4 research outputs found
ΠΡΠΏΠΎΠ»ΡΠ·ΠΎΠ²Π°Π½ΠΈΠ΅ Π½ΠΈΠ·ΠΊΠΎΠ±Π΅Π»ΠΊΠΎΠ²ΡΡ ΠΎΠ±ΠΎΠ³Π°ΡΠ΅Π½Π½ΡΡ ΠΊΡΠ°Ρ ΠΌΠ°Π»ΠΎΠΌΡΡΠ½ΡΡ ΠΏΡΠΎΠ΄ΡΠΊΡΠΎΠ² Π² Π΄ΠΈΠ΅ΡΠΎΡΠ΅ΡΠ°ΠΏΠΈΠΈ Π±ΠΎΠ»ΡΠ½ΡΡ ΡΠ΅Π½ΠΈΠ»ΠΊΠ΅ΡΠΎΠ½ΡΡΠΈΠ΅ΠΉ Π΄Π΅ΡΠ΅ΠΉ Π² Π²ΠΎΠ·ΡΠ°ΡΡΠ΅ ΡΡΠ°ΡΡΠ΅ 1 Π³ΠΎΠ΄Π°
Background. The nutrition of children with phenylketonuria includes specialized starch-based products, the range of which is constantly expanding. Our aim was to study the safety of the composition of starchy flakes enriched with a complex of fat-soluble vitamins, natural fruit and berry additives used in the food of children with phenylketonuria. Methods. The study included children under the age of 14 years who were compliant with the previously conducted hypophenylalanine diet, without acute infectious, severe somatic or neurological diseases. The investigated products (starch-rye, wheat, and wheat fruit flakes with a complex of provitamin A and vitamin E) were prescribed instead of previously used low-protein confectionery products in the amount of 20β25 g/day for children under 6 years, 30β40 g β for children aged 6 years and over. The products were given with the recommendation to use alternately, with a duration of at least 10 days, totally for 30 days of the study. The safety of the products was assessed by phenylalanine concentration in the blood (determined by the fluorimetric method). In addition, we assessed the organoleptic qualities of the products and the dynamics of physical development of children. Results. The