Fusiones y adquisiciones y consejeros independientes. El papel del Comité especial para fusiones y adquisiciones

El presente trabajo incorpora el parámetro de diligencia exigible al consejero independiente a los momentos del procedimiento de fusión donde más destacadamente participa el Consejo de Administración, en el contexto de su función de supervisión aplicable en España. La ausencia de cometidos especiales relativos a la función de supervisión, específicamente en el marco de las fusiones y adquisiciones, contrasta con el amplio desarrollo en Estados Unidos de un Comité Especial para fusiones y adquisiciones formado por consejeros independientes

study of the future of using blockchain technology to facilitate information management in the organization

Complex interactions between industry actors require an intelligent platform in order to efficiently and accurately organize information. Blockchain technology has the potential to bring about fundamental changes in organizations. The issue that this research intends to address is how to use Blockchain technology to facilitate the complexity of interaction coordination in the Social Security Organization in line with the information validation process?The logical essence of this research is the actor-network theory and the practical strategy of the research is futures research. The required data were collected and analyzed based on grounded theory (GT). Objective sampling was employed to select 36 experts as the sample and until theoretical saturation, continued. Then, the scenario-building process continued until reaching the ideal scenario based on the global business network matrix method.After extracting all types of organization scenarios (after implementing Blockchain technology) by scriptwriting, in the ideal scenario this fact was determined that the organization can implement this technology in relation to other parts related to the services of the organization in best ways and use its benefits.with the help of network activists and acceptable Blockchain establishment, all organizations which have the communal approaches can reach the necessary information to facilitate their work approaches in minimum time and maximum fastness. Information circulation in this network would be very manageable and would practically remove many cumbersome routines.

Study regarding the effect of calendula officinalis cream in healing of pressure sores

(Received 13 July, 2008 ; Accepted 29 Oct, 2008) Abstract Background and Purpose: Pressure sore is common among patients with prolonged stay in hospitals or homes. Treatment of such sores is costly and performed by various procedures. Considering the effective role of calendula officinalis in treatment of sores, ulcers and cutaneous inflammations, this study is conducted to determine the effect of this cream in healing pressure sores.Materials and methods: This is a pre/post comparative clinical trial done on 20 patients with pressure sores who received the recommended treatment.The condition of patients such as, duration of pressure sore, and the extent of the sore were recorded. The sore was washed with normal saline, dried, followed by applying calendula cream three times a day for a duration of 4 weeks. Each week, the extent and rate of healing was observed and recorded.Results: The rate of healing in patients under our study was 56.6%. Majority (55%) of patients had partial healing. The time of healing was in weeks 3.5±1.2 (P<0.001). The complete healing occurred in the 3rd and 4th week, subsequent to the beginning of the treatment.Conclusion: Considering the availability of the cream and its affordability, it can be used in the treatment of pressure sores. In addition, it can be used as a drug for treatment of patients who are in hospitals and/or in their homes. J Mazand Univ Med Sci 2008; 18(66):19-25(Persian

Effects of anabolic steroid nandrolone decanoate on ischemic preconditioning in isolated heart of sedentary rats

Background: Previous studies have shown that use of supraphysiologocal doses of anabolic adrogenic steroids (AAS) associated with detrimental cardiovascular effects including ventricular hypertrophy, increased susceptibility to ischaemia/reperfusion injury, impairment of exercise-induced cardioprotection and sudden cardiac death. The aim of the present study was to evaluate the impact of 8 weeks treatment of AAS nandrolone decanoate (10 mg/kg/week), on ischemic preconditioning (IPC) phenomena in isolated hearts of sedentary rats. Materials and Methods: Three groups of animals were studied in the present study. Control ischemia/reperfusion injury group (IR), 2- Ischemic preconditioned group before main test ischemia and reperfusion (IPC+IR), and 3- Nandrolone treated ischemic preconditioned group before main test ischemia and reperfusion (Nan+IPC+IR). After two months of nandrolone and/or its solvent, the isolated Langendorff perfused rat hearts were subjected to 30 min of ischemia followed by 120 min reperfusion. The IPC was induced by three cycles of 3-min occlusion and 3-min reperfusion of the left anterior descending coronary artery (LAD) before main test ischemia. Heart rate, left ventricular developed pressure (LVDP), rate pressure product (RPP), Max dp/dt, Min dp/dt and coronary flow were recorded during experiment. Infarction size was measured after 120 min reperfusion by TTC staining. Results: Eight weeks&rsquo; nandrolone treatment decreased body weight and increased cardiac to body weight ratio in treated rats. Nandrolone increased pre-ischemic base line cardiac function parameters in the rat hearts. Cardiac function recovery parameters in different time points during reperfusion were also greater in nandrolone treated rats compared to their respective controls. IPC decreased infarct size in the rats (P<0.05). Nandrolone could not significantly change the infarct size lowering effect of IPC in the rat heart. Conclusion: The present study revealed that chronic supraphysiological doses of AAS nandrolone, could not impair cardioprotective effects of ischemic preconditioning in isolated rats heart

