FORMATION OF MUNICIPAL SERVICE HUMAN RESOURCE POTENTIAL AS A STRATEGIC FACTOR FOR RUSSIAN TERRITORY SUSTAINABLE DEVELOPMENT

Purpose: The development of municipal service professional staff units is one of the most significant factors for Russian territory's sustainable development. Methodology: The information base of the research includes the results of sociological studies conducted by the All-Russia Council of Local Self-Government (ARCLSG) through the sending of questionnaires via the Internet: "Human Resources of Municipalities" (June-July 2013, N = 915); "Human Resources of Local Self-Government" (March-April 2016, N = 582). Result: The results of the expert survey showed that the leaders of local authorities are not fully satisfied with the level of municipal employee professional training. Evaluating the effectiveness of training programs implemented in recent years, most experts chose the following answer: "not all of the required issues have been covered, only a few things can be useful in practical activities". In modern conditions, it is necessary to specify the content of education, taking into account the specifics of the territory, its social and economic problems, the overcoming of a narrow theoretical orientation of the courses. Applications: This research can be used for the universities, teachers and education students. Novelty/Originality: In this research, the model of formation of municipal service human resource potential as a strategic factor for Russian territory sustainable development is presented in a comprehensive and complete manner

TOURISM ATTRACTION IN RUSSIAN REGIONS IN CYBERSPACE: NEW TENDENCIES OF TOURISM MEDIA MARKETING

Purpose: The present study was aimed at investigating the characteristics of tourist media content in cyberspace. The characteristics regarding the reflection and survey of tourist attractions in the Russian regions were also analyzed. Methodology: Data on the empirical research field was collected through tourist feedback on the Internet, as well as other social studies studied the wide-ranging relationship of users with media space. Visual media and contemporary time were identified among the most well-known sources of information about services and tourist facilities. Available sentiments with a variety of information available in cyberspace included: inclusive communication, comprehensiveness, pragmatism and using literal communication and providing easy access. In this paper, the outcomes of the outlook for tourism advancement by the help of the media were also discussed. Result: Tourism media, as well as the expansion flow and evolution regarding receiving and construction and increasing the information to respond to the key questions of the development of the tourism industry, were studied such as infrastructure equipment and services and the potential of the tourist industry. The content of cyber media was found to be helpful in consolidating the issues and modes and practical cases of various tourist groups, as well as representing the expectations and interests of tourism industry consumers. The popularity of media content has created vast opportunities for creators and users of information including personalization of demands, flexible communication, and the feasibility of introducing characters by presenting in virtual online space about the time spent on holidays. Applications: This research can be used for the universities, teachers and education students. Novelty/Originality: In this research, the model of the tourist attraction in Russian regions in cyberspace: new tendencies of tourism media marketing is presented in a comprehensive and complete manner

TOURISM ATTRACTION IN RUSSIAN REGIONS IN CYBERSPACE: NEW TENDENCIES OF TOURISM MEDIA MARKETING

Purpose of Study: The present study was aimed at investigating the characteristics of tourist media content in cyberspace. The characteristics regarding the reflection and survey of tourist attractions in the Russian regions were also analyzed. Methodology: Data on the empirical research field was collected through tourist feedback on the Internet, as well as other social studies studied the wide-ranging relationship of users with media space. Visual media and contemporary time were identified among the most well-known sources of information about services and tourist facilities. Available sentiments with a variety of information available in cyberspace included: inclusive communication, comprehensiveness, pragmatism and using literal communication and providing easy access. Result: In this paper, the outcomes of the outlook for tourism advancement by the help of the media were also discussed. Tourism media, as well as the expansion flow and evolution regarding receiving and construction and increasing the information to respond to the key questions of the development of the tourism industry, were studied such as infrastructure equipment and services and the potential of the tourist industry. The content of cyber media was found to be helpful in consolidating the issues and modes and practical cases of various tourist groups, as well as representing the expectations and interests of tourism industry consumers. The popularity of media content has created vast opportunities for creators and users of information including personalization of demands, flexible communication, and the feasibility of introducing characters by presenting in virtual online space about the time spent on holidays

