The Moonlight Trail

With Ukulele arrangement. Contains advertisements and/or short musical examples of pieces being sold by publisher.https://digitalcommons.library.umaine.edu/mmb-vp/7004/thumbnail.jp

Constrained flow around a magnetic obstacle

Many practical applications exploit an external local magnetic field -- magnetic obstacle -- as an essential part of their constructions. Recently, it has been demonstrated that the flow of an electrically conducting fluid influenced by an external field can show several kinds of recirculation. The present paper reports a 3D numerical study whose some results are compared with an experiment about such a flow in a rectangular duct.Comment: accepted to JFM, 26 pages, 14 figure

Corpus Linguistics and the Original Public Meaning of the Sixteenth Amendment

Moore v. United States raises the question whether unrealized gains, such as an increase in property value or a stock portfolio, constitute “incomes, from whatever source derived” under the original meaning of the Sixteenth Amendment. Moore is widely viewed as the most important tax case to reach the United States Supreme Court in decades. It is also an opportunity for the Court to refine its theory and method of finding original meaning. We focus here on the original public meaning of the Sixteenth Amendment—the ordinary, common meaning attributed to its text by the general public in 1913. So far, the parties and amici have relied on contemporaneous dictionaries to argue over such meaning. But the cited dictionaries do not establish the ordinary meaning of “incomes, from whatever source derived”; instead, they highlight a key ambiguity in the very terms of the definitions presented. This article fills important gaps in the original public meaning analysis in Moore. More broadly, it also charts a path for refining the theory and methodology of the originalist inquiry more generally. At the theoretical level, it introduces principles of the philosophy of language and theoretical linguistics that align with—and help refine—strands of the Court’s originalist inquiry. And as to method, it introduces evidence from corpus linguistic analysis to provide a transparent, replicable basis for assessing the ordinary public meaning of the Sixteenth Amendment’s relevant terms. We use the Corpus of Historical American English (“COHA”) to analyze the ordinary public meaning of the constitutional language at the time of ratification of the Sixteenth Amendment. At the “words-to-meaning” level, we show that “income(s)” was always used in 1900-1912 to refer to realized gains. We also perform a “meaning-to-words” analysis, showing that unrealized gains were always referred to using terms other than “income(s).” Our corpus linguistic analysis reveals that the original public meaning of “incomes, from whatever source derived” almost certainly only covers realized gains. And it charts a path for greater transparency, objectivity, and replicability than more traditional tools of originalism

Metal ion responsive adhesion of vesicles by conformational switching of a non-covalent linker

This contribution describes the metal ion responsive adhesion of vesicles induced by a conformational switch of a non-covalent linker molecule. A p-tert-butylbenzyl dimer with a flexible N,N'-bis(3-aminopropyl)ethylenediamine spacer was used as a non-covalent linker, which induces aggregation and adhesion (but not fusion) of host bilayer vesicles composed of amphiphilic beta-cyclodextrins by the formation of hydrophobic inclusion complexes. The aggregation and adhesion of the vesicles in dilute aqueous solution was confirmed by isothermal titration calorimetry (ITC), optical density measurements at 600 nm (OD600), dynamic light scattering (DLS), zeta-potential measurements, cryogenic transmission electron microscopy (cryo-TEM) and fluorescence spectroscopy. However, in the presence of a divalent metal ion like Cu(2+), the tetra-amine linker molecule forms a stable metal coordination complex and dramatically switches its conformation from linear to bent, which results in the dissociation of intervesicular complexes, and leads to the dispersion of vesicle clusters. This process is reversible in the presence of a strong metal ion chelator, such as EDTA, that scavenges the Cu(2+) ion complexed by the linker. The linker molecule regains its linear conformation and triggers the reaggregation of the vesicles. In contrast, conformational switching was inhibited by introducing a rigid N,N'-bis(3-aminopropyl)piperazine spacer in the non-covalent linker molecule and vesicles do not aggregate in the presence of a cyclic guest that can only bind intravesicularly. Thus, a metal ion regulated molecular switch can control the aggregation state of an organic colloidal solution.</p

Behavioral metabolution: the adaptive and evolutionary potential of metabolism-based chemotaxis

We use a minimal model of metabolism-based chemotaxis to show how a coupling between metabolism and behavior can affect evolutionary dynamics in a process we refer to as behavioral metabolution. This mutual influence can function as an in-the-moment, intrinsic evaluation of the adaptive value of a novel situation, such as an encounter with a compound that activates new metabolic pathways. Our model demonstrates how changes to metabolic pathways can lead to improvement of behavioral strategies, and conversely, how behavior can contribute to the exploration and fixation of new metabolic pathways. These examples indicate the potentially important role that the interplay between behavior and metabolism could have played in shaping adaptive evolution in early life and protolife. We argue that the processes illustrated by these models can be interpreted as an unorthodox instantiation of the principles of evolution by random variation and selective retention. We then discuss how the interaction between metabolism and behavior can facilitate evolution through (i) increasing exposure to environmental variation, (ii) making more likely the fixation of some beneficial metabolic pathways, (iii) providing a mechanism for in-the-moment adaptation to changes in the environment and to changes in the organization of the organism itself, and (iv) generating conditions that are conducive to speciatio

The results of using a tendon autograft as a new rotator cable for patients with a massive rotator cuff tear:a technical note and comparative outcome analysis

Background: Several surgical reconstructive options are available to treat massive rotator cuff tears (MRCTs). The rotator cable has an important function and we evaluated the clinical result after arthroscopic reconstruction of the rotator cable with an autograft tendon. Methods: A prospective pilot study was performed with inclusion of four patients, average age of 64 years, with an irreparable MRCT. The patients underwent an arthroscopic reconstruction of the rotator cable with the use of the long head of biceps tendon autograft, except for one which was reconstructed with a hamstring tendon. Pre- and postsurgically, the Constant-Murley Score (CMS), Western Ontario Rotator Cuff Index (WORC), Simple Shoulder Test (SST), visual analog scale (VAS) scores, and an MRI was performed. Clinical results of the study group were compared with clinical results of comparable cohort of patients with a MRCT, treated non-operatively with physiotherapy. Results: The CMS score increased after surgery in three of the four patients. The improvement of CMS score was comparable to the improvement of the CMS score encountered in a comparable cohort. The MRI at 12 months follow-up showed that the reconstructed rotator cable was disintegrated in all patients and the rotator cuff was detached and retracted. Conclusions: In our pilot study, arthroscopic reconstruction of the rotator cable using a tendon autograft failed over time and showed no clinical benefit in comparison to the non-operative treatment with physiotherapy. Trial registration: The regional Medical Ethical Committee (Zwolle) gave approval at 14th of October 2016 and assigned no. 16.06100