2 research outputs found
Ultrastructural Observations on the Effect of 4-Hydroxyanisole on Normal Human Melanocytes in Tissue Culture
- Author
- Publication venue
- 'Wiley'
- Publication date
- Field of study
Integrative pathway enrichment analysis of multivariate omics data
- Author
- Aaltonen Lauri A.
- Abascal Federico
- Abascal Federico
- Abd-Rabbo Diala
- Abeshouse Adam
- Aburatani Hiroyuki
- Adams David J.
- Agrawal Nishant
- Ahn Keun Soo
- Ahn Sung-Min
- Aikata Hiroshi
- Akbani Rehan
- Akdemir Kadir C.
- Al-Ahmadie Hikmat
- Al-Sedairy Sultan T.
- Al-Shahrour Fatima
- Alawi Malik
- Albert Monique
- Aldape Kenneth
- Alexandrov Ludmil B.
- Ally Adrian
- Alsop Kathryn
- Alvarez Eva G.
- Amary Fernanda
- Amin Samirkumar B.
- Amin Samirkumar B.
- Aminou Brice
- Ammerpohl Ole
- Anderson Matthew J.
- Ang Yeng
- Antonello Davide
- Anur Pavana
- Aparicio Samuel
- Appelbaum Elizabeth L.
- Arai Yasuhito
- Aretz Axel
- Arihiro Koji
- Ariizumi Shun-ichi
- Armenia Joshua
- Arnau Gisela Mir
- Arnould Laurent
- Asa Sylvia
- Assenov Yassen
- Atwal Gurnit
- Aukema Sietse
- Auman J. Todd
- Aure Miriam R. R.
- Awadalla Philip
- Aymerich Marta
- Bader Gary D.
- Bader Gary D.
- Baez-Ortega Adrian
- Bailey Matthew H.
- Bailey Peter J.
- Balasundaram Miruna
- Balu Saianand
- Bandopadhayay Pratiti
- Banks Rosamonde E.
- Barbi Stefano
- Barbour Andrew P.
- Barenboim Jonathan
- Barenboim Jonathan
- Barnholtz-Sloan Jill
- Barr Hugh
- Barrera Elisabet
- Bartlett John
- Bartolome Javier
- Bassi Claudio
- Bathe Oliver F.
- Baumhoer Daniel
- Bavi Prashant
- Baylin Stephen B.
- Bazant Wojciech
- Beardsmore Duncan
- Beck Timothy A.
- Behjati Sam
- Behren Andreas
- Bell Cindy
- Beltran Sergi
- Benz Christopher
- Berchuck Andrew
- Bergmann Anke K.
- Bergstrom Erik N.
- Berman Benjamin P.
- Berney Daniel M.
- Bernhart Stephan H.
- Beroukhim Rameen
- Beroukhim Rameen
- Berrios Mario
- Bersani Samantha
- Bertl Johanna
- Bertl Johanna
- Betancourt Miguel
- Bhandari Vinayak
- Bhosle Shriram G.
- Biankin Andrew V.
- Bieg Matthias
- Bigner Darell
- Binder Hans
- Birney Ewan
- Birrer Michael
- Biswas Nidhan K.
- Bjerkehagen Bodil
- Bodenheimer Tom
- Boice Lori
- Bonizzato Giada
- Boot Arnoud
- Bootwalla Moiz S.
- Borg Ake
- Borkhardt Arndt
- Boroevich Keith A.
- Boroevich Keith A.
- Borozan Ivan
- Borst Christoph
- Bosenberg Marcus
- Bosio Mattia
- Boultwood Jacqueline
- Bourque Guillaume
- Boutros Paul C.
- Boutros Paul C.
- Bova G. Steven
- Bowen David T.
- Bowlby Reanne
- Bowtell David D. L.
- Boyault Sandrine
- Boyce Rich
- Boyd Jeffrey
- Brazma Alvis
- Brennan Paul
- Brewer Daniel S.
