Finishing the euchromatic sequence of the human genome

The sequence of the human genome encodes the genetic instructions for human physiology, as well as rich information about human evolution. In 2001, the International Human Genome Sequencing Consortium reported a draft sequence of the euchromatic portion of the human genome. Since then, the international collaboration has worked to convert this draft into a genome sequence with high accuracy and nearly complete coverage. Here, we report the result of this finishing process. The current genome sequence (Build 35) contains 2.85 billion nucleotides interrupted by only 341 gaps. It covers ∼99% of the euchromatic genome and is accurate to an error rate of ∼1 event per 100,000 bases. Many of the remaining euchromatic gaps are associated with segmental duplications and will require focused work with new methods. The near-complete sequence, the first for a vertebrate, greatly improves the precision of biological analyses of the human genome including studies of gene number, birth and death. Notably, the human enome seems to encode only 20,000-25,000 protein-coding genes. The genome sequence reported here should serve as a firm foundation for biomedical research in the decades ahead

A note on Rafinesque\u27s florula Columbica

Volume: 56Start Page: 57End Page: 6

Notes on Fraxinus (Ash) in the United States

Volume: 42Start Page: 369End Page: 8

North American Trees With Relationships in Eastern Asia

Volume: 70Start Page: 605End Page: 61

New tree species from Esmeraldas, Ecuador

Volume: 19Start Page: 251End Page: 26

Nomina conservanda proposals for families of seed plants

Volume: 39Start Page: 323End Page:

New tree species from Esmeraldas, Ecuador (Continued)

Volume: 18Start Page: 457End Page: 47

Mapping ranges of the trees of the United States

Volume: 53Start Page: 195End Page: 20

Name of the wild dilly of Florida

Volume: 49Start Page: 289End Page: 29