REFLECTION OF LABOR MARKET INTERESTS AND EXPECTATIONS IN EDUCATIONAL ORDER FOR CONTEMPORARY SCHOOL

Purpose of the study: The main objective of the study was the analysis of key labor market request content for the secondary education system, the level of employers' expectations compliance and actual learning outcomes, the research of resources and partnership interaction limitations of all interesting subjects in the process of an educational order development. Methodology: The main method was the questionnaire survey of experts (individual entrepreneurs, the heads of industrial and structural divisions) of Moscow (N = 316). The results of the expert survey showed the interest of employers in close cooperation with school in order to reflect the interests of the labor market in the educational order adequately. Results: The most motivated group is a small business, the leaders of the lowest level in the sphere of trade and service, who directly interact with the school graduates in the process of their early start of labor activity. The experts noted the problems in the development of the social competencies among schoolchildren: excessive self-esteem, an excessive level of claims, low level of willingness to work in a team, the lack of such qualities as responsiveness and responsibility. The cooperation between school and employers is limited to traditional sponsorship practices. The interaction of employers and educational institutions is quite fragmentary, it depends on a variety of random factors (personal and situational motives), which does not ensure the stability and the effectiveness of social partnership. Applications of this study: This research can be used for the universities, teachers, and students. Novelty/Originality of this study: In this research, the model of Reflection of Labor Market Interests and Expectations in Educational Order for Contemporary School is presented in a comprehensive and complete manner

Interação entre as autoridades e o setor sem fins lucrativos na Federação Russa: restrições de recursos e desenvolvimento

The aim of the work is to study the conditions of Russian NPO functioning, the key problems and the trends of their development, and to develop the mechanisms that provide constructive practices for cooperation between the state and the non-profit sector. The results of statistical studies illustrate a high level of territorial differentiation among the representatives of the non-commercial sector, which creates inequality in terms of access to social services, the opportunities to meet the social needs of the population, the development of civil society, the involvement of social groups for the development and the implementation of managerial decisions in the social sphere. A low level of financial and infrastructural security of NPO activities, the lack of voluntary support lead to the reduction of trends and the volume of social assistance for the population. Currently, the interaction of local government and non-profit public organizations is characterized by rather narrow models of cooperation. The leading mechanism that can provide the necessary modernization of non-profit organization activities, the increase of their role and representation in public problem solution, is an intersectoral social partnership that can provide constructive coordination of key agent positions in the social space, an effective interaction of government bodies, population and public organizations.El objetivo del trabajo es estudiar las condiciones de funcionamiento de las OSFL rusas, los problemas clave y las tendencias de su desarrollo, y desarrollar los mecanismos que proporcionan prácticas constructivas para la cooperación entre el estado y el sector sin fines de lucro. Los resultados de los estudios estadísticos ilustran un alto nivel de diferenciación territorial entre los representantes del sector no comercial, que crea desigualdad en términos de acceso a los servicios sociales, las oportunidades para satisfacer las necesidades sociales de la población, el desarrollo de la sociedad civil, la participación de grupos sociales para el desarrollo y la implementación de decisiones gerenciales en el ámbito social. Un bajo nivel de seguridad financiera y de infraestructura de las actividades de OSFL, la falta de apoyo voluntario conducen a la reducción de las tendencias y al volumen de asistencia social para la población. Actualmente, la interacción del gobierno local y las organizaciones públicas sin fines de lucro se caracteriza por modelos de cooperación bastante estrechos. El mecanismo principal que puede proporcionar la modernización necesaria de las actividades de organizaciones sin fines de lucro, el aumento de su función y representación en la solución de problemas públicos, es una asociación social intersectorial que puede proporcionar una coordinación constructiva de puestos de agentes clave en el espacio social, una interacción efectiva de organismos gubernamentales, población y organizaciones públicas.O objetivo do trabalho é estudar as condições operacionais das organizações sem fins lucrativos russas, os principais problemas e tendências de seu desenvolvimento e desenvolver mecanismos que forneçam práticas construtivas de cooperação entre o Estado e o setor sem fins lucrativos. Os resultados dos estudos estatísticos ilustram um alto nível de diferenciação territorial entre os representantes do setor não comercial, o que gera desigualdade em termos de acesso a serviços sociais, oportunidades de atender às necessidades sociais da população, desenvolvimento da sociedade civil , a participação de grupos sociais para o desenvolvimento e implementação de decisões gerenciais no campo social. Um baixo nível de segurança financeira e infraestrutura das atividades da NPO, a falta de apoio voluntário leva à redução de tendências e ao volume de assistência social para a população. Atualmente, a interação do governo local e organizações públicas sem fins lucrativos é caracterizada por modelos de cooperação bastante estreitos. O principal mecanismo que pode proporcionar a necessária modernização das atividades das organizações sem fins lucrativos, o aumento de sua função e representação na solução de problemas públicos, é uma associação social intersetorial que pode proporcionar uma coordenação construtiva de posições de agentes o espaço social, uma interação efetiva de agências governamentais, população e organizações públicas