- Brinkman Arie B.
- Bristow Robert G.
- Broaddus Russell R.
- Brock Jane E.
- Brock Malcolm
- Broeks Annegien
- Brooks Angela N.
- Brooks Denise
- Brors Benedikt
- Brunak Søren
- Brunak Søren
- Bruxner Timothy J. C.
- Bruzos Alicia L.
- Buchanan Alex
- Buchhalter Ivo
- Buchholz Christiane
- Bullman Susan
- Burke Hazel
- Burkhardt Birgit
- Burns Kathleen H.
- Busanovich John
- Bustamante Carlos D.
- Butler Adam P.
- Butte Atul J.
- Byrne Niall J.
- Børresen-Dale Anne-Lise
- Caesar-Johnson Samantha J.
- Cafferkey Andy
- Cahill Declan
- Calabrese Claudia
- Caldas Carlos
- Calvo Fabien
- Camacho Niedzica
- Campbell Peter J.
- Campbell Peter J.
- Campo Elias
- Cantù Cinzia
- Cao Shaolong
- Carey Thomas E.
- Carlevaro-Fita Joana
- Carlevaro-Fita Joana
- Carlsen Rebecca
- Cataldo Ivana
- Cazzola Mario
- Cebon Jonathan
- Cerfolio Robert
- Chadwick Dianne E.
- Chakravarty Dimple
- Chakravarty Dimple
- Chalmers Don
- Chan Calvin Wing Yiu
- Chan Calvin Wing Yiu
- Chan Kin
- Chan-Seng-Yue Michelle
- Chandan Vishal S.
- Chang David K.
- Chanock Stephen J.
- Chantrill Lorraine A.
- Chateigner Aurélien
- Chatterjee Nilanjan
- Chayama Kazuaki
- Chen Hsiao-Wei
- Chen Jieming
- Chen Ken
- Chen Ken
- Chen Yiwen
- Chen Zhaohong
- Cherniack Andrew D.
- Chien Jeremy
- Chiew Yoke-Eng
- Chin Suet-Feung
- Cho Juok
- Cho Sunghoon
- Choi Jung Kyoon
- Choi Jung Kyoon
- Choi Wan
- Chomienne Christine
- Chong Zechen
- Choo Su Pin
- Chou Angela
- Christ Angelika N.
- Christie Elizabeth L.
- Chuah Eric
- Cibulskis Carrie
- Cibulskis Kristian
- Cingarlini Sara
- Clapham Peter
- Claviez Alexander
- Cleary Sean
- Cloonan Nicole
- Cmero Marek
- Collins Colin C.
- Connor Ashton A.
- Cooke Susanna L.
- Cooper Colin S.
- Cope Leslie
- Corbo Vincenzo
- Cordes Matthew G.
- Cordner Stephen M.
- Cortés-Ciriano Isidro
- Covington Kyle
- Cowin Prue A.
- Craft Brian
- Craft David
- Creighton Chad J.
- Cun Yupeng
- Curley Erin
- Cutcutache Ioana
- Czajka Karolina
- Czerniak Bogdan
- Dagg Rebecca A.
- Danilova Ludmila
- Davi Maria Vittoria
- Davidson Natalie R.
- Davies Helen
- Davis Ian J.
- Davis-Dusenbery Brandi N.
- Dawson Kevin J.
- De Bono Johann S.
- De La Vega Francisco M.
- De Paoli-Iseppi Ricardo
- deFazio Anna
- Defreitas Timothy
- Delaneau Olivier
- Demchok John A.
- Demeulemeester Jonas
- Demidov German M.
- Demircioğlu Deniz
- Dennis Nening M.
- Denroche Robert E.
- Dentro Stefan C.
- Desai Nikita
- Deshpande Vikram
- Deshwar Amit G.
- Desmedt Christine
- Deu-Pons Jordi
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- Dhalla Noreen
- Dhani Neesha C.
