Direct Estimates of the Genomic Contributions to Blood Pressure Heritability within a Population-Based Cohort (ARIC) - Fig 1

<p><b>(a)</b> Estimates of the variance explained by SNPs by chromosome (<i>h</i>^<i>2</i>_<i>c</i>) for SBP (red) and DBP (blue) by joint analysis of 8,901 EA individuals. The trait analyzed is first-visit and long-term average SBP and DBP respectively with analyses using genotyped and imputed SNPs, <b>(b)</b> Legend as in <b>(a)</b> but for 2,860 AA individuals.</p

Direct Estimates of the Genomic Contributions to Blood Pressure Heritability within a Population-Based Cohort (ARIC) - Fig 2

<p><b>(a)</b> Estimates of the variance explained for SBP (red) and DBP (blue) by functional annotation class (promoter, UTR, DHS, exon, intron, intergenic) by joint analysis using genotyped and imputed SNPs for first-visit SBP and DBP respectively in 8,901 EA individuals, <b>(b)</b> Legend as in <b>(a)</b> but for 2,860 AA individuals.</p

Proportion of the genetic variance explained as a function of minor allele frequency (MAF) class using 8,901 EA and 2,860 AA individuals.

<p>The traits analyzed are first-visit SBP and DBP respectively for genotyped and imputed SNPs. The heritability (h²), its standard error (se) and significance value (P) are shown.</p

Proportion of the genetic variance explained by chromosome (joint) and the whole genome (combined) using 8,901 EA and 2,860 AA individuals.

<p>The trait analyzed is first-visit SBP and DBP and long-term average (LTA) SBP and DBP respectively using genotyped and imputed SNPs. The heritability (h²), its standard error (se) and significance value (P) are shown.</p

Intervention dans le Podcast les Arts du FLE pour faire le point sur la perspective actionnelle en classe de langues

Ce podcast est disponible en ligne, à l'adresse suivante :https://agi.to/podcast/arts-du-fle-08-actionne-ton-approche/Ce numéro 8 des Arts du FLE (émission spécialisée en FLE) propose un dossier spécial approches pédagogiques et perspective actionnelle. J'en suis l'invitée et j'y réponds de manière détaillée pendant près d'une heure aux questions de l'animateur et créateur de ce Podcast, Sébastien Durietz (en poste actuellement à l'ONU, à New-York)

Additional file 6: Figures S1–S4. of DNA methylation signatures of chronic low-grade inflammation are associated with complex diseases

(PDF 1036 kb

Additional file 10: Table S9. of DNA methylation signatures of chronic low-grade inflammation are associated with complex diseases

Significant associations between DNA methylation and corresponding nearby genetic variants and between the genetic variant and CRP in the largest published GWAS of CRP (n = 66,185). (XLSX 12 kb

Additional file 9: Table S8. of DNA methylation signatures of chronic low-grade inflammation are associated with complex diseases

Significant methylation-expression results and corresponding expression-CRP results for the replicated CpGs. (XLSX 11 kb