Can Magic Mushrooms Remove Inherited Trauma?

This presentation is about a proposal wherein mice are exposed to psilocybin over multiple generations to study the effects of psilocybin on fear response, hippocampal growth and gene expression

Beneficial effects of childhood selective dorsal rhizotomy in adulthood

Background: Selective dorsal rhizotomy (SDR) has been used to treat children with spastic cerebral palsy (CP) for over three decades. However, little is known about the outcomes of childhood SDR in adults.  Objectives: 1) To study the effects of childhood SDR on the quality of life and ambulatory function in adult life. 2) To determine late side effects of SDR in adults.   Methods: Adults (> 17.9 years) who underwent SDR in childhood (2 - 17.9 years) between 1987 and 2013 were surveyed in 2015. Patients completed a survey, including questions on demographic information, quality of life, health, surgical outcomes, motor function, manual ability, pain, braces/orthotics, post-SDR treatment, living situation, education level, work status, and side effects of SDR.  Results: In our study population of 294 patients (18.0 - 37.4 years), patients received SDR during the ages of 2.0 - 17.9 years and were followed up 2.2 to 28.3 years after surgery. Eighty-four percent had spastic diplegia, 12% had spastic quadriplegia, and 4% had spastic triplegia. The majority (88%) of patients reported improved post-SDR quality of life and 1% considered the surgery detrimental. Most (83%) would recommend the procedure to others and 3% would not. However, patients who would not recommend SDR to others ambulated with a walker or were not ambulatory at all prior to SDR. The majority (83%) of patients improved (30%) or remained stable (53%) in ambulation. Twenty-nine percent of patients reported pain, mostly in the back and lower limbs, with a mean pain level of 4.4 ± 2.4 on the Numeric Pain Rating Scale (NPRS). Decreased sensation in small areas of the lower limbs was reported by 8% of patients, though this did not affect daily life. Scoliosis was diagnosed in 28%, with 40% of these patients pursuing treatment. Whether scoliosis was related to SDR is not clear, though scoliosis is known to occur in patients with CP and also in the general population. Only 4% of patients underwent spinal fusion.  Orthopedic surgeries were pursued by 59% of patients. The most common orthopedic surgeries were hamstring lengthenings (31%), Achilles tendon lengthenings (18%), adductor lengthenings (16%), and derotational osteotomies (16%). Twenty-four percent of all patients later underwent hip surgery and 8% had surgeries on their knees.  Conclusion: Results of this study indicate that the beneficial effects of childhood SDR extend to adulthood quality of life and ambulatory function without late side effects of surgery

SOF’S ROLE IN STRATEGIC COMPETITION: A WARGAME

Includes Supplementary MaterialCan a wargame effectively model how Special Operation Forces’ (SOF) irregular warfare capabilities influence strategic competition, and more broadly, do wargames have a place in the education of SOF professionals? SOF needs educational tools that stimulate critical thinking and intellectual creativity to address the challenges and complexities of irregular warfare and strategic competition so they can maintain their position as the DOD’s premier option for irregular warfare. Educational wargames have an extensive history in professional military organizations, and the wargame Tears of Tyranny is ready for use now to educate joint SOF on irregular warfare at the tactical and operational levels. Further development of Tears of Tyranny should include digitization and refinement through an additional capstone team.Outstanding ThesisMajor, United States ArmyMajor, United States ArmyMajor, United States ArmyMajor, United States ArmyApproved for public release. Distribution is unlimited

Concert recording 2016-04-16

[Track 01]. Meditation no. 1 / Casey Cangelosi -- [Track 02]. Into the air / Ivan Trevino -- [Track 03]. Ku-ka ilimoku / Christopher Rouse -- [Track 04]. Good vibes / Oscar Hernandez -- [Track 05]. Arabesque no. 2 / Claude Debussy ; arranged by Evans -- [Track 06]. The odyssey, according to Penelope. Afternoon at the park ; [Track 07]. Toddling waltz ; [Track 08]. Babble songs ; [Track 09]. Naptime prelude ; [Track 10]. Run amok rondo / Kevin Bobo -- [Track 11]. Tiger dance / Jeffery Dennis Smith

2018 Voice Honors Recital

KSU School of Music presents the 2018 Voice Honors Recital.https://digitalcommons.kennesaw.edu/musicprograms/2023/thumbnail.jp

Post Occupancy Evaluation of School Refurbishment Projects: Multiple Case Study in the UK

Buildings inevitably deteriorate with time. Schools buildings are no exception and require refurbishment at times. Despite the UK Government announcing the £1 billion funding for rebuilding 50 schools over 10 years starting 2010–2021, it is common practice for builders and designers to, upon completion of a building project, move on to the next development without considering how the completed building performs. This research undertakes a post occupancy evaluation (POE) of three schools in the West Midlands, UK with specific focus on building services, viz., heating, lighting, and air conditioning and ventilation. The research adopted a mixed philosophical approach of interpretivism and post-positivism to conduct inductive reasoning. A questionnaire that collected both quantitative and qualitative primary data was distributed to the end-users of the schools. Data was analysed using the Cronbach’s alpha, one sample t-test and Kruskal–Wallis test to identify any differences between the questionnaire responses. Findings revealed that building users demanded greater control of the internal environment thus contradicting the current trend for automated ‘intelligent systems’ approaches. This research represents the first work to consider the contractor’s perspective towards developing a better understanding of client satisfaction with the school buildings. Moreover, the POE result represents a notable pragmatic advancement to knowledge that will influence the contractor’s knowledge and understanding of client satisfaction, and where to improve upon these

2018 Advent Devotional

2018 Advent Devotions written by the students of Concordia Seminary, St. Louishttps://scholar.csl.edu/osp/1014/thumbnail.jp