- Dhingra Priyanka
- Dhingra Priyanka
- Dhir Rajiv
- Diamanti Klev
- Diamanti Klev
- DiBiase Anthony
- Ding Li
- Ding Shuai
- Dinh Huy Q.
- Dirix Luc
- Doddapaneni HarshaVardhan
- Donmez Nilgun
- Dow Michelle T.
- Drapkin Ronny
- Drechsel Oliver
- Drews Ruben M.
- Dudderidge Tim
- Dueso-Barroso Ana
- Dunford Andrew J.
- Dunn Michael
- Dursi Lewis Jonathan
- Duthie Fraser R.
- Dutton-Regester Ken
- Eagles Jenna
- Easton Douglas F.
- Edmonds Stuart
- Edwards Paul A.
- Edwards Sandra E.
- Eeles Rosalind A.
- Ehinger Anna
- Eils Juergen
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- El-Naggar Adel
- Eldridge Matthew
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- Escaramis Georgia
- Espiritu Shadrielle M. G.
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- Eyfjord Jorunn E.
- Faltas Bishoy M.
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- Ferguson Martin L.
- Ferretti Vincent
- Feuerbach Lars
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- Field Matthew A.
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- Fisher Cyril
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- Fleshner Neil E.
- Flicek Paul
- Foekens John A.
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- Fonseca Nuno A.
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- Foster Christopher S.
- Fox Natalie S.
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- Fraser Michael
- Frazer Scott
- Frenkel-Morgenstern Milana
- Friedman William
- Frigola Joan
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- Fujimoto Akihiro
- Fujita Masashi
- Fukayama Masashi
- Fulton Lucinda A.
- Fulton Robert S.
- Furuta Mayuko
- Futreal P. Andrew
- Füllgrabe Anja
- Gabriel Stacey B.
- Gallinger Steven
- Gambacorti-Passerini Carlo
- Gambacorti-Passerini Carlo
- Gao Jianjiong
- Gao Shengjie
- Garraway Levi
- Garred Øystein
- Garrison Erik
- Garsed Dale W.
- Garsed Dale W.
- Gehlenborg Nils
- Gelpi Josep L. L.
- George Joshy
- Gerhard Daniela S.
- Gerhauser Clarissa
- Gershenwald Jeffrey E.
- Gerstein Mark
- Gerstein Mark
- Gerstung Moritz
- Getz Gad
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- Gibson Bob
- Gill Anthony J.
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- Glodzik Dominik
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- Gonzalez-Perez Abel
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- Gordenin Dmitry A.
- Gossage James
- Gotoh Kunihito
- Govindan Ramaswamy
- Göke Jonathan
- Grabau Dorthe
- Graham Janet S.
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- Greger Liliana
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- Grossman Robert L.
- Grundhoff Adam
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- Guo Qianyun
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- Gupta Manaswi
- Gupta Shailja
- Gut Ivo G.
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- Gut Marta
- Ha Gavin
- Haake Andrea
- Haan David
- Haan David
- Haas Siegfried
- Haase Kerstin
- Haber James E.
- Habermann Nina
- Hach Faraz
- Haider Syed
- Hama Natsuko
- Hamdy Freddie C.
- Hamilton Anne
- Hamilton Mark P.
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- Han Leng
- Hanna George B.
- Hansmann Martin
- Haradhvala Nicholas J.
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- Harismendy Olivier
- Harliwong Ivon
- Harmanci Arif O.
- Harmanci Arif O.
- Harrington Eoghan
- Hasegawa Takanori
- Haussler David
- Hawkins Steve
- Hayami Shinya
- Hayashi Shuto
- Hayes D. Neil
- Hayes Stephen J.
- Hayward Nicholas K.
- Hazell Steven
- He Yao
- Heath Allison P.
- Heath Simon C.
- Hedley David
- Hegde Apurva M.
- Heiman David I.
- Heinold Michael C.
- Heins Zachary
- Heisler Lawrence E.
