum dot photoluminescence increases as the MoS2 flake thickness decreases, with the highest efficiency (>95%) observed for monolayer MoS2. This counterintuitive result arises from reduced dielectric screening in thin layer semiconductors having unusually large permittivity and a strong in-plane transition dipole moment, as found in MoS2. Excitonic energy transfer between a 0D emitter and a 2D absorber is fundamentally interesting and enables a wide range of applications including broadband optical down-conversion, optical detection, photovoltaic sensitization, and color shifting in light-emitting devices.Comment: 14 pages, 4 figure