767 research outputs found
Imprints of deviations from the gravitational inverse-square law on the power spectrum of mass fluctuations
Deviations from the gravitational inverse-square law would imprint
scale-dependent features on the power spectrum of mass density fluctuations. We
model such deviations as a Yukawa-like contribution to the gravitational
potential and discuss the growth function in a mixed dark matter model with
adiabatic initial conditions. Evolution of perturbations is considered in
general non-flat cosmological models with a cosmological constant, and an
analytical approximation for the growth function is provided. The coupling
between baryons and cold dark matter across recombination is negligibly
affected by modified gravity physics if the proper cutoff length of the
long-range Yukawa-like force is > 10 h^{-1} Mpc. Enhancement of gravity affects
the subsequent evolution, boosting large-scale power in a way that resembles
the effect of a lower matter density. This phenomenon is almost perfectly
degenerate in power-spectrum shape with the effect of a background of massive
neutrinos. Back-reaction on density growth from a modified cosmic expansion
rate should however also affect the normalization of the power spectrum, with a
shape distortion similar to the case of a non-modified background.Comment: 8 pages, 7 figures; submitted to MNRA
Socioeconomic inequalities in health among Swedish adolescents - adding the subjective perspective
Abstract Background Socioeconomic inequalities in adolescent health predict future inequalities in adult health. Subjective measures of socioeconomic status (SES) may contribute with an increased understanding of these inequalities. The aim of this study was to investigate socioeconomic health inequalities using both a subjective and an objective measure of SES among Swedish adolescents. Method Cross-sectional HBSC-data from 2002 to 2014 was used with a total sample of 23,088 adolescents aged 11–15 years. Three measures of self-rated health (dependent variables) were assessed: multiple health complaints, life satisfaction and health perception. SES was measured objectively by the Family Affluence Scale (FAS) and subjectively by “perceived family wealth” (independent variables). The trend for health inequalities was investigated descriptively with independent t-tests and the relationship between independent and dependent variables was investigated with multiple logistic regression analysis. Gender, age and survey year was considered as possible confounders. Results Subjective SES was more strongly related to health outcomes than the objective measure (FAS). Also, the relation between FAS and health was weakened and even reversed (for multiple health complaints) when subjective SES was tested simultaneously in regression models (FAS OR: 1.03, CI: 1.00;1.06 and subjective SES OR: 0.66, CI: 0.63;0.68). Conclusions The level of socioeconomic inequalities in adolescent health varied depending on which measure that was used to define SES. When focusing on adolescents, the subjective appraisals of SES is important to consider because they seem to provide a stronger tool for identifying inequalities in health for this group. This finding is important for policy makers to consider given the persistence of health inequalities in Sweden and other high-income countries
Radar remote sensing estimates of waves and wave forcing at a tidal inlet
Author Posting. © American Meteorological Society, 2015. This article is posted here by permission of American Meteorological Society for personal use, not for redistribution. The definitive version was published in Journal of Atmospheric and Oceanic Technology 32 (2015): 842–854, doi:10.1175/JTECH-D-14-00215.1.The time and space variability of wave transformation through a tidal inlet is investigated with radar remote sensing. The frequency of wave breaking and the net wave breaking dissipation at high spatial resolution is estimated using image sequences acquired with a land-based X-band marine radar. Using the radar intensity data, transformed to normalized radar cross section σ0, the temporal and spatial distributions of wave breaking are identified using a threshold developed via the data probability density function. In addition, the inlet bathymetry is determined via depth inversion of the radar-derived frequencies and wavenumbers of the surface waves using a preexisting algorithm (cBathy). Wave height transformation is calculated through the 1D cross-shore energy flux equation incorporating the radar-estimated breaking distribution and bathymetry. The accuracy of the methodology is tested by comparison with in situ wave height observations over a 9-day period, obtaining correlation values R = 0.68 to 0.96, and root-mean-square errors from 0.05 to 0.19 m. Predicted wave forcing, computed as the along-inlet gradient of the cross-shore radiation stress was onshore during high-wave conditions, in good agreement (R = 0.95) with observations.These data were collected as part of a joint field program, Data Assimilation and Remote Sensing for Littoral Applications (DARLA) and Rivers and Inlets (RIVET-1), both funded by the Office of Naval Research. The authors were funded through the Office of Naval Research Grant N00014-10-1-0932 and the Office of the Assistant Secretary of Defense for Research and Engineering.2015-10-0
Artificial Light at Night as a Driver of Evolution Across Urban–Rural Landscapes
Light is fundamental to biological systems, affecting the daily rhythms of bacteria, plants, and animals. Artificial light at night ( ALAN ), a ubiquitous feature of urbanization, interferes with these rhythms and has the potential to exert strong selection pressures on organisms living in urban environments. ALAN also fragments landscapes, altering the movement of animals into and out of artificially lit habitats. Although research has documented phenotypic and genetic differentiation between urban and rural organisms, ALAN has rarely been considered as a driver of evolution. We argue that the fundamental importance of light to biological systems, and the capacity for ALAN to influence multiple processes contributing to evolution, makes this an important driver of evolutionary change, one with the potential to explain broad patterns of population differentiation across urban–rural landscapes. Integrating ALAN ’ s evolutionary potential into urban ecology is a targeted and powerful approach to understanding the capacity for life to adapt to an increasingly urbanized world
Phases of asymmetric nuclear matter with broken space symmetries
Isoscalar Cooper pairing in isospin asymmetric nuclear matter occurs between
states populating two distinct Fermi surfaces, each for neutrons and protons.