- Hellstrom-Lindberg Eva
- Helmy Mohamed
- Helmy Mohamed
- Heo Seong Gu
- Hepperla Austin J.
- Heredia-Genestar José María
- Herrmann Carl
- Herrmann Carl
- Hersey Peter
- Hess Julian M.
- Hess Julian M.
- Hilmarsdottir Holmfridur
- Hinton Jonathan
- Hirano Satoshi
- Hiraoka Nobuyoshi
- Hoadley Katherine A.
- Hobolth Asger
- Hobolth Asger
- Hodzic Ermin
- Hodzic Ermin
- Hoell Jessica I.
- Hoffmann Steve
- Hofmann Oliver
- Holbrook Andrea
- Holik Aliaksei Z.
- Hollingsworth Michael A.
- Holmes Oliver
- Holt Robert A.
- Hong Chen
- Hong Chen
- Hong Eun Pyo
- Hong Jongwhi H.
- Hooijer Gerrit K.
- Hornshøj Henrik
- Hornshøj Henrik
- Hosoda Fumie
- Hou Yong
- Hovestadt Volker
- Howat William
- Hoyle Alan P.
- Hruban Ralph H.
- Hu Jianhong
- Hu Taobo
- Hua Xing
- Huang Kuan-lin
- Huang Mei
- Huang Mi Ni
- Huang Vincent
- Huang Yi
- Huber Wolfgang
- Hudson Thomas J.
- Hummel Michael
- Hung Jillian A.
- Huntsman David
- Hupp Ted R.
- Huse Jason
- Huska Matthew R.
- Hutter Barbara
- Hutter Carolyn M.
- Hübschmann Daniel
- Iacobuzio-Donahue Christine A.
- Imbusch Charles David
- Imielinski Marcin
- Imoto Seiya
- Isaacs William B.
- Isaev Keren
- Isaev Keren
- Ishikawa Shumpei
- Iskar Murat
- Islam S. M. Ashiqul
- Ittmann Michael
- Ivkovic Sinisa
- Izarzugaza Jose M. G.
- Izarzugaza Jose M. G.
- Jacquemier Jocelyne
- Jakrot Valerie
- Jamieson Nigel B.
- Jan Komorowski null
- Jang Gun Ho
- Jang Se Jin
- Jayaseelan Joy C.
- Jayasinghe Reyka
- Jäger Natalie
- Jefferys Stuart R.
- Jegalian Karine
- Jennings Jennifer L.
- Jeon Seung-Hyup
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- Jolly Clemency
- Joly Yann
- Jonasson Jon G.
- Jones Corbin D.
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- Jung Jongsun
- Juul Malene
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- Kabbe Rolf
- Kahles Andre
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- Kahraman Abdullah
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- Kaiser Vera B.
- Kakavand Hojabr
- Kalimuthu Sangeetha
- Kang Koo Jeong
- Karaszi Katalin
- Karlan Beth
- Karlić Rosa
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- Kassahn Karin S.
- Katai Hitoshi
- Kato Mamoru
- Katoh Hiroto
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- Kleinheinz Kortine
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- Komura Daisuke
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- Kong Gu
- Kool Marcel
- Korbel Jan O.
- Korbel Jan O.
- Korchina Viktoriya
- Korshunov Andrey
- Koscher Michael
- Koster Roelof
- Kote-Jarai Zsofia
- Koures Antonios
- Kovacevic Milena
- Kremeyer Barbara
- Kretzmer Helene
- Kreuz Markus
- Krishnamurthy Savitri
- Kube Dieter
- Kumar Kiran
- Kumar Pardeep
- Kumar Sushant
- Kumar Sushant
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- Kübler Kirsten
- Küppers Ralf
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- Lai Phillip H.
- Laird Peter W.
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- Lalonde Emilie
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- Lander Eric
- Landgraf Pablo
- Landoni Luca
- Langerød Anita
- Lanzós Andrés
- Lanzós Andrés
- Larsimont Denis
- Larsson Erik
- Lathrop Mark
- Lau Loretta M. S.
