RAMS among patients with virological failure (VL>5.000 copies/ml) amplified and evaluated by genotyping.

<p>RAMS among patients with virological failure (VL>5.000 copies/ml) amplified and evaluated by genotyping.</p

Patients with VL >5.000 copies/ml (N = 55).

<p>Patients with VL >5.000 copies/ml (N = 55).</p

Patient's disposition.

<p>Patient's disposition.</p

Virological failure rates over time in different resource limited settings.

2<p> <b>Ferradini et al. Lancet 2006; 367:1335–42. ³ Ferradini et al. AIDS 2007, 21:2293–2301.</b></p

NNRTI's resistance mutations prevalence.

<p>NNRTI's resistance mutations prevalence.</p

Axial length and refractive error of Col8A1 gene SNPs (rs13095226 and rs669676) genotypes.

<p>(A-B) Axial length showed statistically significant differences between CC/CT vs TT genotypes of rs13095226, whereas no differences were found for Refractive error. (C-D) Axial length and Refractive error (respectively) did not show differences between GG/GA vs AA genotypes of rs669676.</p

Comparison of the genotype frequencies between mCNV and HMnoCNV group.

<p>Comparison of the genotype frequencies between mCNV and HMnoCNV group.</p

Flow chart for the selection of studies according to the criteria of this Meta-analysis.

<p>Flow chart for the selection of studies according to the criteria of this Meta-analysis.</p

Forest plots of the association of polymorphisms and susceptibility to mCNV.

<p>A) Impact of rs669676 in mCNV. B) Impact of rs10033900. C) Impact of rs10468017.</p

Baseline cohort characteristics.

<p>IQR, interquartile range; ART, antiretroviral therapy; BMI, body mass index, ARV, antiretroviral drug.</p