Surface and subsurface structures of Kalabsha area, southern Egypt, from remote sensing, aeromagnetic and gravity data

AbstractKalabsha area is known to be the most seismo-active zone at the southwestern region of the Aswan High Dam, in southern Egypt. The main purpose of this work is the analysis and interpretation of satellite imagery, aeromagnetic and ground gravity data of Kalabsha area in order to reveal the subsurface lithology and structure. The Landsat ETM+ data were produced in a false-color composite image (bands 1, 2 and 3 in RGB) at the same scale as the geological map in order to reveal some extra geological and structural features.An attempt has been made to analyse the complex nature of gravity and magnetic anomalies over the Kalabsha area to reveal their relationship with surface geology, structure and tectonics setting. These analyses include isolation of anomalies into regional and residual components using the band-pass filter, second vertical derivatives (SVD), upward continuation, and shadowgrams technique. It was noticed that, there is close correlation between gravity, magnetic and many of the major surface geological features of the region. The basement structural map of Kalabsha area has been prepared from the integration of SVD of regional component maps of both gravity and magnetic.The interpretation of the basement tectonic map of the area indicated the presence of two sets of faults NNW–SSE to N–S which is dissected by an E–W to WNW–ESE fault system. These two sets of fault systems as deduced from the gravity and aeromagnetic data were found to match well with that obtained from the Landsat image and geological map

Establishment of two cell lines from embryonic cells of Pectinophora gossypiella (Lepidoptera : Gelichiidae)

Two cell lines from the most important insect pest of cotton, #Pectinophora gossypiella S., were obtained from an embryonic tissue culture. The cells were cultured in GRACE's modified medium. The first cell line, designated ORS-PgS (PgS), was obtained by selecting the non-adherent cells during subculturing and consisted of a homogeneous population of rounded cells. The second cell line, designated ORS-PgA (PgA), obtained without any artificial selection, was a heterogeneous population of spherical and spindle-shaped cells with a great capacity to adhere. The two cell lines had a doubling time of 40 and 48 h respectively and were sub-cultured for more than 50 passages. Their polypeptidic profiles appeared identical but were different from those of other lepidopteran cell lines tested. The two cell lines support the multiplication of #Autographa california nucleopolyhedrovirus, producing 100000 plaque forming units/ml. In 1 to 2% PgS cells, polyhedra were synthetized, whereas PgA cells multiplied only virions. (Résumé d'auteur

Association between polymorphisms of SLC6A3 and DRD1 genes and autism among Saudi Arabia Taif population using PCR-restriction fragment length polymorphism (PCR- RFLP)

The prevalence of autism in Saudi Arabia is 18 per 10,000, higher than the 13 per 10,000 reported in developed  countries. The etiology of autism is still not completely understood. Different studies support the involvement  of dopaminergic neurotransmitter system in the etiology of autism. Several lines of evidences suggest the role of some dopamine related genes, such as DRD1 and SLC6A3 in the etiology of autism. The aim of the present  work was to study the possible role of rs2550936 A/C polymorphism at SLC6A3 locus as well as rs4532 A/G  polymorphism at DRD1 locus in the etiology of autism among Saudi population. The polymorphisms of DRD1  and LC6A3 were genotyped in the case-control study using polymerase chain reaction-restriction fragment  length polymorphism (PCR-RFLP) technique. Significant association as risk factor was found between autism  and GA genotype of DRD1 [OR = 3.5 CI (1.04, 12.41*)] as well as CA genotype of SLC6A3 [OR = 2.53 CI  (1.03, 6.26*)], while CC genotype of SLC6A3 revealed protective effect. In conclusion, possible risk  genotypes  for autism in the DRD1 and SLC6A3 genes were observed. This is the first report in Saudi Arabia  population and Arab world. Therefore further investigations of these markers and other SNPs of SLC6A3 and  DRD1 genes are considered in large replication samples with other causal factors to enable positive  identification of risk genotypes and generalize obtained results.Key words: Etiology, polymorphism, autism, genotype

Sense of Coherence and Gambling: Exploring the Relationship Between Sense of Coherence, Gambling Behaviour and Gambling-Related Harm