study included 15 children, mean age 4.4 Β± 1.9 years. The initial concentration of phenylalanine in the blood varied from 1.6 to 3.9 mg%, the median β 2.2 mg% (2.0; 2.8). In 30 days after inclusion of starchy flakes in the diet, the content of phenylalanine in the blood did not change and was 2.5 mg% (2.2; 2.7); p = 0.859. The organoleptic properties of the products were rated Β«excellentΒ» by all patients and their parents (in children under 6 years, only according to the parentsβ assessment). The indicators of physical development did not change. There was no adverse events (allergic reactions, dyspepsia, refusal to take food). Conclusion. Introduction of new functional products β low-protein starchy flakes enriched with a vitamin complex and natural fruit and berry additives β in the diet of children with phenylketonuria allows to maintain the level of phenylalanine in the blood at the level of reference values.ΠΠ±ΠΎΡΠ½ΠΎΠ²Π°Π½ΠΈΠ΅. Π ΠΏΠΈΡΠ°Π½ΠΈΠΈ Π΄Π΅ΡΠ΅ΠΉ Ρ ΡΠ΅Π½ΠΈΠ»ΠΊΠ΅ΡΠΎΠ½ΡΡΠΈΠ΅ΠΉ ΡΠΈΡΠΎΠΊΠΎ ΠΈΡΠΏΠΎΠ»ΡΠ·ΡΡΡ ΡΠΏΠ΅ΡΠΈΠ°Π»ΠΈΠ·ΠΈΡΠΎΠ²Π°Π½Π½ΡΠ΅ ΠΏΡΠΎΠ΄ΡΠΊΡΡ Π½Π° ΠΎΡΠ½ΠΎΠ²Π΅ ΠΊΡΠ°Ρ
ΠΌΠ°Π»ΠΎΠ², Π°ΡΡΠΎΡΡΠΈΠΌΠ΅Π½Ρ ΠΊΠΎΡΠΎΡΡΡ
ΠΏΠΎΡΡΠΎΡΠ½Π½ΠΎ ΡΠ°ΡΡΠΈΡΡΠ΅ΡΡΡ.Π¦Π΅Π»Ρ ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΡ β ΠΈΠ·ΡΡΠΈΡΡ Π±Π΅Π·ΠΎΠΏΠ°ΡΠ½ΠΎΡΡΡ ΡΠΎΡΡΠ°Π²Π° Ρ
Π»ΠΎΠΏΡΠ΅Π² ΠΊΡΠ°Ρ
ΠΌΠ°Π»ΠΎΠΌΡΡΠ½ΡΡ
, ΠΎΠ±ΠΎΠ³Π°ΡΠ΅Π½Π½ΡΡ
ΠΊΠΎΠΌΠΏΠ»Π΅ΠΊΡΠΎΠΌ ΠΆΠΈΡΠΎΡΠ°ΡΡΠ²ΠΎΡΠΈΠΌΡΡ
Π²ΠΈΡΠ°ΠΌΠΈΠ½ΠΎΠ², Π½Π°ΡΡΡΠ°Π»ΡΠ½ΡΠΌΠΈ ΠΏΠ»ΠΎΠ΄ΠΎΠ²ΡΠΌΠΈ ΠΈ ΡΠ³ΠΎΠ΄Π½ΡΠΌΠΈ Π΄ΠΎΠ±Π°Π²ΠΊΠ°ΠΌΠΈ, ΠΈΡΠΏΠΎΠ»ΡΠ·ΡΠ΅ΠΌΡΡ
