Mono-sensitisation to peanut component Ara h 6: a case series of five children and literature review

Here, we summarise the current clinical knowledge on Ara h 6 sensitisation and clinical relevance of this sensitisation pattern using five illustrative clinical cases. The literature search yielded a total of 166 papers, and an additional relevant article was found by ‘snowballing’. A total of ten articles were considered relevant for this review. Most studies included patients with a sensitisation to Ara h 6 and cosensitisation to Ara h 2. Only three studies showed patients with a mono-sensitisation to Ara h 6. This illustrates that Ara h 6 mono-sensitisation has been neglected in literature. We present a case series of five children with sensitisation to peanut component Ara h 6. Only one of these five patients showed Ara h 8 cosensitivity. Three out of the five children had a positive double-blind placebo-controlled food challenge (DBPCFC), with moderate to strong reactions. Conclusion: A mono-sensitisation to peanut component Ara h 6 is uncommon but can cause severe allergic reactions. Therefore, the determination of sIgE to Ara h 6 is warranted in patients with a suspected peanut allergy, especially in the absence of sensitisation to Ara h 1, 2, 3 and 9.(Table presented.

Meeting of the Ecosystem Approach Correspondence Group on on Pollution Monitoring (CorMon Pollution)

In accordance with the UNEP/MAP Programme of Work adopted by COP 21 for the biennium 2020-2021, the United Nations Environment Programme/Mediterranean Action Plan-Barcelona Convention Secretariat (UNEP/MAP) and its Programme for the Assessment and Control of Marine Pollution in the Mediterranean (MED POL) organized the Meeting of the Ecosystem Approach Correspondence Group on Pollution Monitoring (CorMon on Pollution Monitoring). The Meeting was held via videoconference on 26-27 April 2021. 2. The main objectives of the Meeting were to: a) Review the Monitoring Guidelines/Protocols for IMAP Common Indicator 18, as well as the Monitoring Guidelines/Protocols for Analytical Quality Assurance and Reporting of Monitoring Data for IMAP Common Indicators 13, 14, 17, 18 and 20; b) Take stock of the state of play of inter-laboratory testing and good laboratory practice related to IMAP Ecological Objectives 5 and 9; c) Analyze the proposal for the integration and aggregation rules for IMAP Ecological Objectives 5, 9 and 10 and assessment criteria for contaminants and nutrients; d) Recommend the ways and means to strengthen implementation of IMAP Pollution Cluster towards preparation of the 2023 MED Quality Status Report

Spatial and Temporal Variations of the Water Quality of the Tiflet River, Province of Khemisset, Morocco

Humanity’s water needs are constantly increasing, however, under the action of humanity themselves, the reserves of this substance are, constantly, deteriorating in quantity and quality. It is, therefore, necessary to preserve the water reserves. However, any development of a hydrosystem’s quality conservation strategy is based on determining the chemical characteristics of its waters. Therefore, the objective of this study is to investigate the spatial and temporal variations of water quality in the Tiflet River, a watercourse in the northwest of Morocco, to estimate its degree of pollution and to determine its main sources of pollution. Thus, eight stations, distributed along the watercourse and positioned taking into account the potential sources of pollution, were fixed, and eleven physicochemical parameters were, seasonally, evaluated. Multivariate statistical techniques were used to assess variations in water quality and identify the main factors responsible for pollution. The results showed that wastewater discharges into the river can increase the water salinity, phosphorus load and organic pollution load of the river. The total loads of nitrogen and nitrate pollution were higher compared to the standard norms in the stations exposed to agricultural pollution and to the leaching of the watersheds, which could aggravate the eutrophication state of the river and stimulate the growth of aquatic vegetation. The organic pollution load recorded in the wet season is low, compared to that recorded in the dry season. Whereas, the nutrient load recorded during the dry season is low, compared to that recorded in the wet season. An overall pollution index was used, classifying surface waters from sub-clean to moderately polluted

Erratum to: Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (Autophagy, 12, 1, 1-222, 10.1080/15548627.2015.1100356

No abstract available