Dispersion of ADC and SUV in target lesions as observed in staging examinations.

<p>ADC = apparent diffusion coefficient, SUV = standard uptake value.</p

(A-B), Correlation between changes in SUV and treatment response according to WHO and RECIST guidelines.

<p>ADC = apparent diffusion coefficient, SD = stable disease, CR = complete response, RECIST = Response Evaluation Criteria In Solid Tumors, PR = partial response, SUV = standard uptake value, WHO = World Health Organization.</p

Correlation between changes in ADC values and treatment response categories according to SUV (PERCIST), where 1 indicates complete metabolic response, 2 corresponds to partial metabolic response, 3 to stable metabolic disease and 4 to progressive metabolic disease.

<p>ADC = apparent diffusion coefficient, SUV = standard uptake value, PERCIST = PET Response Criteria in Solid Tumors.</p

Correlation between changes in ADC values and treatment response categories according to WHO and RECIST guidelines.

<p>ADC = apparent diffusion coefficient, SD = stable disease, CR = complete response, RECIST = Response Evaluation Criteria In Solid Tumors, PR = partial response, WHO = World Health Organization.</p

Age, gender, primary tumor site, clinical stage and location of affected lymph nodes in patients included in the study.

<p>Age, gender, primary tumor site, clinical stage and location of affected lymph nodes in patients included in the study.</p

Computed tomography-guided preoperative localization of musculoskeletal lesions using the ROLL technique

<div><p>Abstract Objective: To describe the preoperative localization of musculoskeletal lesions with the radioguided occult lesion localization (ROLL) technique. Materials and Methods: In all cases, computed tomography-guided injection of technetium-99m sulfur colloid was performed, directly into or near the suspicious lesion, up to 36 hours before the surgical procedure. Lesions were detected intraoperatively with a gamma probe. Results: We report the cases of six patients submitted to radioguided surgery, including three patients with bone lesions suspicious for metastasis, two patients suspected of recurrent sarcoma, and one patient with no previous diagnosis who had a nodular lesion on the left leg. Patients tolerated the procedure well, and no complications were associated with the puncture. All marked lesions were easily identified intraoperatively and were excised with clear margins. Conclusion: The ROLL technique was effective in the intraoperative localization of occult musculoskeletal lesions, demonstrating that it is a feasible and promising technique for the surgical exploration of selected cases.</p></div