Π² ΠΏΠΈΡΠ΅ Π΄Π΅ΡΠ΅ΠΉ Ρ ΡΠ΅Π½ΠΈΠ»ΠΊΠ΅ΡΠΎΠ½ΡΡΠΈΠ΅ΠΉ.ΠΠ΅ΡΠΎΠ΄Ρ. Π ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΠ΅ Π²ΠΊΠ»ΡΡΠ°Π»ΠΈ Π΄Π΅ΡΠ΅ΠΉ Π² Π²ΠΎΠ·ΡΠ°ΡΡΠ΅ Π΄ΠΎ 14 Π»Π΅Ρ, ΠΊΠΎΠΌΠΏΠ»Π°Π΅Π½ΡΠ½ΡΡ
ΠΊ ΡΠ°Π½Π΅Π΅ ΠΏΡΠΎΠ²ΠΎΠ΄ΠΈΠΌΠΎΠΉ Π³ΠΈΠΏΠΎΡΠ΅Π½ΠΈΠ»Π°Π»Π°Π½ΠΈΠ½ΠΎΠ²ΠΎΠΉ Π΄ΠΈΠ΅ΡΠ΅, Π±Π΅Π· ΠΎΡΡΡΡΡ
ΠΈΠ½ΡΠ΅ΠΊΡΠΈΠΎΠ½Π½ΡΡ
, ΡΡΠΆΠ΅Π»ΡΡ
ΡΠΎΠΌΠ°ΡΠΈΡΠ΅ΡΠΊΠΈΡ
ΠΈΠ»ΠΈ Π½Π΅Π²ΡΠΎΠ»ΠΎΠ³ΠΈΡΠ΅ΡΠΊΠΈΡ
Π·Π°Π±ΠΎΠ»Π΅Π²Π°Π½ΠΈΠΉ. ΠΡΡΠ»Π΅Π΄ΡΠ΅ΠΌΡΠ΅ ΠΏΡΠΎΠ΄ΡΠΊΡΡ β ΠΊΡΠ°Ρ
ΠΌΠ°Π»ΠΎΡΠΆΠ°Π½ΡΠ΅, ΠΏΡΠ΅Π½ΠΈΡΠ½ΡΠ΅ ΠΈ ΠΏΡΠ΅Π½ΠΈΡΠ½ΡΠ΅ ΠΏΠ»ΠΎΠ΄ΠΎΠ²ΠΎ-ΡΠ³ΠΎΠ΄Π½ΡΠ΅ Ρ
Π»ΠΎΠΏΡΡ Ρ ΠΊΠΎΠΌΠΏΠ»Π΅ΠΊΡΠΎΠΌ ΠΏΡΠΎΠ²ΠΈΡΠ°ΠΌΠΈΠ½Π° Π ΠΈ Π²ΠΈΡΠ°ΠΌΠΈΠ½Π° Π β Π½Π°Π·Π½Π°ΡΠ°Π»ΠΈ Π²Π·Π°ΠΌΠ΅Π½ ΠΏΡΠΈΠΌΠ΅Π½ΡΠ²ΡΠΈΡ
ΡΡ ΡΠ°Π½Π΅Π΅ Π½ΠΈΠ·ΠΊΠΎΠ±Π΅Π»ΠΊΠΎΠ²ΡΡ
ΠΊΠΎΠ½Π΄ΠΈΡΠ΅ΡΡΠΊΠΈΡ
ΠΈΠ·Π΄Π΅Π»ΠΈΠΉ Π² ΠΊΠΎΠ»ΠΈΡΠ΅ΡΡΠ²Π΅ 20β25 Π³/ΡΡΡ Π΄Π΅ΡΡΠΌ ΠΌΠ»Π°Π΄ΡΠ΅ 6 Π»Π΅Ρ, ΠΏΠΎ 30β40 Π³ β Π΄Π΅ΡΡΠΌ, Π΄ΠΎΡΡΠΈΠ³ΡΠΈΡ
Π²ΠΎΠ·ΡΠ°ΡΡΠ° ΠΈΠ»ΠΈ ΡΡΠ°ΡΡΠ΅ 6 Π»Π΅Ρ. ΠΡΠΎΠ΄ΡΠΊΡΡ Π²ΡΠ΄Π°Π²Π°Π»ΠΈ Ρ ΡΠ΅ΠΊΠΎΠΌΠ΅Π½Π΄Π°ΡΠΈΠ΅ΠΉ ΠΈΡΠΏΠΎΠ»ΡΠ·ΠΎΠ²Π°ΡΡ ΠΏΠΎΠΎΡΠ΅ΡΠ΅Π΄Π½ΠΎ, ΠΏΡΠΎΠ΄ΠΎΠ»ΠΆΠΈΡΠ΅Π»ΡΠ½ΠΎΡΡΡΡ Π½Π΅ ΠΌΠ΅Π½Π΅Π΅ 10 ΡΡΡ, Π²ΡΠ΅Π³ΠΎ Π½Π° 30 ΡΡΡ ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΡ. ΠΠ΅Π·ΠΎΠΏΠ°ΡΠ½ΠΎΡΡΡ ΠΏΡΠΎΠ΄ΡΠΊΡΠΎΠ² ΠΎΡΠ΅Π½ΠΈΠ²Π°Π»ΠΈ ΠΏΠΎ ΠΊΠΎΠ½ΡΠ΅Π½ΡΡΠ°ΡΠΈΠΈ ΡΠ΅Π½ΠΈΠ»Π°Π»Π°Π½ΠΈΠ½Π° Π² ΠΊΡΠΎΠ²ΠΈ (ΠΎΠΏΡΠ΅Π΄Π΅Π»ΡΠ»ΠΈ ΡΠ»ΡΠΎΡΠΈΠΌΠ΅ΡΡΠΈΡΠ΅ΡΠΊΠΈΠΌ ΠΌΠ΅ΡΠΎΠ΄ΠΎΠΌ). ΠΠΎΠΏΠΎΠ»Π½ΠΈΡΠ΅Π»ΡΠ½ΠΎ ΠΎΡΠ΅Π½ΠΈΠ²Π°Π»ΠΈ ΠΎΡΠ³Π°Π½ΠΎΠ»Π΅ΠΏΡΠΈΡΠ΅ΡΠΊΠΈΠ΅ ΠΊΠ°ΡΠ΅ΡΡΠ²Π° ΠΏΡΠΎΠ΄ΡΠΊΡΠΎΠ² ΠΈ Π΄ΠΈΠ½Π°ΠΌΠΈΠΊΡ ΡΠΈΠ·ΠΈΡΠ΅ΡΠΊΠΎΠ³ΠΎ ΡΠ°Π·Π²ΠΈΡΠΈΡ Π΄Π΅ΡΠ΅ΠΉ.Π Π΅Π·ΡΠ»ΡΡΠ°ΡΡ. Π ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΠ΅ Π²ΠΊΠ»ΡΡΠΈΠ»ΠΈ 15 Π΄Π΅ΡΠ΅ΠΉ, ΡΡΠ΅Π΄Π½ΠΈΠΉ Π²ΠΎΠ·ΡΠ°ΡΡ 4,4Β±1,9 Π³ΠΎΠ΄Π°. ΠΡΡ
