Flowchart heart failure.

<p>1a. The first question is <i>“Symptoms¹?”</i>, “number 1″ refers to block 1 under the step diagram, in this block symptoms of heart failure are shown, so the user knows which symptoms could occur; When the answer is “NO”. 1b. Is the <i>“EF<40%-20% or the FS<15%”</i> YES grade 3 heart failure. NO grade ≤2 heart failure. When the answer is “YES” Go to question “Responsive to intervention²?” 2. Question <i>“Responsive to intervention²?”</i>, block 2 in which common interventions for heart failure are shown; When the answer is “NO” grade 4 heart failure. When the answer is “YES” grade 3 heart failure. When it is “UNKNOWN” go to question “ <i>Device³, life threatening consequences⁴ or heart transplant?”</i>. 3. Question “ Device³, life threatening consequences⁴ or heart transplant?”, block 3 under the step diagram, in this block devices used as treatment for heart failure are shown. In block 4 the life threatening consequences associated with heart failure are stated; When the answer is “NO” grade 3 heart failure. When the answer is “YES” grade 4 heart failure. Ref. <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0100432#pone.0100432-Dickstein1" target="_blank">[10]</a>, <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0100432#pone.0100432-McMurray1" target="_blank">[11]</a>. ICD-10 = International classification of disease version 10. EF = ejection fraction. SF = shortening fraction. CRT-P or D = cardiac resynchronisation therapy pacemaker or defibrillator. ICD = implantable cardioverse defibrillator. LVAD = left ventricular assistance device.</p

Definitions of cardiac events (using CTCAEv3.0 and CTCAEv4.0).

<p>Definitions of cardiac events (using CTCAEv3.0 and CTCAEv4.0).</p

Result second consistency assessment (non-physician (NP) vs non-physician (extensive training) (NPE)).

<p>Result second consistency assessment (non-physician (NP) vs non-physician (extensive training) (NPE)).</p