- Lawerenz Chris
- Lawlor Rita T.
- Lawrence Michael S.
- Lawrence Michael S.
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- Lazic Ana Mijalkovic
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- Lee Darlene
- Lee Donghoon
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- Lee Eunjung Alice
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- Lee Jake June-Koo
- Lee Jeong-Yeon
- Lee Juhee
- Lee Ming Ta Michael
- Lee-Six Henry
- Lehmann Kjong-Van
- Lehmann Kjong-Van
- Lehrach Hans
- Lenze Dido
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- Leongamornlert Daniel A.
- Leshchiner Ignaty
- Letourneau Louis
- Letunic Ivica
- Levine Douglas A.
- Lewis Lora
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- Li Chang
- Li Constance H.
- Li Haiyan Irene
- Li Jun
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- Li Xiaobo
- Li Xiaotong
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- Li Xinyue
- Li Yilong
- Liang Han
- Liang Sheng-Ben
- Lichter Peter
- Lin Pei
- Lin Ziao
- Lin Ziao
- Linehan W. M.
- Lingjærde Ole Christian
- Liu Dongbing
- Liu Eric Minwei
- Liu Eric Minwei
- Liu Fei-Fei Fei
- Liu Fenglin
- Liu Jia
- Liu Xingmin
- Livingstone Julie
- Livitz Dimitri
- Livni Naomi
- Lochovsky Lucas
- Lochovsky Lucas
- Loeffler Markus
- Long Georgina V.
- Lopez-Guillermo Armando
- Lou Shaoke
- Lou Shaoke
- Louis David N.
- Lovat Laurence B.
- López Cristina
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- Malcovati Luca
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- Marchal Kathleen
- Marchal Kathleen
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- Markowetz Florian
- Markowski Julia
- Marks Jeffrey
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- Martincorena Iñigo
- Martincorena Iñigo
- Martinez-Fundichely Alexander
- Martinez-Fundichely Alexander
- Maruvka Yosef E.
- Maruvka Yosef E.
- Mashl R. Jay
- Massie Charlie E.
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- McGillivray Patrick D.
- McGillivray Patrick D.
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- Nakagawa Hidewaki
- Nakamura Hiromi
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- Nangalia Jyoti
- Nastic Mia
- Navarro Arcadi
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- Neal David E.
- Nettekoven Gerd
- Newell Felicity
- Newhouse Steven J.
- Newton Yulia
- Ng Alvin Wei Tian
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- Nicholson Jonathan
- Nicol David
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- Nielsen G. Petur
- Nielsen Morten Muhlig
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- Nik-Zainal Serena
- Niu Beifang
- Noble Michael S.
- Nones Katia
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- null null
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- Ocana David
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- Oesper Layla
- Ogden Christopher
- Ohdan Hideki
- Ohi Kazuhiro
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- Oien Karin A.
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- Okusaka Takuji
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- Ouellette B. F. Francis
- O’Connor Brian D.
- O’Donnell Peter
- O’Donovan Maria
- O’Meara Sarah
- O’Neill Brian Patrick
- O’Neill J. Robert
- Paczkowska Marta
- Paczkowska Marta
- Paiella Salvatore
- Pairojkul Chawalit
- Pajic Marina
- Pan-Hammarström Qiang
- Papaemmanuil Elli
- Papatheodorou Irene
- Paramasivam Nagarajan
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- Pass Harvey
- Pasternack Danielle
- Pastore Alessandro
- Patch Ann-Marie
- Pauporté Iris
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- Pedamallu Chandra Sekhar
- Pedersen Jakob Skou
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- Pederzoli Paolo
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- Perry Marc D.
- Petersen Gloria M.
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- Piñeiro-Yáñez Elena
- Pitkänen Esa
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- Plass Christoph
- Polak Paz
- Pons Tirso
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- Popescu Irinel
- Potapova Olga
- Prasad Aparna
- Preston Shaun R.