ΠΎΠ΄Π½Π°Ρ ΠΊΠΎΠ½ΡΠ΅Π½ΡΡΠ°ΡΠΈΡ ΡΠ΅Π½ΠΈΠ»Π°Π»Π°Π½ΠΈΠ½Π° Π² ΠΊΡΠΎΠ²ΠΈ Π²Π°ΡΡΠΈΡΠΎΠ²Π°Π»Π° ΠΎΡ 1,6 Π΄ΠΎ 3,9 ΠΌΠ³%, ΠΌΠ΅Π΄ΠΈΠ°Π½Π° β 2,2 ΠΌΠ³% (2,0; 2,8). Π§Π΅ΡΠ΅Π· 30 ΡΡΡ ΠΏΠΎΡΠ»Π΅ Π²ΠΊΠ»ΡΡΠ΅Π½ΠΈΡ Π² ΡΠ°ΡΠΈΠΎΠ½ ΠΊΡΠ°Ρ
ΠΌΠ°Π»ΠΎΠΌΡΡΠ½ΡΡ
Ρ
Π»ΠΎΠΏΡΠ΅Π² ΡΠΎΠ΄Π΅ΡΠΆΠ°Π½ΠΈΠ΅ ΡΠ΅Π½ΠΈΠ»Π°Π»Π°Π½ΠΈΠ½Π° Π² ΠΊΡΠΎΠ²ΠΈ Π½Π΅ ΠΈΠ·ΠΌΠ΅Π½ΠΈΠ»ΠΎΡΡ ΠΈ ΡΠΎΡΡΠ°Π²ΠΈΠ»ΠΎ 2,5 ΠΌΠ³% (2,2; 2,7); Ρ=0,859. ΠΡΠ³Π°Π½ΠΎΠ»Π΅ΠΏΡΠΈΡΠ΅ΡΠΊΠΈΠ΅ ΡΠ²ΠΎΠΉΡΡΠ²Π° ΠΏΡΠΎΠ΄ΡΠΊΡΠΎΠ² Π±ΡΠ»ΠΈ ΠΎΡΠ΅Π½Π΅Π½Ρ Π½Π° Β«ΠΎΡΠ»ΠΈΡΠ½ΠΎΒ» Π²ΡΠ΅ΠΌΠΈ ΠΏΠ°ΡΠΈΠ΅Π½ΡΠ°ΠΌΠΈ ΠΈ ΠΈΡ
ΡΠΎΠ΄ΠΈΡΠ΅Π»ΡΠΌΠΈ (Ρ Π΄Π΅ΡΠ΅ΠΉ Π² Π²ΠΎΠ·ΡΠ°ΡΡΠ΅ Π΄ΠΎ 6 Π»Π΅Ρ β ΡΠΎΠ»ΡΠΊΠΎ ΡΠΎΠ³Π»Π°ΡΠ½ΠΎ ΠΎΡΠ΅Π½ΠΊΠ΅ ΡΠΎΠ΄ΠΈΡΠ΅Π»Π΅ΠΉ). ΠΠΎΠΊΠ°Π·Π°ΡΠ΅Π»ΠΈ ΡΠΈΠ·ΠΈΡΠ΅ΡΠΊΠΎΠ³ΠΎ ΡΠ°Π·Π²ΠΈΡΠΈΡ Π½Π΅ ΠΈΠ·ΠΌΠ΅Π½ΠΈΠ»ΠΈΡΡ. ΠΠ΅ΠΆΠ΅Π»Π°ΡΠ΅Π»ΡΠ½ΡΠ΅ ΡΠ²Π»Π΅Π½ΠΈΡ (Π°Π»Π»Π΅ΡΠ³ΠΈΡΠ΅ΡΠΊΠΈΠ΅ ΡΠ΅Π°ΠΊΡΠΈΠΈ, Π΄ΠΈΡΠΏΠ΅ΠΏΡΠΈΠΈ, ΠΎΡΠΊΠ°Π· ΠΎΡ ΠΏΡΠΈΠ΅ΠΌΠ° ΠΏΡΠΎΠ΄ΡΠΊΡΠΎΠ²) Π½Π΅ Π·Π°ΡΠΈΠΊΡΠΈΡΠΎΠ²Π°Π½Ρ.ΠΠ°ΠΊΠ»ΡΡΠ΅Π½ΠΈΠ΅. ΠΠ²Π΅Π΄Π΅Π½ΠΈΠ΅ Π² ΡΠ°ΡΠΈΠΎΠ½ Π΄Π΅ΡΠ΅ΠΉ Ρ ΡΠ΅Π½ΠΈΠ»ΠΊΠ΅ΡΠΎΠ½ΡΡΠΈΠ΅ΠΉ Π½ΠΎΠ²ΡΡ
ΡΡΠ½ΠΊΡΠΈΠΎΠ½Π°Π»ΡΠ½ΡΡ
ΠΏΡΠΎΠ΄ΡΠΊΡΠΎΠ² β Ρ
Π»ΠΎΠΏΡΠ΅Π² ΠΊΡΠ°Ρ
ΠΌΠ°Π»ΠΎΠΌΡΡΠ½ΡΡ
Π½ΠΈΠ·ΠΊΠΎΠ±Π΅Π»ΠΊΠΎΠ²ΡΡ
, ΠΎΠ±ΠΎΠ³Π°ΡΠ΅Π½Π½ΡΡ
Π²ΠΈΡΠ°ΠΌΠΈΠ½Π½ΡΠΌ ΠΊΠΎΠΌΠΏΠ»Π΅ΠΊΡΠΎΠΌ ΠΈ Π½Π°ΡΡΡΠ°Π»ΡΠ½ΡΠΌΠΈ ΠΏΠ»ΠΎΠ΄ΠΎΠ²ΡΠΌΠΈ ΠΈ ΡΠ³ΠΎΠ΄Π½ΡΠΌΠΈ Π΄ΠΎΠ±Π°Π²ΠΊΠ°ΠΌΠΈ, ΠΏΠΎΠ·Π²ΠΎΠ»ΡΠ΅Ρ ΡΠΎΡ
ΡΠ°Π½ΡΡΡ ΡΡΠΎΠ²Π΅Π½Ρ ΡΠ΅Π½ΠΈΠ»Π°Π»Π°Π½ΠΈΠ½Π° Π² ΠΊΡΠΎΠ²ΠΈ Π½Π° ΡΡΠΎΠ²Π½Π΅ ΡΠ΅ΡΠ΅ΡΠ΅Π½ΡΠ½ΡΡ
