532 research outputs found
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Childhood chronic physical illness and adult emotional health: a systematic review and meta-analysis
Background: Childhood chronic physical illness is associated with a greater vulnerability for emotional problems (i.e., depression and anxiety) in childhood. However, little is known about life-long effects of childhood chronic physical illness on mental health. The present study aims to systematically review evidence for associations between eight chronic physical illnesses with childhood onset (arthritis, asthma, cancer, chronic renal failure, congenital heart disease, cystic fibrosis, type 1 diabetes, and epilepsy) and adult emotional problems.
Methods: A database search of MEDLINE, PsycARTICLES, PsycINFO, and ScienceDirect was undertaken, and random effects meta-analyses were used to synthesize evidence from eligible studies.
Results: In total, 37 studies were eligible for the systematic review (n = 45,733) and of these, 34 studies were included into the meta-analyses (n = 45,358). There were overall associations between childhood chronic physical illness and adult depression (OR = 1.31; 95% CI [1.12, 1.54]) and anxiety (OR = 1.47; 95% CI [1.13, 1.92]). Separate meta-analyses for childhood asthma, type 1 diabetes and cancer were also conducted, with cancer being significantly associated with adult depression (OR = 1.19; 95% CI [1.00, 1.42]).
Conclusions: The effects of childhood chronic physical illness on the risk of emotional problems persist beyond childhood and adolescence. Mental health prevention and intervention strategies targeting children with chronic physical illnesses can have long-term benefits
Normal zone in -coated conductors
We consider the distribution of an electric field in YBCO-coated conductors
for a situation in which the DC transport current is forced into the copper
stabilizer due to a weak link -- a section of the superconducting film with a
critical current less than the transport current. The electric field in the
metal substrate is also discussed. The results are compared with recent
experiments on normal zone propagation in coated conductors for which the
substrate and stabilizer are insulated from each other. The potential
difference between the substrate and stabilizer, and the electric field in the
substrate outside the normal zone can be accounted for by a large screening
length in the substrate, comparable to the length of the sample. During a
quench, the electric field inside the interface between YBCO and stabilizer, as
well as in the buffer layer, can be several orders of magnitude greater than
the longitudinal macroscopic electric field inside the normal zone. We
speculate on the possibility of using possible microscopic electric discharges
caused by this large (kV/cm) electric field as a means to detect a
quench.Comment: 8 pages, 4 figure
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3D printed ventricular septal defect patch: a primer for the 2015 Radiological Society of North America (RSNA) hands-on course in 3D printing.
Hand-held three dimensional models of the human anatomy and pathology, tailored-made protheses, and custom-designed implants can be derived from imaging modalities, most commonly Computed Tomography (CT). However, standard DICOM format images cannot be 3D printed; instead, additional image post-processing is required to transform the anatomy of interest into Standard Tessellation Language (STL) format is needed. This conversion, and the subsequent 3D printing of the STL file, requires a series of steps. Initial post-processing involves the segmentation-demarcation of the desired for 3D printing parts and creating of an initial STL file. Then, Computer Aided Design (CAD) software is used, particularly for wrapping, smoothing and trimming. Devices and implants that can also be 3D printed, can be designed using this software environment. The purpose of this article is to provide a tutorial on 3D Printing with the test case of complex congenital heart disease (CHD). While the infant was born with double outlet right ventricle (DORV), this hands-on guide to be featured at the 2015 annual meeting of the Radiological Society of North America Hands-on Course in 3D Printing focused on the additional finding of a ventricular septal defect (VSD). The process of segmenting the heart chambers and the great vessels will be followed by optimization of the model using CAD software. A virtual patch that accurately matches the patient's VSD will be designed and both models will be prepared for 3D printing
Crystal Structure Search with Random Relaxations Using Graph Networks
Materials design enables technologies critical to humanity, including
combating climate change with solar cells and batteries. Many properties of a
material are determined by its atomic crystal structure. However, prediction of
the atomic crystal structure for a given material's chemical formula is a
long-standing grand challenge that remains a barrier in materials design. We
investigate a data-driven approach to accelerating ab initio random structure
search (AIRSS), a state-of-the-art method for crystal structure search. We
build a novel dataset of random structure relaxations of Li-Si battery anode
materials using high-throughput density functional theory calculations. We
train graph neural networks to simulate relaxations of random structures. Our
model is able to find an experimentally verified structure of Li15Si4 it was
not trained on, and has potential for orders of magnitude speedup over AIRSS
when searching large unit cells and searching over multiple chemical
stoichiometries. Surprisingly, we find that data augmentation of adding
Gaussian noise improves both the accuracy and out of domain generalization of
our models.Comment: Removed citations from the abstract, paper content is unchange
The effects of superconductor-stabilizer interfacial resistance on quench of current-carrying coated conductor
We present the results of numerical analysis of a model of normal zone
propagation in coated conductors. The main emphasis is on the effects of
increased contact resistance between the superconducting film and the
stabilizer on the speed of normal zone propagation, the maximum temperature
rise inside the normal zone, and the stability margins. We show that with
increasing contact resistance the speed of normal zone propagation increases,
the maximum temperature inside the normal zone decreases, and stability margins
shrink. This may have an overall beneficial effect on quench protection quality
of coated conductors. We also briefly discuss the propagation of solitons and
development of the temperature modulation along the wire.Comment: To be published in Superconductor Science and Technology. This
preprint contains one animated figure (Fig. 6(a)). when asked whether you
want to play the content, click "Play". Acrobat Reader (Windows and Mac, but
not Linux) will play embedded flash movies. In the printed copy Fig. 6(b)
will show the temperature profile at gamma t=15
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