- Prinz Manuel
- Pritchard Antonia L.
- Prokopec Stephenie D.
- Provenzano Elena
- Puente Xose S.
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- Pulido-Tamayo Sergio
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- Purdie Colin A.
- P’ng Christine
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- Rabionet Raquel
- Rader Janet S.
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- Radovic Petar
- Raeder Benjamin
- Raine Keiran M.
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- Ramakrishnan Kamna
- Ramalingam Suresh
- Raphael Benjamin J.
- Raphael Benjamin J.
- Rathmell W. Kimryn
- Rausch Tobias
- Rätsch Gunnar
- Reifenberger Guido
- Reimand Jüri
- Reimand Jüri
- Reis-Filho Jorge
- Reuter Victor
- Reyes-Salazar Iker
- Reyes-Salazar Iker
- Reyna Matthew A.
- Reyna Matthew A.
- Reynolds Sheila M.
- Rheinbay Esther
- Rheinbay Esther
- Riazalhosseini Yasser
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- Saini Natalie
- Saito-Adachi Mihoko
- Saksena Gordon
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- Salcedo Adriana
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- Salvia Roberto
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- Shibata Tatsuhiro
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- Shin Seung Jun
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- Shmulevich Ilya
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- Yachida Shinichi
- Yakneen Sergei
- Yamaguchi Rui
- Yamaguchi Takafumi N.
- Yamamoto Masakazu
- Yamamoto Shogo
- Yamaue Hiroki
- Yang Fan
- Yang Huanming
- Yang Jean Y.
- Yang Liming
- Yang Lixing
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- Yang Yang
- Yao Xiaotong
- Yaspo Marie-Laure
- Yates Lucy
- Yau Christina
- Ye Chen
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- Yellapantula Venkata D.
- Yoon Christopher J.
- Yoon Sung-Soo
- Yousif Fouad
- Yu Jun
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- Yuan Ke
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- Yugawa Takashi
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- Zaikova Olga
- Zamora Jorge
- Zapatka Marc
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- Zenz Thorsten
- Zeps Nikolajs
- Zhang Cheng-Zhong
- Zhang Fan
- Zhang Hailei
- Zhang Hongwei
- Zhang Hongxin
- Zhang Jiashan
- Zhang Jing
- Zhang Jing
- Zhang Junjun
- Zhang Xiuqing
- Zhang Xuanping
- Zhang Xuanping
- Zhang Yan
- Zhang Yan
- Zhang Zemin
- Zhao Zhongming
- Zhao Zhongming
- Zheng Liangtao
- Zheng Xiuqing
- Zhou Wanding
- Zhou Yong
- Zhu Bin
- Zhu Helen
- Zhu Hongtu
- Zhu Jingchun
- Zhu Shida
- Zou Lihua
- Zou Lihua
- Zou Xueqing
- Publication venue
- Publication date
- 01/01/2020
- Field of study
Multi-omics datasets represent distinct aspects of the central dogma of molecular biology. Such high-dimensional molecular profiles pose challenges to data interpretation and hypothesis generation. ActivePathways is an integrative method that discovers significantly enriched pathways across multiple datasets using statistical data fusion, rationalizes contributing evidence and highlights associated genes. As part of the ICGC/TCGA Pan-Cancer Analysis of Whole Genomes (PCAWG) Consortium, which aggregated whole genome sequencing data from 2658 cancers across 38 tumor types, we integrated genes with coding and non-coding mutations and revealed frequently mutated pathways and additional cancer genes with infrequent mutations. We also analyzed prognostic molecular pathways by integrating genomic and transcriptomic features of 1780 breast cancers and highlighted associations with immune response and anti-apoptotic signaling. Integration of ChIP-seq and RNA-seq data for master regulators of the Hippo pathway across normal human tissues identified processes of tissue regeneration and stem cell regulation. ActivePathways is a versatile method that improves systems-level understanding of cellular organization in health and disease through integration of multiple molecular datasets and pathway annotations