Π·Π½Π°ΡΠ΅Π½ΠΈΠΉ.ΠΠ‘Π’ΠΠ§ΠΠΠ Π€ΠΠΠΠΠ‘ΠΠ ΠΠΠΠΠΠ― Π Π°Π±ΠΎΡΠ° Π²ΡΠΏΠΎΠ»Π½Π΅Π½Π° ΠΏΡΠΈ ΠΏΠΎΠ΄Π΄Π΅ΡΠΆΠΊΠ΅ Π³ΡΠ°Π½ΡΠ° Π€Π΅Π΄Π΅ΡΠ°Π»ΡΠ½ΠΎΠ³ΠΎ Π³ΠΎΡΡΠ΄Π°ΡΡΡΠ²Π΅Π½Π½ΠΎΠ³ΠΎ Π½Π°ΡΡΠ½ΠΎΠ³ΠΎ ΡΡΡΠ΅ΠΆΠ΄Π΅Π½ΠΈΡ Β«ΠΡΠ΅ΡΠΎΡΡΠΈΠΉΡΠΊΠΈΠΉ Π½Π°ΡΡΠ½ΠΎ-ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°ΡΠ΅Π»ΡΡΠΊΠΈΠΉ ΠΈΠ½ΡΡΠΈΡΡΡ ΠΊΡΠ°Ρ
ΠΌΠ°Π»ΠΎΠΏΡΠΎΠ΄ΡΠΊΡΠΎΠ²Β» Π€Π΅Π΄Π΅ΡΠ°Π»ΡΠ½ΠΎΠ³ΠΎ Π°Π³Π΅Π½ΡΡΡΠ²Π° Π½Π°ΡΡΠ½ΡΡ
ΠΎΡΠ³Π°Π½ΠΈΠ·Π°ΡΠΈΠΉ (ΠΠΎΡΠΊΠΎΠ²ΡΠΊΠ°Ρ ΠΎΠ±Π»Π°ΡΡΡ). ΠΠ»Ρ ΡΠ΅Π»Π΅ΠΉ ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΡ ΠΈΡΠΏΠΎΠ»ΡΠ·ΠΎΠ²Π°Π»ΠΈΡΡ ΠΏΡΠΎΠ΄ΡΠΊΡΡ, Π±Π΅Π·Π²ΠΎΠ·ΠΌΠ΅Π·Π΄Π½ΠΎ ΠΏΡΠ΅Π΄ΠΎΡΡΠ°Π²Π»Π΅Π½Π½ΡΠ΅ ΠΏΡΠΎΠΈΠ·Π²ΠΎΠ΄ΠΈΡΠ΅Π»Π΅ΠΌ (ΠΎΠΏΡΡΠ½ΠΎΠ΅ ΠΏΡΠΎΠΈΠ·Π²ΠΎΠ΄ΡΡΠ²ΠΎ Π€ΠΠΠ£ Β«ΠΠΠΠΠΒ» Π€ΠΠΠ).ΠΠΠΠ€ΠΠΠΠ’ ΠΠΠ’ΠΠ ΠΠ‘ΠΠ Π’.Π. ΠΠΎΡΠΎΠ²ΠΈΠΊ, Π.Π. Π‘Π΅ΠΌΡΠ½ΠΎΠ²Π°, Π.Π. ΠΡΠΊΠΎΡΠ½ΠΎΠ²Π°, Π.Π. ΠΠ²ΠΎΠ½ΠΊΠΎΠ²Π°, Π’.Π. ΠΡΡΡΠ΅Π²Π°, Π’.Π. Π‘ΡΠ΅ΠΏΠ°Π½ΠΎΠ²Π°, Π.Π. Π‘ΠΊΠ²ΠΎΡΡΠΎΠ²Π° β ΠΏΡΠΎΠ²Π΅Π΄Π΅Π½ΠΈΠ΅ Π½Π°ΡΡΠ½ΠΎ-ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°ΡΠ΅Π»ΡΡΠΊΠΈΡ
ΡΠ°Π±ΠΎΡ ΠΏΡΠΈ ΠΏΠΎΠ΄Π΄Π΅ΡΠΆΠΊΠ΅ ΠΊΠΎΠΌΠΏΠ°Π½ΠΈΠΉ Heinz, Semper, Π₯ΠΈΠΏΡΠΎΠΊΠ° ΠΡΡΡΠΈΡΠΈΠΎΠ½ ΠΡΡ ΠΠΈΠΌΠΈΡΠ΅Π΄. Π.Π. ΠΡΡΠ΅Π²Π°, Π.Π. Π ΠΎΡΠ»Π°Π²ΡΠ΅Π²Π°, Π.Π. ΠΠ΅Π²ΠΎΡΠΊΡΠ½, Π‘.Π’. ΠΡΠΊΠΎΠ²Π°, Π’.Π. ΠΠ°Π»ΠΈΠ½ΠΈΠ½Π°, Π‘.Π. ΠΠ°Π»ΠΈΠ½Π΅Π½ΠΊΠΎΠ²Π° ΠΏΠΎΠ΄ΡΠ²Π΅ΡΠ΄ΠΈΠ»ΠΈ ΠΎΡΡΡΡΡΡΠ²ΠΈΠ΅ ΠΊΠΎΠ½ΡΠ»ΠΈΠΊΡΠ° ΠΈΠ½ΡΠ΅ΡΠ΅ΡΠΎΠ².ΠΠ«Π ΠΠΠΠΠΠ ΠΠ ΠΠΠΠΠ’ΠΠΠ¬ΠΠΠ‘Π’Π ΠΡΡΠ°ΠΆΠ°Π΅ΠΌ Π±Π»Π°Π³ΠΎΠ΄Π°ΡΠ½ΠΎΡΡΡ ΠΊ.ΠΌ.Π½. Π‘.Π. ΠΠ°Π»ΠΈΠ½Π΅Π½ΠΊΠΎΠ²ΠΎΠΉ (ΠΠΎΡΠΊΠΎΠ²ΡΠΊΠΈΠΉ ΠΎΠ±Π»Π°ΡΡΠ½ΠΎΠΉ Π½Π°ΡΡΠ½ΠΎ-ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°ΡΠ΅Π»ΡΡΠΊΠΈΠΉ ΠΊΠ»ΠΈΠ½ΠΈΡΠ΅ΡΠΊΠΈΠΉ ΠΈΠ½ΡΡΠΈΡΡΡ ΠΈΠΌ. Π.Π€. ΠΠ»Π°Π΄ΠΈΠΌΠΈΡΡΠΊΠΎΠ³ΠΎ) Π·Π° ΡΡΠ°ΡΡΠΈΠ΅ Π² Π²ΡΠΏΠΎΠ»Π½Π΅Π½ΠΈΠΈ Π»Π°Π±ΠΎΡΠ°ΡΠΎΡΠ½ΠΎΠΉ ΡΠ°ΡΡΠΈ Π΄Π°Π½Π½ΠΎΠ³ΠΎ ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΡ.Β