The transition from a BCS-like to the normal (unpaired) state, as the isospin
asymmetry is increased, is intervened by superconducting phases which
spontaneously break translational and rotational symmetries. One possibility is
the formation of a condensate with a periodic crystallinelike structure where
Cooper pairs carry net momentum (the nuclear
Larkin-Ovchinnikov-Fulde-Ferrell-phase). Alternatively, perturbations of the
Fermi surfaces away from spherical symmetry allow for minima in the condensate
free energy which correspond to a states with quadrupole deformations of Fermi
surfaces and zero momentum of the Cooper pairs. In a combined treatment of
these phases we show that, although the Cooper pairing with finite momentum
might arise as a local minimum, the lowest energy state features are deformed
Fermi surfaces and Cooper pairs with vanishing total momentum.Comment: 22 pages, 6 figures, RevTex; v2: matches published version; v3:
changes in the frontmatter, content unchange
Purifying Selection in Deeply Conserved Human Enhancers Is More Consistent than in Coding Sequences
(c) 2014 De Silva et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited
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Stops making sense: translational trade-offs and stop codon reassignment
Background
Efficient gene expression involves a trade-off between (i) premature termination of protein synthesis; and (ii) readthrough, where the ribosome fails to dissociate at the terminal stop. Sense codons that are similar in sequence to stop codons are more susceptible to nonsense mutation, and are also likely to be more susceptible to transcriptional or translational errors causing premature termination. We therefore expect this trade-off to be influenced by the number of stop codons in the genetic code. Although genetic codes are highly constrained, stop codon number appears to be their most volatile feature.
Results
In the human genome, codons readily mutable to stops are underrepresented in coding sequences. We construct a simple mathematical model based on the relative likelihoods of premature termination and readthrough. When readthrough occurs, the resultant protein has a tail of amino acid residues incorrectly added to the C-terminus. Our results depend strongly on the number of stop codons in the genetic code. When the code has more stop codons, premature termination is relatively more likely, particularly for longer genes. When the code has fewer stop codons, the length of the tail added by readthrough will, on average, be longer, and thus more deleterious. Comparative analysis of taxa with a range of stop codon numbers suggests that genomes whose code includes more stop codons have shorter coding sequences.
Conclusions
We suggest that the differing trade-offs presented by alternative genetic codes may result in differences in genome structure. More speculatively, multiple stop codons may mitigate readthrough, counteracting the disadvantage of a higher rate of nonsense mutation. This could help explain the puzzling overrepresentation of stop codons in the canonical genetic code and most variants
Upper limits on neutrino masses from the 2dFGRS and WMAP: the role of priors
Solar, atmospheric, and reactor neutrino experiments have confirmed neutrino
oscillations, implying that neutrinos have non-zero mass, but without pinning
down their absolute masses. While it is established that the effect of
neutrinos on the evolution of cosmic structure is small, the upper limits
derived from large-scale structure data could help significantly to constrain
the absolute scale of the neutrino masses. In a recent paper the 2dF Galaxy
Redshift Survey (2dFGRS) team provided an upper limit m_nu,tot < 2.2 eV, i.e.
approximately 0.7 eV for each of the three neutrino flavours, or phrased in
terms of their contributioin to the matter density, Omega_nu/Omega_m < 0.16.
Here we discuss this analysis in greater detail, considering issues of assumed
'priors' like the matter density Omega_m and the bias of the galaxy
distribution with respect the dark matter distribution. As the suppression of
the power spectrum depends on the ratio Omega_nu/Omega_m, we find that the
out-of- fashion Mixed Dark Matter Model, with Omega_nu=0.2, Omega_m=1 and no
cosmological constant, fits the 2dFGRS power spectrum and the CMB data
reasonably well, but only for a Hubble constant H_0<50 km/s/Mpc. As a
consequence, excluding low values of the Hubble constant, e.g. with the HST Key
Project is important in order to get a strong constraint on the neutrino
masses. We also comment on the improved limit by the WMAP team, and point out
that the main neutrino signature comes from the 2dFGRS and the Lyman alpha
forest.Comment: 24 pages, 12 figures Minor changes to matched version published in
JCA
How Are Adolescents Sleeping? Adolescent Sleep Patterns and Sociodemographic Differences in 24 European and North American Countries.
PURPOSE:Insufficient and poor sleep patterns are common among adolescents worldwide. Up to now, the evidence on adolescent sleep has been mostly informed by country-specific studies that used different measures and age groups, making direct comparisons difficult. Cross-national data on adolescent sleep that could inform nations and international discussions are lacking. We examined the sleep patterns of adolescents across 24 countries and by gender, age, and affluence groups. METHODS:We obtained sleep data on 165,793 adolescents (mean age 13.5 years; 50.5% girls) in 24 European and North American countries from the recent cross-sectional Health Behaviour in School-aged Children surveys (2013-2014 and 2017-2018). For each country, we calculated the age-standardized mean in sleep duration, timing, and consistency and the proportions meeting sleep recommendations on school and nonschool days from self-reported bedtimes and wake times. We conducted stratified analyses by gender, age, and family affluence group. RESULTS:Adolescent sleep patterns varied cross-nationally. The average sleep duration ranged between 7:47 and 9:07 hours on school days and between 9:31 and 10:22 hours on nonschool days, and the proportion of adolescents meeting sleep recommendations ranged between 32% and 86% on school days and between 79% and 92% on nonschool days. Sleep patterns by gender and affluence groups were largely similar, but older adolescents slept less and went to bed later on school days than younger adolescents in all countries. CONCLUSIONS:The sleep patterns of adolescents vary across countries and sociodemographic groups. Insufficient sleep on school days is common in many countries. Public health and policy efforts to promote healthy adolescent sleep are encouraged
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