Supply Chain Infrastructure Development in Russian Economy

Abstract- The article is devoted to the study of the activities of Zemstvo institutions for the development of supply chain infrastructure in the XIX-early XX centuries; identification of the role of the Zemstvo reform in the formation of supply chain infrastructure at the local level. Supply Chain infrastructure provides the means for chain economic entities and firms sharing a common interest to participate in a mutual exchange. Despite the fact that the provision of supply chain services was not among the priorities of the Zemstvos, significant results were achieved. The retrospective analysis allowed us to highlight the advantages and disadvantages of the Zemstvo self-government system. The comparative method helped to identify trends in the financial and economic support of Zemstvo bodies at various stages of the Zemstvo reform, and to analyze key indicators of supply chain infrastructure development. It is concluded that the success of the Zemstvo self-government bodies in the development of supply chain infrastructure was due to the availability of significant organizational resources, ensuring sustainable interaction of Zemstvos with the population, active support for local initiatives and the formation of a system of public control. The authors note that the experience of implementing the principle of consolidation of the main directions of management activities for the development of supply chain infrastructure, formed by local authorities, can be in demand in modern conditions and adapted to the current system of local government in Russia for economy efficiency

Методика оценки премии в сделках слияния и поглощения на развивающихся рынках для частных компаний

Introduction. In the context of globalization of economies mergers and acquisitions (in short M&A) are becoming increasingly important in business, as a strategic development of companies. M&A deals, as a rule, are assessed for their efficiency for acquiring company and/or for target-company. There are a lot of papers and empirical studies on this subject. However, most of them concern public companies with shares listed on the stock exchange.Moreover, in the last decade M&A deals were most typical for private owned companies operating in an emerging capital market. Due to the imperfections of an emerging capital market, lack of available and reliable information about private target-companies, investors need a methodology able to take into account these features of the market, to more reasonably calculate the transaction price and the premium in its structure.Topic. As the object of the study we analyse mergers and acquisitions in the countries of the BRICS group (Brazil, Russia, India, China, South Africa) for 2005–2015.Purpose. The purpose of this study is development of methodological apparatus for assessment of premiums in M&A transactions for private companies in emerging capital markets.Methods. As research methods were used general scientific methods (analysis, synthesis, comparison, graphics), and special ones (statistical analysis methods, the coefficient method).Results. In this article we present the author’s approach to the assessment of fair market value and premiums in M&A transactions with private companies in emerging capital markets. We also conducted testing of proposed methodology.Implementation. The proposed methodology can be used by both external and internal analysts to calculate and justify the premium in deals with private companies in emerging capital markets.Введение. В условиях глобализации экономик сделки слияния и поглощения (mergers and acquisitions, M&A) приобретают все большую актуальность в бизнесе в качестве стратегического развития компаний. Сделки M&A, как правило, оцениваются на предмет их эффективности для компаний-покупателей и/или компанийцелей. Существует достаточно много работ и эмпирических исследований, посвященных данному направлению. Однако большая их часть осуществлена для публичных компаний, имеющих акции, котирующиеся на бирже. При этом в последние десятилетие сделки M&A более актуальны для частных компаний, функционирующих на развивающемся рынке капитала. В силу несовершенства развивающегося рынка капитала, отсутствия доступной и достоверной информации о частной компании-цели инвесторам требуется методика, способная учесть данные особенности рынка, чтобы более обоснованно рассчитать цену сделки и премию в ее структуре.Предмет. В качестве объекта исследования выступили сделки слияний и поглощений в странах группы БРИКС (Бразилия, Россия, Индия, Китай, ЮАР) за 2005–2015 гг.Цель. В этой связи цель работы заключается в разработке методологического аппарата по оценке премий в сделках M&A для частных компаний развивающихся рынков капитала. Методы. В качестве методов исследования использовались как общенаучные методы исследования (анализ, синтез, сравнение, графический), так и специальные (статистические методы анализа, коэффициентный метод).Результаты. В данной статье предложен авторский подход к оценке справедливой рыночной стоимости и премии в сделках M&A с частными компаниями на развивающихся рынках капитала, проведена апробация методики.Область применения результатов. Предложенная методика может быть использована как внешними, так и внутренними аналитиками для расчета и обоснования премии в сделках с частными компаниями на развивающихся рынках капитала