COMPLEMENTARY FEEDING, PECULIARITIES OF INTRODUCTION. CLINICAL CASES
The article presents modern, scientifically substantiated approaches to the introduction of complementary feeding in healthy breastfed infants as well as in infants with overweight and various diseases β atopic dermatitis (food allergy), protein-energy deficiency in the context of chronic cardiovascular insufficiency syndrome, neurological disorders, celiac disease. The peculiarities of various complementary foods are demonstrated in clinical examples
Use of Low-Protein Enriched Starch Products in Diet Therapy of Children With Phenylketonuria Aged Over One Year
Background. The nutrition of children with phenylketonuria includes specialized starch-based products, the range of which is constantly expanding. Our aim was to study the safety of the composition of starchy flakes enriched with a complex of fat-soluble vitamins, natural fruit and berry additives used in the food of children with phenylketonuria. Methods. The study included children under the age of 14 years who were compliant with the previously conducted hypophenylalanine diet, without acute infectious, severe somatic or neurological diseases. The investigated products (starch-rye, wheat, and wheat fruit flakes with a complex of provitamin A and vitamin E) were prescribed instead of previously used low-protein confectionery products in the amount of 20β25 g/day for children under 6 years, 30β40 g β for children aged 6 years and over. The products were given with the recommendation to use alternately, with a duration of at least 10 days, totally for 30 days of the study. The safety of the products was assessed by phenylalanine concentration in the blood (determined by the fluorimetric method). In addition, we assessed the organoleptic qualities of the products and the dynamics of physical development of children. Results. The study included 15 children, mean age 4.4 Β± 1.9 years. The initial concentration of phenylalanine in the blood varied from 1.6 to 3.9 mg%, the median β 2.2 mg% (2.0; 2.8). In 30 days after inclusion of starchy flakes in the diet, the content of phenylalanine in the blood did not change and was 2.5 mg% (2.2; 2.7); p = 0.859. The organoleptic properties of the products were rated Β«excellentΒ» by all patients and their parents (in children under 6 years, only according to the parentsβ assessment). The indicators of physical development did not change. There was no adverse events (allergic reactions, dyspepsia, refusal to take food). Conclusion. Introduction of new functional products β low-protein starchy flakes enriched with a vitamin complex and natural fruit and berry additives β in the diet of children with phenylketonuria allows to maintain the level of phenylalanine in the blood at the level of reference values