Supp_Figure_2 – Supplemental material for Poor sensitivity of transvaginal ultrasound markers in diagnosis of superficial endometriosis of the uterosacral ligaments

<p>Supplemental material, Supp_Figure_2 for Poor sensitivity of transvaginal ultrasound markers in diagnosis of superficial endometriosis of the uterosacral ligaments by Alice J Robinson, Luk Rombauts, Alex Ades, Kenneth Leong, Eldho Paul and Sofie Piessens in Journal of Endometriosis and Pelvic Pain Disorders</p

Supp_Figure_1 – Supplemental material for Poor sensitivity of transvaginal ultrasound markers in diagnosis of superficial endometriosis of the uterosacral ligaments

<p>Supplemental material, Supp_Figure_1 for Poor sensitivity of transvaginal ultrasound markers in diagnosis of superficial endometriosis of the uterosacral ligaments by Alice J Robinson, Luk Rombauts, Alex Ades, Kenneth Leong, Eldho Paul and Sofie Piessens in Journal of Endometriosis and Pelvic Pain Disorders</p

Characteristics at ICU discharge.

<p>Characteristics at ICU discharge.</p

Comparisons of incidence in delay in relation to admitting units.

<p>Comparisons of incidence in delay in relation to admitting units.</p

Comparisons of duration of delay, reasons for delay and discharge decision revoked.

<p>Comparisons of duration of delay, reasons for delay and discharge decision revoked.</p

Incidence of delirium after ICU discharge decision to 48 hours in ward.

<p>Incidence of delirium after ICU discharge decision to 48 hours in ward.</p

Comparison of patient characteristics between patients with and without delay in discharge at the time of admission to intensive care units.

<p>Comparison of patient characteristics between patients with and without delay in discharge at the time of admission to intensive care units.</p

Oral administration of oxalate-enriched spinach extract as an improved methodology for the induction of dietary hyperoxaluric nephrocalcinosis in experimental rats

<p>Experimental induction of hyperoxaluria by ethylene glycol (EG) administration is disapproved as it causes metabolic acidosis while the oral administration of chemically synthesized potassium oxalate (KOx) diet does not mimic our natural system. Since existing models comprise limitations, this study is aimed to develop an improved model for the induction of dietary hyperoxaluria, and nephrocalcinosis in experimental rats by administration of naturally available oxalate rich diet. Male albino Wistar rats were divided into five groups. Group I, control; group II rats received 0.75% EG, group III rats fed with 5% KOx diet and group IV and V rats were administered with spinach extract of 250 and 500 mg soluble oxalate/day respectively, for 28 d. Urine and serum biochemistry were analyzed. After the experimental period, rats were sacrificed, liver and kidney tissue homogenates were used for antioxidant and lipid peroxidation assay. Relative change in expression of kidney injury molecule-1 (<i>KIM-1</i>) and crystal modulators genes in kidney tissues were evaluated. Tissue damage was assessed by histology studies of liver and kidney. Experimental group rats developed hyperoxaluria and crystalluria. Urine parameters, serum biochemistry, antioxidant profile, lipid peroxidation levels and gene expression analysis of experimental group II and III rats reflected acute kidney damage compared to group V rats. Histopathology results showed moderate hyperplasia in liver and severe interstitial inflammation in kidneys of group II and III than group V rats. Ingestion of naturally available oxalate enriched spinach extract successfully induced dietary hyperoxaluria and nephrocalcinosis in rats with minimal kidney damage.</p

Description of patient recruitment.

<p>Description of patient recruitment.</p

Antioxidant activity of phenolic compounds from extracts of <i>Eucalyptus globulus</i> and <i>Melaleuca styphelioides</i> and their protective role on D-glucose-induced hyperglycemic stress and oxalate stress in NRK-49Fcells

<p>Phytochemicals serve as potential therapeutic agents for the prevention and treatment of diseases. In this study, we elucidate the renoprotective activity of compounds isolated from <i>Eucalyptus globulus</i> and <i>Melaleuca styphelioides</i> extracts in glucose- and oxalate-challenged NRK-49F cell model. The antioxidant potential of isolated compounds was evaluated based on their effect on antioxidant enzyme activities and lipid peroxidation levels. The results demonstrated that exposure of NRK-49F cells to glucose and oxalate stress augmented cell damage and attenuated antioxidant enzyme activities. The phytochemicals 2,2,8-trimethyl-6-formyl-chrom-3-ene-7-<i>O</i>-β-D-glucopyranoside, Cornusiin B and tellimagrandin I treatment restored antioxidant enzyme activity, significantly lowered lipid peroxidation levels and effectively protected cells from glucose and oxalate stress equivalent to the known antioxidant, <i>N</i>-acetyl cysteine. Pterocarinin A significantly reversed cellular damage owing to glucose stress. In conclusion, the compounds isolated from <i>E. globulus</i> and <i>M. styphelioides</i> showed potential cytoprotective and anti-oxidative property against glucose- and oxalate-induced oxidative stress in NRK-49F cells.</p