Understanding why some people experience problems with gambling whilst others are able to restrict gambling to recreational levels is still largely unexplained. One potential explanation is through salutogenesis, which is a health promotion approach of understanding factors which move people towards health rather than disease. An important aspect of salutogenesis is sense of coherence. Individuals with stronger sense of coherence perceive their environment as comprehensible, manageable and meaningful. The present study examined the relationship of individuals’ sense of coherence on their gambling behaviour and experience of gambling related harm. This exploratory study utilised an archival dataset (n = 1236) from an online, cross sectional survey of people who had experienced negative consequences from gambling. In general, a stronger sense of coherence was related to lower problem gambling severity. When gambling behaviour was controlled for, sense of coherence was significantly related to the experience of individual gambling harms. A strong sense of coherence can be seen as a protective factor against problematic gambling behaviour, and subsequent gambling related harms. These findings support the value of both primary and tertiary prevention strategies that strengthen sense of coherence as a harm minimisation strategy. The present study demonstrates the potential value of, and provides clear direction for, considering sense of coherence in order to understand gambling-related issues.This study was funded by the Victorian Responsible Gambling Foundation, Grant VRGF1-13

Clastogenic Effects of cis-diamminedichloroplatinum. I. Induction of Chromosomal Aberrations in Somatic and Germinal Cells of Mice.

The clastogenicity of cisplatin, cis-diamminedichloroplatinum(II), an extensively used antitumor drug, has been studied employing (101/E1 × C3H/E1)F1 mice, aged 12–14 weeks. Chromosomal aberrations were assessed in mitotic divisions of bone marrow cells and differentiating spermatogonia. The drug was tested at 3 doses, 0.5, 1.0 and 2.5 mg/kg and 1.0, 2.5 and 5.0 mg/kg, respectively, for bone marrow and spermatogonia. Cisplatin had a clastogenic effect which was dose-dependent in both cell types. The frequencies of aberrant cell increased non-linearly in bone marrow and the dose-response relationship could be best described by a linear-quadratic equation. At the highest dose the affected cells carried multiple aberrations. An average of 2.7 aberrations per aberrant cell was observed 12 h after treatment of the mice with 2.5 mg/kg of cisplatin. In differentiating spermatogonia the dose response for aberrant cells could be described by a linear equation. The damage to the individual affected cell was less dramatic than in bone marrow, averaging 1.4 aberrations per damaged cell at the highest dose tested. Gaps were excluded from these considerations but they generally also showed a dose-related increase. A quantitative comparison of the clastogenic response to cisplatin was based on the dose-response relationships using 2 criteria, the doubling dose and the dose of unit increase (DUI). For both comparisons the general conclusion was that bone marrow cells were twice as sensitive as differentiating spermatogonia to the clastogenic action of cisplatin

Yield and activity of Autographa californica multicapsid nucleopolyhedrovirus and Phthorimaea operculella granulosis virus in cloned and uncloned cell lines of P. operculella

Plusieurs lignées, établies à partir d'embryons de #Phthorimae operculella ont été caractérisées : 3 lignées sélectionées, 2 lignées clonées et 3 lignées non sélectionées. Toutes les lignées, présentant des caractéristiques morphologiques, biochimiques différentes, multiplient le virus de #Autographa californica ((AcMNPV). Les lignées clonées le produisent à un plus haut niveau que les cellules parentales (TCID.50 et PIB), voisin de celui de la lignée de référence Sf9. La lignée Pop cl 2B, clonée, produit en outre une quantité détectable d'ADN de la granulose de #P. operculella$. Seule la lignée ORS-Pop-95 permet une multiplication complète de ce virus. La comparaison entre ces lignées, dans lesquelles une multiplication différentielle de ces Baculovirus intervient, peut offrir certaines lumières sur la barrière moléculaire qui restreint le spectre d'hôtes de ces virus. Elles peuvent en outre servir de modèles pour des essais de recombinaisons génétiques in vitro afin d'améliorer le spectre d'hôtes. (Résumé d'auteur

Clastogenic effects of acrylamide in mouse bone marrow cells.

Acrylamide, known to induce dominant-lethal mutations (Shelby et al., 1986; Smith et al., 1986) and heritable translocations (Shelby et al., 1987) in rodent germ cells, was hitherto a questionable clastogen in rodent bone marrow (Shiraishi, 1978). Therefore, it was tested for chromosomal aberrations in mouse bone marrow cells, spermatogonia and by the micronucleus test. The intraperitoneally injected doses ranged from 50 to 150 mg/kg. In the chromosomal bone marrow test and the micronucleus assay positive results were obtained with acrylamide, and in the latter test the effect increased linearly with dose. Chromosomal aberrations were not induced in differentiating spermatogonia by the acute acrylamide treatment. Cisplatin was used as a positive control and gave the expected positive response in all 3 tests. The present results demonstrate that acrylamide is no exception among clastogens. It breaks chromosomes not only in mammalian germ cells but also in somatic cells