1,249 research outputs found

    A metric uniformizing model for the Quasi-Fuchsian space

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    We introduce and study a novel uniformization metric model for the quasi-Fuchsian space QF(S) of a closed oriented surface S, defined through a class of C-valued bilinear forms on S, called Bers metrics, which coincide with hyperbolic Riemannian metrics along the Fuchsian locus. By employing this approach, we present a new model of the holomorphic tangent bundle of QF(S) that extends the metric model for Teichm\"uller space defined by Berger and Ebin, and give an integral representation of the Goldman symplectic form and of the holomorphic extension of the Weil-Petersson metric to QF(S), with a new proof of its existence and non-degeneracy. We also determine new bounds for the Schwarzian of Bers projective structures extending Kraus estimate. Lastly, we use this formalism to give alternative proofs to several classic results in quasi-Fuchsian theory

    Methods for the de-identification of electronic health records for genomic research

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    Electronic health records are increasingly being linked to DNA repositories and used as a source of clinical information for genomic research. Privacy legislation in many jurisdictions, and most research ethics boards, require that either personal health information is de-identified or that patient consent or authorization is sought before the data are disclosed for secondary purposes. Here, I discuss how de-identification has been applied in current genomic research projects. Recent metrics and methods that can be used to ensure that the risk of re-identification is low and that disclosures are compliant with privacy legislation and regulations (such as the Health Insurance Portability and Accountability Act Privacy Rule) are reviewed. Although these methods can protect against the known approaches for re-identification, residual risks and specific challenges for genomic research are also discussed

    3-(Adamantan-1-yl)-4-phenyl-1-[(4-phenyl­piperazin-1-yl)meth­yl]-1H-1,2,4-triazole-5(4H)-thione

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    The title mol­ecule, C29H35N5S, displays a chair-shaped piperazine ring, as well as an approximately planar triazole ring (r.m.s. deviation = 0.001 Å) whose phenyl substituent is nearly perpendicular to the mean plane of the five-membered ring [dihedral angle = 88.9 (1)°]. The substituents on the piperazine ring occupy equatorial sites. In the crystal, the adamantyl cage is disordered over two sets of sites with a major component of 67.8 (5)%. Weak inter­molecular C—H⋯S hydrogen bonding is present in the crystal

    3-[(N-Methyl­anilino)meth­yl]-5-(thio­phen-2-yl)-1,3,4-oxadiazole-2(3H)-thione

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    In the title compound, C14H13N3OS2, the thio­phene ring is disordered over two orientations by ca 180° about the C—C bond axis linking the ring to the rest of the mol­ecule, with a site-occupancy ratio of 0.651 (5):0.349 (5). The central 1,3,4-oxadiazole-2(3H)-thione ring forms dihedral angles of 9.2 (5), 4.6 (11) and 47.70 (7)° with the major and minor parts of the disordered thio­phene ring and the terminal phenyl ring, respectively. In the crystal, no significant inter­molecular hydrogen bonds are observed. The crystal packing is stabilized by π–π inter­actions [centroid–centroid distance = 3.589 (2) Å]

    3-(Adamantan-1-yl)-4-ethyl-1H-1,2,4-triazole-5(4H)-thione

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    In the title compound, C14H21N3S, the 1,2,4-triazole ring is nearly planar, with a maximum deviation of 0.003 (4) Å. In the crystal, mol­ecules are linked into inversion dimers by pairs of N—H⋯S hydrogen bonds

    Effect of concrete cover thickness and main reinforcement ratio on flexural behavior of RC beams strengthened by NSM-GFRP bars

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    Experimental and numerical programs were invoked to investigate the effect of concrete cover and area of main steel reinforcement on the flexural behavior of strengthened RC beams by near-surface mounted glass fiber reinforced polymeric (NSM GFRP) bars of different lengths. Nine beams divided into three main groups were tested under four-point bending. The three beams of the first group were strengthened by different lengths of GFRP bars and having a concrete cover of 50 mm, while the three beams in the second group were strengthened in a similar manner as those of the first group but the concrete cover was 30 mm. The main steel reinforcement in the first and second groups was 2Ø10. The three beams of the third group were similar to those of the first and second group but the main steel reinforcement was 2Ø16. The 3-D FE commercial ANSYS program was used for the numerical work. The experimental results showed that decreasing the concrete cover increased the flexural capacity of the strengthened RC beams but this improvement disappeared by decreasing the NSM GFRP bar length. The RC beams flexural strength increased with increasing area of main steel reinforcement. The numerical results showed an agreement with the experimental results

    In Situ Surgery: Is It Safe ? (Experience with 60 cases)

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    Background/Purpose: Neonatal surgical unit (NSU) is the area of a hospital where sick babies having surgical problem go once they are born. Performing in-situ surgery (ISS) in the NSU is relatively a new concept that is gaining popularity in the last decade. Critically ill neonates who are too ill to transfer to the operating room can undergo safe surgery in the NSU environment of a fully-equipped pediatric hospital. Transfer of the critically ill neonates is time consuming, utilizing manpower and requiring suitable portable ventilators and extensive monitoring equipments. Materials & Methods: This is a prospective study conducted on 60 neonates admitted in the surgical neonatal unit of the Cairo University pediatric hospital (Abou-Elrish) and where subjected to surgical procedures in the unit itself. The patients were categorized into 3 groups: The First group was the group at the beginning of the study for which minor procedures were selected. The second group was those neonates that were operated upon on emergency base for which transfer could be hazardous. The last group included those patients on high settings of ventilation and critically ill neonates with extensive monitoring. Results: There was no mortality in the study related to the procedures itself. Group I patients: the time of the surgical procedures was longer than that in the OR and no increase in the infection rate was noticed. Group II in which emergency procedures were carried on showed also increase in operating time but better perioperative circumstances regarding secondary insult to viable structures & less infection rate. Group III: no significant change in outcome in comparison to cases transferred to OR except that the perioperative circumstances were better for the surgeon, anesthesiiologist & nursing teams. Conclusion: NSU is a safe place for performing in-situ surgery (ISS) without increased risk of infection. Successful operative intervention within NSU requires good planning and cooperation between anesthesiologist, surgeons, neonatologist and nursing staff. Maximum benefit is observed in neonates who have definite risk attached to transfer to operating room. Index Word: In-Situ Surgery (ISS) – Neonatal Surgical Unit (NSU)
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