Clinical and demographic parameters of all the subjects included in the study.

<p>Clinical and demographic parameters of all the subjects included in the study.</p

White matter MRI parameters in MSON+ and MSON-.

<p>Results are reported as median (IQR). P-values were obtained from GEE model. GEE analysis was performed at eye-level. White Matter Lesion Volume: WMLV; percentage of WMLV: WMLV%; optic radiation WMLV: OR-WMLV; percentage of OR-WMLV: OR-WMLV%. Other abbreviations as in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0183957#pone.0183957.t001" target="_blank">Table 1</a>.</p

Correlations between RNFL and cortical thickness.

<p>Correlations between RNFL and cortical thickness.</p

Comparison of the RNFL’s sector values.

<p>Healthy Controls: HC-OCT; Not Optic Neuritis MS patients: MSON-; Optic Neuritis MS patients: MSON+; affected eye MSON+: aON+; not affected eye MS ON+: naON+.</p

Cortical thickness values in MSON-, HC-MRI and MSON+.

<p>Cortical thickness values in MSON-, HC-MRI and MSON+.</p