Characteristics of study participants.

1<p>There were significantly more males in the group with mild dysplasia and colorectal cancer compared to the group of healthy individuals (p<0.001, Chi squared test).</p>2<p>The age is significant higher among patients with CRC compared to the three other groups (Kruskal-Wallis and Dunn's Multiple Comparison test, p<0.001).</p>3<p>Normal endoscopy.</p

<i>NFKB1</i> mRNA levels in morphologicallynon-affected and affected tissues normalised to the <i>β-actin</i> mRNA level.

<p>NS = not significant.</p>a<p>P-value for the comparison to the expression levels in tissue from healthy individuals using Kruskal Wallis and Dunńs Multiple Comparison test.</p>b<p>P-value for the comparison of the expression levels in normal and affected tissue from the same individual using Paired Student’s t-test.</p

<i>ABCB1</i> mRNA levels in morphologically normal and affected tissues normalised to the <i>β-actin</i> mRNA level.

<p><i>*P-</i>value <0.05, **<i>P-</i>value <0.01, ***<i>P-</i>value <0.001.</p

<i>NFKB1</i> mRNA levels in morphologically normal and affected tissues normalised to the <i>β-actin</i> mRNA level.

<p>***<i>P-</i>value <0.001.</p

<i>ABCB1</i> mRNA levels in morphologically non-affected and affected tissues normalised to the <i>β-actin</i> mRNA level.

<p>NS = not significant.</p>a<p>p-value for the comparison to the expression levels in tissue from healthy individuals using Kruskal Wallis and Dunńs Multiple Comparison test.</p>b<p>p-value for the comparison of the expression levels in normal and affected tissue from the same individual using Paired Student’s t-test.</p

Relation between <i>ABCB1</i> C-rs3789243-T, C3435T and <i>NFKB1</i> -94ins/del polymorphisms and <i>ABCB1</i> mRNA level in morphologically normal and affected intestinal tissue from individuals with adenomas (left panel) and CRC (right panel).

<p>The number of individuals with each genotype is indicated in brackets above the column. <i>*P-</i>value <0.05.</p