Her Time, His Time, or the Maid's Time: An Analysis of the Demand for Domestic Work

This paper analyzes households' demand for time inputs to domestic services, modeling simultaneously the decision to purchase services in the market and the time spent on weekend and weekday days by each partner on routine household chores. By focusing on cleaning, laundry, and ironing, we reduce the likelihood that preferences matter and increase the overlap with market services. Particular emphasis is placed on estimating the effects of prices, as captured by own and partner wages and the market price for domestic services. We exploit time-diary data for Great Britain and France, relying on cross-country comparisons to generalize our findings. The results indicate that prices strongly influence market purchases, and that maid service is a closer substitute for household time on weekends than weekdays, but is also correlated with 'her' weekday time. More generally, we find that women's wages have a stronger association with the inputs to domestic work than any other price measure.time use, domestic work, gender

Exact solution of a model of time-dependent evolutionary dynamics in a rugged fitness landscape

A simplified form of the time dependent evolutionary dynamics of a quasispecies model with a rugged fitness landscape is solved via a mapping onto a random flux model whose asymptotic behavior can be described in terms of a random walk. The statistics of the number of changes of the dominant genotype from a finite set of genotypes are exactly obtained confirming existing conjectures based on numerics.Comment: 5 pages RevTex 2 figures .ep

Analytic approach to the evolutionary effects of genetic exchange

We present an approximate analytic study of our previously introduced model of evolution including the effects of genetic exchange. This model is motivated by the process of bacterial transformation. We solve for the velocity, the rate of increase of fitness, as a function of the fixed population size, $N$. We find the velocity increases with $\ln N$, eventually saturated at an $N$ which depends on the strength of the recombination process. The analytical treatment is seen to agree well with direct numerical simulations of our model equations

Damping of sound waves in superfluid nucleon-hyperon matter of neutron stars

We consider sound waves in superfluid nucleon-hyperon matter of massive neutron-star cores. We calculate and analyze the speeds of sound modes and their damping times due to the shear viscosity and non-equilibrium weak processes of particle transformations. For that, we employ the dissipative relativistic hydrodynamics of a superfluid nucleon-hyperon mixture, formulated recently [M.E. Gusakov and E.M. Kantor, Phys. Rev. D78, 083006 (2008)]. We demonstrate that the damping times of sound modes calculated using this hydrodynamics and the ordinary (nonsuperfluid) one, can differ from each other by several orders of magnitude.Comment: 15 pages, 5 figures, Phys. Rev. D accepte

Overweight and obese patients with nickel allergy have a worse metabolic profile compared to weight matched non-allergic individuals

A lack of balance between energy intake and expenditure due to overeating or reduced physical activity does not seem to explain entirely the obesity epidemic we are facing, and further factors are therefore being evaluated. Nickel (Ni) is a ubiquitous heavy metal implied in several health conditions. Regarding this, the European Food Safety Authority has recently released an alert on the possible deleterious effects of dietary Ni on human health given the current levels of Ni dietary intake in some countries. Pre-clinical studies have also suggested its role as an endocrine disruptor and have linked its exposure to energy metabolism and glucose homeostasis dysregulation. Ni allergy is common in the general population, but preliminary data suggest it being even more widespread among overweight patients. OBJECTIVES: The aim of this study has been to evaluate the presence of Ni allergy and its association with the metabolic and endocrine profile in overweight and obese individuals. METHODS: We have evaluated 1128 consecutive overweight and obese outpatients. 784 were suspected of being allergic to Ni and 666 were assessed for it. Presence of Ni allergy and correlation with body mass index (BMI), body composition, metabolic parameters and hormonal levels were evaluated. RESULTS: We report that Ni allergy is more frequent in presence of weight excess and is associated with worse metabolic parameters and impaired Growth Hormone secretion. CONCLUSIONS: We confirm that Ni allergy is more common in obese patients, and we report for the first time its association with worse metabolic parameters and impaired function of the GH-IGF1 axis in human subjects

Impairment of the autophagic flux in astrocytes intoxicated by trimethyltin

Autophagy is a lysosomal catabolic route for protein aggregates and damaged organelles which in different stress conditions, such as starvation, generally improves cell survival. An impairment of this degradation pathway has been reported to occur in many neurodegenerative processes. Trimethyltin (TMT) is a potent neurotoxin present as an environmental contaminant causing tremors, seizures and learning impairment in intoxicated subjects. The present data show that in rat primary astrocytes autophagic vesicles (AVs) appeared after few hours of TMT treatment. The analysis of the autophagic flux in TMT-treated astrocytes was consistent with a block of the late stages of autophagy and was accompanied by a progressive accumulation of the microtubule associated protein light chain 3 (LC3) and of p62/SQSTM1. Interestingly, an increased immunoreactivity for p62/SQSTM1 was also observed in hippocampal astrocytes detected in brain slices of TMT-intoxicated rats. The time-lapse recordings of AVs in EGFP-mCherry-LC3B transfected astrocytes demonstrated a reduced mobility of autophagosomes after TMT exposure respect to control cells. The observed block of the autophagic flux cannot be overcome by known autophagy inducers such as rapamycin or 0.5mM lithium. Although ineffective when used at 0.5mM, lithium at higher concentrations (2mM) was able to protect astrocyte cultures from TMT toxicity. This effect correlated well with its ability to determine the phosphorylation/inactivation of glycogen kinase synthase-3β (GSK-3β)

Three-dimensional matter-wave vortices in optical lattices

We predict the existence of spatially localized nontrivial vortex states of a Bose-Einstein condensate with repulsive atomic interaction confined by a three-dimensional optical lattice. Such vortex-like structures include planar vortices, their co- and counter-rotating bound states, and distinctly three-dimensional non-planar vortex states. We demonstrate numerically that many of these vortex structures are remarkably robust, and therefore can be generated and observed in experiment.Comment: 4 pages, 6 figure