35 research outputs found
US Cosmic Visions: New Ideas in Dark Matter 2017: Community Report
This white paper summarizes the workshop "U.S. Cosmic Visions: New Ideas in
Dark Matter" held at University of Maryland on March 23-25, 2017.Comment: 102 pages + reference
Value destruction and value preservation
The chapter points out how carving out valuable business units from the the troubled company helps preserving value. This can be made either in a judicial procedure like a PAC (Preventive Arrangement with Creditors) or without any procedure. Operational details are explored through real life business cases. The risk of value destruction is high. In this respect we outline some issues related to judicial procedures, such as the economic burden of these very costly procedures, the loss of flexibility that they imply and the stuffy, conservative management style that is often involved
Book framework and early reasonings
The chapter explains the overall project underlying the book, pointing out many different issues related to rescuing troubled companies. The basic question is the following: is a corporate turnaround always worthwhile? The answer is “not always”, as the viability of any turnaround has to be assessed on the basis of a quantitative analysis of the viable alternatives of action. The reasons why book values in the financial reports of troubled companies may not be true and fair are outlined as well as the consequent reality gap
La struttura finanaziaria delle imprese
Le scelte di struttura finanziaria analizzate in diversi approcci forniti dalla dottrina richiedono di essere effettuate alla luce di variabili operative e di contesto che ne determinano poi l’efficacia. La relazione tra struttura finanziaria ed equity value è dunque pregnante
Corporate turnaround : the Italian perspective
No abstract availabl
Rem Sleep Without Atonia (RSWA) and neuropsychological function in REM sleep Behavior Disorder
Introduction
REM sleep Behavior Disorder (RBD) is a parasomnia characterized by the presence of REM Sleep Without Atonia (RSWA) resulting in abnormal and violent behaviors. Evidence from literature demonstrates that Isolated RBD (IRBD) is a prodromal phase of neurodegenerative diseases with high conversion rates in synucleinopathies. The aim of the study is to investigate the relationship between cognitive impairment and RSWA in IRBD patients.
Methods
35 IRBD patients and 18 healthy controls (HC) were recruited, underwent a complete polysomnography (PSG) as well as a comprehensive neuropsychological evaluation. Moreover, IRBD patients were divided into two groups based on the presence or absence of Mild Cognitive Impairment (MCI). The PSG were analyzed by a scorer, blind to subjects’ diagnosis, to quantify the RSWA of six different indices of muscle activity extracted by phasic and tonic events recorded in different time series (miniepochs of 2 or 3 seconds, or epochs of 30 seconds) and muscle combinations (flexor digitorum superficialis, mentalis and tibialis muscles).
Results
Comparative analyses showed that the percentages of RSWA were significantly higher in the IRBD group than HC. The best discriminative power was obtained by the combination of phasic and tonic events recorded in micro epochs of 3 seconds from the mentalis muscle and flexor digitorum superficialis (IRBD 0.787 ±0.195, HC 0.306±0.183, p<0.001; area under the curve=0.952). The correlation analyses between RSWA indices and neuropsychological measures in the IRBD group showed a significant negative correlation (rspearman=-0.374, p=0.029) between the scores at the Mini-Mental State Examination (MMSE) and the phasic events index recorded by the combination of mentalis and bilateral tibialis muscles in micro epochs of 2 seconds. Finally, comparative analyses between MCI and no-MCI with regard to RSWA indices did not demonstrate significant differences. However, MCI indices were systematically higher in comparison to no-MCI for each index taken into account.
Conclusion
These results suggest an association between RSWA and cognitive functioning that may provide an insight on the relationship between the loss of atonia during REM sleep and neurodegenerative processes