Evaluation of type IV pilin sub groups in Pseudomonas aeruginosa isolated from environmental samples, cystic fibrosis and burn patients

Background and Aim: Type IV pilin molecule in Pseudomonas aeruginosa with wide functions, has important role in the diversity of the bacterial genome.  According to the latest classification, Type IV pilin is divided to two main subtypes; IVa, IVb. The major subunit encoding Type IV pilin subtypes; IVa, IVb is pilA and pilS2 genes respectively which serve as a marker for the detection of the Type IV pilin subtypes. The purpose of the current study was to evaluate the frequency of pilA and pilS2 gene in cystic fibrosis, burns, and environmental isolates. Materials and Methods: The samples for P.aeruginosa were collected from cystic fibrosis, burns, and environment wastewater during the April 2013 to December 2013. Samples were cultured and identified using microbial and biochemical methods. DNA of isolates was extracted by commercial kit. PCR was performed using specific primers. Statistical analysis was done using SPSS 17.0 software. Results: A total of 100 P.aeruginosa isolates were collected; 30 cystic fibrosis, 30 burn, 40 environmental. The prevalence of the  pilA gene were 63.3% , 56.7% and 45/2%  for cystic fibrosis, for burns  and environmental strains . The PilS2 gene frequency was 57.5% of the environmental isolates, 67.5% of cystic fibrosis strains and 73.3 % of the isolates were burned. Conclusions: Our study showed that the frequency of P.aeruginosa T4P major pilin subunits in our P. aeruginosa population was high. The incidence of pilS2 gene was greater than pilA and was more frequent in Pseudomonas aeruginosa isolated from hospitalized burn patients

Cohort Profile Update: The Amirkola Health and Ageing Project (AHAP)

The original cohort study of AHAP started in 2011 on 1616 elderly residents of Amirkola, northern part of Iran near the Caspian Sea. The main goal of this study was to comprehensively evaluate the health of the elderly in the region with the emphasis on chronic diseases such as osteoporosis. The first cohort profile was published in the International Journal of Epidemiology in 2014. The phase 1 AHAP showed the elevated level of some diseases and conditions including osteoporosis, metabolic syndrome, obesity, vision problems and relatively low levels of oral health. Therefore, the second phase of this cohort started with more complete population coverage in 2016, not only to collect and record the information based on previous protocol, but also consider new areas such as nutritional status, complete eye and dental examinations and health assessment on the basis of Iranian Traditional Medicine. The new aspect of this project is to conduct clinical and laboratory examinations at the health center to extend more facilities to the elderly. In addition to serum and DNA, samples of saliva, hair and nails are collected and kept under standard conditions in the biobank of this cohort. Researchers can apply for access to data or suggest a collaborative study by submitting the proposal to AHAP committee

A comparative study of the effect of the oral gavage and the intraperitioneal administration of Cinnamomum camphora on the number of embryos in mice

Background: According to a popular Iranian belief, Camphor can not only suppress libido but also decrease the function of the reproductive system. In this regard, this study was conducted to Methods: In this study, 40 male and 80 female albino mice, weighing 30-35 g, were randomly divided into 8 groups, including a control group, a sham group that received the vehicle only (olive oil), and six experimental groups that received Camphor. Three experimental groups received camphor by p.o. (gavage) and the other three experimental groups received camphor by i.p. (intraperitioneal) in doses of 10, 20, and 40 mg/kg for 15 days. Mating was confirmed after coupling a male with a female mouse. Vaginal plaque was also considered for mating. Embryos were examined during the period of gestation. Results: The mean number of embryos in control, sham, and received Camphor (10, 20, and 40 mg/Kg) by o. p. were 9.7 ± 4.6, 7.3 ± 4.3, 9.9 ±4.7, 8.6 ± 5.2, and 8.3 ±4.8, respectively. The mean number of embryo in received Camphor (10, 20, and 40 mg/Kg) by i. p. were 7.6 ± 5.4, 8.3 ± 3.4, and 7.3 ± 6.2, respectively. There were no significant differences in the number of embryos between control, sham, and experimental groups in both groups. Conclusion: Further investigations with more focus on the effect of Camphor on sexual behavior in mice need to be carried out