Cardiometabolic risk factors in pediatric kidney transplant recipients

Objective: There is an increased risk of obesity and metabolic syndrome among kidney transplant recipients, which adversely affects cardiovascular and renal outcomes in these patients. The present study aims to investigate the prevalence of metabolic syndrome in pediatric kidney transplant recipients and the associations of metabolic syndrome with cardiovascular disease and graft function. Materials and Methods: This cross-sectional, single-center study included 52 kidney transplant recipients (27 males) transplanted before 18 years of age. All subjects underwent a comprehensive assessment that included anthropometric and blood pressure measurements and laboratory tests. Metabolic syndrome was defined based on the recent recommendations of the Pediatric Renal Nutrition Taskforce. Left ventricular hypertrophy was assessed as a risk factor for cardiovascular disease, and estimated glomerular filtration rate was assessed to determine graft function. Results: The median age of patients was 15.9 (13.8;18.4) years, and the median follow-up time was 35.5 (20.0;62;0) months after transplantation. Nineteen patients (36.5%) were obese or overweight, 43 (83%) had hypertension or controlled hypertension, 23 (44%) had dyslipidemia, and 9 (17%) had hyperglycemia. Ten patients (19.2%) were diagnosed with metabolic syndrome. Twenty-eight patients (54%) had left ventricular hypertrophy. The prevalence of left ventricular hypertrophy was higher in patients with metabolic syndrome than in those without metabolic syndrome (90% vs. 45%, P =.014), whereas estimated glomerular filtration rate did not differ between the 2 groups. Conclusion: Cardiometabolic risk factors are common in pediatric kidney transplant recipients. Approximately one-fifth of patients have metabolic syndrome, and left ventricular hypertrophy is much more common among patients with metabolic syndrome. However, there is no relationship between metabolic syndrome and graft dysfunction

Reviewing the reviewers: The first name publications of referees of the Journal of Turkish Association of Pediatric Surgeons in PUBMED Deǧerlendirenlerin deǧerlendirilmesi: Çocuk Cerrahisi Dergisi hakemlerinin Pubmed'teki birinci isim yazilari

Aim: The aim of the study is to investigate the first name publications of the referees of theJournal of the Turkish Association of pediatric Surgeons using electronic database PUBMED. Material and Methods: The first name publications of 124 pediatric surgeons, who are the editorial consultants of the Turkish official pediatric surgery journal "Çocuk Cerrahisi Dergisi" from the beginning to 2006, were investigated by giving the first and family names as search option in PUBMED. The collected data were analysed in detail in regard to total author-publication number, publication journals and chosen topics. Results: There were total 1062 publications. The number of Turkish authors: 1745 (1,6 author/publication), foreign authors: 105 (% 5.6). Publications in the pediatric surgery journals: 516 (% 48.5), publications in 147 non-pediatric surgery journals: 546 (% 51.5). The most common topics were: Gastrointestinal system: 364 (% 34.2), urology: 275 (% 25.8), oncology: 88 (% 8.2), trauma: 84 (% 7.9), abdominal wall: 78 (% 7.3) and infection: 51 (% 4.8). The most common pediatric surgery journals were: J Pediatric Surgery (JPS): 280, European J Pediatr Surg (EJPS): 130, Pediatric Surgery International (PSI): 81. The type of most common non-pediatric surgery journals were: urology: 157, pediatrics: 138, general surgery: 104, research: 22, cardiovascular surgery: 16, general medicine: 14. The most common non-pediatric surgery journals were Turk J Pediatr: 38, Br J Urol: 19, Int Urol Nephrol: 15, BJU Int: 14 and Surg Today: 14. Conclusion: The study demonstrated, that the first name pediatric surgical publications were published in 48.5% in the pediatric surgery journals. The most common published pediatric surgery journal was JPS, the most common non- pediatric surgery journal was Turk J Pediatr and the most common written topic was gastrointestinal system