Semantic priming over unrelated trials: evidence for different effects in word and picture naming

Two naming experiments are reported that replicated previous findings of semantic interference as a result of naming related word or picture primes three trials before picture targets. We also examined whether semantic interference occurred when the materials were reversed and picture or word primes were named before word targets. The interest in semantic interference during word naming followed a suggestion made by Humphreys, Lloyd-Jones, and Fias (1995) that word naming, like picture naming, may be reliant on a semantic route to name retrieval when the two stimuli are mixed. In contrast to their findings, we found no evidence for semantic interference during target word naming; in fact, we found facilitation from related picture primes. No priming was found for the related word prime and word target condition. The data allow us to rule out the possibility that word naming is reliant on a semantic route when mixed with pictures in this priming paradigm and to conclude that there is no clear evidence of semantic activation during word naming. We also conclude, in line with other research, that word naming and picture naming involve different processes

Question asking and eye tracking during cognitive disequilibrium: comprehending illustrated texts on devices when the devices break down

The PREG model of question asking assumes that questions emerge when there is cognitive disequilibrium, as in the case of contradictions, obstacles, and anomalies. Participants read illustrated texts about everyday devices (e.g., a cylinder lock) and then were placed in cognitive disequilibrium through a breakdown scenario (e.g., the key turns but the bolt does not move). The participants asked questions when given the breakdown scenario, and an eyetracker recorded their fixations. As was predicted, deep comprehenders asked better questions and fixated on device components that explained the malfunction. The eye fixations were examined before, during, and after the participants\u27 questions in order to trace the occurrence and timing of convergence on faults, causal reasoning, and other cognitive processes

Postoperative continuous positive airway pressure to prevent pneumonia, re-intubation, and death after major abdominal surgery (PRISM): a multicentre, open-label, randomised, phase 3 trial

Background: Respiratory complications are an important cause of postoperative morbidity. We aimed to investigate whether continuous positive airway pressure (CPAP) administered immediately after major abdominal surgery could prevent postoperative morbidity. Methods: PRISM was an open-label, randomised, phase 3 trial done at 70 hospitals across six countries. Patients aged 50 years or older who were undergoing elective major open abdominal surgery were randomly assigned (1:1) to receive CPAP within 4 h of the end of surgery or usual postoperative care. Patients were randomly assigned using a computer-generated minimisation algorithm with inbuilt concealment. The primary outcome was a composite of pneumonia, endotracheal re-intubation, or death within 30 days after randomisation, assessed in the intention-to-treat population. Safety was assessed in all patients who received CPAP. The trial is registered with the ISRCTN registry, ISRCTN56012545. Findings: Between Feb 8, 2016, and Nov 11, 2019, 4806 patients were randomly assigned (2405 to the CPAP group and 2401 to the usual care group), of whom 4793 were included in the primary analysis (2396 in the CPAP group and 2397 in the usual care group). 195 (8\ub71%) of 2396 patients in the CPAP group and 197 (8\ub72%) of 2397 patients in the usual care group met the composite primary outcome (adjusted odds ratio 1\ub701 [95% CI 0\ub781-1\ub724]; p=0\ub795). 200 (8\ub79%) of 2241 patients in the CPAP group had adverse events. The most common adverse events were claustrophobia (78 [3\ub75%] of 2241 patients), oronasal dryness (43 [1\ub79%]), excessive air leak (36 [1\ub76%]), vomiting (26 [1\ub72%]), and pain (24 [1\ub71%]). There were two serious adverse events: one patient had significant hearing loss and one patient had obstruction of their venous catheter caused by a CPAP hood, which resulted in transient haemodynamic instability. Interpretation: In this large clinical effectiveness trial, CPAP did not reduce the incidence of pneumonia, endotracheal re-intubation, or death after major abdominal surgery. Although CPAP has an important role in the treatment of respiratory failure after surgery, routine use of prophylactic post-operative CPAP is not recommended