Finding of the Low Molecular Weight Inhibitors of Resuscitation Promoting Factor Enzymatic and Resuscitation Activity

Background: Resuscitation promoting factors (RPF) are secreted proteins involved in reactivation of dormant actinobacteria, including Mycobacterium tuberculosis. They have been considered as prospective targets for the development of new antituberculosis drugs preventing reactivation of dormant tubercle bacilli, generally associated with latent tuberculosis. However, no inhibitors of Rpf activity have been reported so far. The goal of this study was to find low molecular weight compounds inhibiting the enzymatic and biological activities of Rpfs. Methodology/Principal Findings: Here we describe a novel class of 2-nitrophenylthiocyanates (NPT) compounds that inhibit muralytic activity of Rpfs with IC50 1–7 mg/ml. Fluorescence studies revealed interaction of active NPTs with the internal regions of the Rpf molecule. Candidate inhibitors of Rpf enzymatic activity showed a bacteriostatic effect on growth of Micrococcus luteus (in which Rpf is essential for growth protein) at concentrations close to IC50. The candidate compounds suppressed resuscitation of dormant (‘‘non-culturable’’) cells of M. smegmatis at 1 mg/ml or delayed resuscitation of dormant M. tuberculosis obtained in laboratory conditions at 10 mg/ml. However, they did not inhibit growth of active mycobacteria under these concentrations. Conclusions/Significance: NPT are the first example of low molecular weight compounds that inhibit the enzymatic an

Human APP Gene Expression Alters Active Zone Distribution and Spontaneous Neurotransmitter Release at the Drosophila Larval Neuromuscular Junction

This study provides further insight into the molecular mechanisms that control neurotransmitter release. Experiments were performed on larval neuromuscular junctions of transgenic Drosophila melanogaster lines with different levels of human amyloid precursor protein (APP) production. To express human genes in motor neurons of Drosophila, the UAS-GAL4 system was used. Human APP gene expression increased the number of synaptic boutons per neuromuscular junction. The total number of active zones, detected by Bruchpilot protein puncta distribution, remained unchanged; however, the average number of active zones per bouton decreased. These disturbances were accompanied by a decrease in frequency of miniature excitatory junction potentials without alteration in random nature of spontaneous quantal release. Similar structural and functional changes were observed with co-overexpression of human APP and β-secretase genes. In Drosophila line with expression of human amyloid-β42 peptide itself, parameters analyzed did not differ from controls, suggesting the specificity of APP effects.These results confirm the involvement of APP in synaptogenesis and provide evidence to suggest that human APP overexpression specifically disturbs the structural and functional organization of active zone and results in altered Bruchpilot distribution and lowered probability of spontaneous neurotransmitter release